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Research ArticleSPINE

MR Findings in AIDS-Associated Myelopathy

June Chong, Alessandro Di Rocco, Michele Tagliati, Fabio Danisi, David M. Simpson and Scott W. Atlas
American Journal of Neuroradiology September 1999, 20 (8) 1412-1416;
June Chong
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Alessandro Di Rocco
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Michele Tagliati
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Fabio Danisi
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David M. Simpson
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Scott W. Atlas
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    fig 1.

    A–C, T1-weighted sagittal (A), T2-weighted sagittal (B), and T2-weighted axial (C) MR images through the thoracic spine of an AIDS patient with mild myelopathy show cord atrophy and intramedullary cord signal abnormality

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    fig 2.

    A–C, Sagittal T1-weighted (A), sagittal T2-weighted (B), and axial T2-weighted (C) MR images of the cervical spine in a patient with severe myelopathy show cervical cord atrophy and extensive abnormal intrinsic cord signal intensity

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    fig 3.

    A and B, Noncontrast sagittal T1-weighted (A) and T2-weighted (B) images show a normal-sized cervicothoracic cord with intramedullary thoracic cord signal abnormality and no associated cord enlargement. There was no evidence of abnormal enhancement in the postcontrast study (not shown)

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    fig 4.

    A, Luxol fast blue stain of the spinal cord in a patient with AIDS-associated myelopathy (not from our series) shows pathologic changes predominantly involving the posterior and lateral columns (arrows).

    B, A magnified view of the same specimen as in A shows vacuolization (small arrows) and lipid-laden macrophages (large arrows) scattered throughout the involved cord.

    (Reprinted with permission from Mandell GL. Atlas of Infectious Diseases, I: AIDS. 2nd ed. Philadelphia: Current Medicine, Inc; 1997.)

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    TABLE 1:

    Criteria for clinical diagnosis of AIDS-associated myelopathy

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    TABLE 2:

    Summary of results of MR findings and clinical rating of myelopathy in 21 patients

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American Journal of Neuroradiology
Vol. 20, Issue 8
1 Sep 1999
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Cite this article
June Chong, Alessandro Di Rocco, Michele Tagliati, Fabio Danisi, David M. Simpson, Scott W. Atlas
MR Findings in AIDS-Associated Myelopathy
American Journal of Neuroradiology Sep 1999, 20 (8) 1412-1416;

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MR Findings in AIDS-Associated Myelopathy
June Chong, Alessandro Di Rocco, Michele Tagliati, Fabio Danisi, David M. Simpson, Scott W. Atlas
American Journal of Neuroradiology Sep 1999, 20 (8) 1412-1416;
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