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Research ArticleBRAIN

Development and Aging of the Cerebrum: Assessment with Proton MR Spectroscopy

Tsuyoshi Kadota, Takashi Horinouchi and Chikazumi Kuroda
American Journal of Neuroradiology January 2001, 22 (1) 128-135;
Tsuyoshi Kadota
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Takashi Horinouchi
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Chikazumi Kuroda
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    fig 1.

    A and B, Sagittal (A) and axial (B) MR images of a healthy 20-year-old woman show the outlines of the spectroscopic VOI and typical position of 12 voxels in the centrum semiovale. Six voxels were in bilateral anterior, middle, and posterior regions containing predominantly white matter (white open boxes) and six voxels were in bilateral mesial cortex with mostly mesial gray matter of the anterior, middle, and posterior regions (black open boxes), respectively.

    C, Proton spectra obtained in right middle white matter (white open box) are shown. NAA, Cho, and Cr peaks were quantified by applying gaussian curve fittings.

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    fig 2.

    A and B, Scatter plots and fitting curves of averaged NAA/Cho ratios as a function of age in white matter (A) and gray matter (B) of the centrum semiovale.

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    fig 3.

    A–F, Scatter plots and fitting curves for male and female NAA/Cho ratios as a function of age in anterior (A), middle (B), and posterior (C) white matter, and anterior (D), middle (E), and posterior (F) gray matter of the right (R) and left (L) centrum semiovale.

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    fig 3.

    Continued.

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American Journal of Neuroradiology
Vol. 22, Issue 1
1 Jan 2001
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Cite this article
Tsuyoshi Kadota, Takashi Horinouchi, Chikazumi Kuroda
Development and Aging of the Cerebrum: Assessment with Proton MR Spectroscopy
American Journal of Neuroradiology Jan 2001, 22 (1) 128-135;

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Development and Aging of the Cerebrum: Assessment with Proton MR Spectroscopy
Tsuyoshi Kadota, Takashi Horinouchi, Chikazumi Kuroda
American Journal of Neuroradiology Jan 2001, 22 (1) 128-135;
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