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Research ArticleBrain

Echo-Planar Functional MR Imaging of Epilepsy with Concurrent EEG Monitoring

Mahesh R. Patel, Andrew Blum, Justin D. Pearlman, Naveed Yousuf, John R. Ives, Saowalak Saeteng, Donald L. Schomer and Robert R. Edelman
American Journal of Neuroradiology November 1999, 20 (10) 1916-1919;
Mahesh R. Patel
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Andrew Blum
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Justin D. Pearlman
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Naveed Yousuf
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John R. Ives
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Saowalak Saeteng
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Donald L. Schomer
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Robert R. Edelman
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    fig 1.

    Diagram illustrating the acquisition of MR data triggered to the presence (ON state) or absence (OFF state) of an EEG discharge.

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    fig 2.

    Composite image showing BOLD activation superimposed over T1-weighted anatomic image (reconstructed from 3D MPRAGE acquisition), which corresponds to EEG activity. The region of activation covers a 4.8-cm2 area of the left lateral temporal lobe. This region is distinguished by high positive z scores, with a positive z score maximum of 6.2 and a mean of 2.6 ± 1.1 (standard error, 0.1).

  • fig 3.
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    fig 3.

    Composite images showing BOLD activation superimposed over T1-weighted anatomic image (reconstructed from 3D MPRAGE acquisition), which corresponds to EEG activity.

    A, Right posterior temporal lobe BOLD activation is shown. The region of activation covers a 4.4-cm2 area, with a positive z score maximum of 2.9 and a mean of 1.2 ± 0.6 (standard error, 0.06).

    B, Additional focus of right parietal BOLD activation is seen, which is in contiguity with the posterior temporal lobe activation above. Within this 3.2-cm2 region of activation, the positive z score maximum was 3.6, with a mean of 1.6 ± 0.8 (standard error, 0.1).

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    fMR BOLD activity correlation with EEG localization

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American Journal of Neuroradiology
Vol. 20, Issue 10
1 Nov 1999
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Echo-Planar Functional MR Imaging of Epilepsy with Concurrent EEG Monitoring
Mahesh R. Patel, Andrew Blum, Justin D. Pearlman, Naveed Yousuf, John R. Ives, Saowalak Saeteng, Donald L. Schomer, Robert R. Edelman
American Journal of Neuroradiology Nov 1999, 20 (10) 1916-1919;

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Echo-Planar Functional MR Imaging of Epilepsy with Concurrent EEG Monitoring
Mahesh R. Patel, Andrew Blum, Justin D. Pearlman, Naveed Yousuf, John R. Ives, Saowalak Saeteng, Donald L. Schomer, Robert R. Edelman
American Journal of Neuroradiology Nov 1999, 20 (10) 1916-1919;
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  • Cortical/subcortical BOLD changes associated with epileptic discharges: An EEG-fMRI study at 3 T
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