Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • ASNR Foundation Special Collection
    • Most Impactful AJNR Articles
    • Photon-Counting CT
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • ASNR Foundation Special Collection
    • Most Impactful AJNR Articles
    • Photon-Counting CT
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR is seeking candidates for the AJNR Podcast Editor. Read the position description.

Research ArticleBRAIN

Concordant Pre- and Postsynaptic Deficits of Dopaminergic Neurotransmission in Neurologic Wilson Disease

Henryk Barthel, Wieland Hermann, Regine Kluge, Swen Hesse, David R. Collingridge, Armin Wagner and Osama Sabri
American Journal of Neuroradiology February 2003, 24 (2) 234-238;
Henryk Barthel
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Wieland Hermann
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Regine Kluge
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Swen Hesse
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
David R. Collingridge
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Armin Wagner
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Osama Sabri
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. ↵
    Oder W, Prayer L, Grimm G, et al. Wilson’s disease: evidence of subgroups derived from clinical findings and brain lesions. Neurology 1993;43:120–124
    Abstract/FREE Full Text
  2. ↵
    Barbosa ER, Caramelli P, Bacheschi LA, et al. Wilson’s disease: magnetic resonance imaging (MRI) with clinical correlations in 16 cases. Rev Paul Med 1993;111(3):407–411
    PubMed
  3. ↵
    Booij J, Tissingh G, Winogrodzka A, van Royen EA. Imaging of the dopaminergic neurotransmission system using single-photon emission tomography and positron emission tomography in patients with Parkinsonism. Eur J Nucl Med 1999;26:171–182
    CrossRefPubMedWeb of Science
  4. ↵
    Tatsch K, Schwarz J, Oertel WH, Kirsch CM. SPECT imaging of dopamine D2 receptors with 123I-IBZM: initial experience in controls and patients with Parkinson’s syndrome and Wilson’s disease. Nucl Med Commun 1991;12:699–707
    PubMedWeb of Science
  5. ↵
    Snow BJ, Bhatt M, Martin WR, Li D, Calne BD. The nigrostriatal dopaminergic pathway in Wilson’s disease studied with positron emission tomography. J Neurol Neurosurg Psych 1991;54:12–17
    Abstract/FREE Full Text
  6. ↵
    Westermark K, Tedroff J, Thuomas KA, et al. Neurological Wilson’s disease studies with magnetic resonance imaging and with positron emission tomography using dopaminergic markers. Mov Disord 1995;10:596–603
    CrossRefPubMed
  7. ↵
    Schlaug G, Hefter H, Engelbrecht V, et al. Neurological impairment and recovery in Wilson’s disease: evidence from PET and MRI. J Neurol Sci 1996;136:129–139
    CrossRefPubMed
  8. ↵
    Oder W, Brücke H, Kollegger H, Spatt J, Asenbaum S, Deecke L. Dopamine D2 receptor binding is reduced in Wilson’s disease: correlation of neurological deficits with striatal 123I-Iodobenzamide binding. J Neural Transm 1996;103:1093–1103
    CrossRef
  9. ↵
    Jeon B, Kim J, Jeong JM, et al. Dopamine transporter imaging with [123I]-β-CIT demonstrates presynaptic nigrostriatal dopaminergic damage in Wilson’s disease. J Neurol Neurosurg Psych 1998;65:60–64
    Abstract/FREE Full Text
  10. ↵
    Biesold D, Günther K. Improved method for investigation of copper metabolism in patients with Wilson’s disease using 64Cu. Clin Chem Acta 1972;42:353–359
  11. ↵
    Hermann W, Tietze F, Villmann T, Grahmann F, Wagner A. Clinical and fine motor therapy assessment in Wilson’s disease. Nervenarzt 2000;71:970–974
    PubMed
  12. ↵
    Barthel H, Sorger D, Kühn HJ, Wagner A, Kluge R, Hermann W. Differential alteration of the nigrostriatal dopaminergic system in Wilson’s disease investigated with [123I] β-CIT and high resolution SPECT. Eur J Nucl Med 2001;28:1656–1663
    PubMed
  13. ↵
    van Dyck CH, Seibyl JP, Malison RT, et al. Age-related decline in striatal dopamine transporter binding with Iodine-123-β-CIT SPECT. J Nucl Med 1995;36:1175–1181
    Abstract/FREE Full Text
  14. ↵
    Toyama H, Ichise M, Ballinger JR, Fornazzari L, Kirsh JC. Dopamine D2 receptor SPECT imaging: basic in vivo characteristics and clinical applications of 123I-IBZM in humans. Ann Nucl Med 1993;7:29–38
    CrossRefPubMed
  15. ↵
    Fletscher N. Movement disorders. In: Donaghy M, ed. Brain’s Diseases of the Nervous System. Oxford: Oxford University Press; 2001:1015–1023
  16. ↵
    King AD, Walshe JM, Kendall BE, et al. Cranial MR imaging in Wilson’s disease. AJR Am J Roentgenol 1996;167:1579–1584
    PubMedWeb of Science
  17. ↵
    Alanen A, Komu M, Penttinen M, Leino R. Magnetic resonance imaging and proton MR spectroscopy in Wilson’s disease. Br J Radiol 1999;72:749–756
    Abstract
  18. ↵
    Magalhaes AC, Caramelli P, Menezes JR, et al. Wilson’s disease: MRI with clinical correlation. Neuroradiology 1994;36:97–110
    CrossRefPubMed
  19. ↵
    Weisner B, Hartard C, Dieu C. CSF copper concentration: a new parameter for diagnosis and monitoring therapy of Wilson’s disease with cerebral manifestation. J Neurol Sci 1987;79:2290–2237
  20. ↵
    Kodama H, Okabe I, Yanagisawa M, et al. Does CSF copper level in Wilson disease reflect copper accumulation in the brain? Pediatr Neurol 1988;4:35–37
    CrossRefPubMedWeb of Science
  21. ↵
    Barbeau A, Friesen H. Treatment of Wilson’s disease with L-dopa after failure with penicillamine. Lancet 1970;1:1180–1181
  22. ↵
    Berio A, Vento R, Di Stefano A. Favorable results with an association of L-dopa and amantadine added to penicillamine in the treatment of Wilson’s disease. Minerva Pediatr 1973;25:807–813
    PubMed
  23. ↵
    Gelmers HJ, Troost J, Willemse J. Wilson’s disease: Modification by L-dopa. Neuropediatriatrics 1973;4:453–457
  24. ↵
    Frankel JP, Hughes A, Lees AJ, Stern GM, Walshe JM. Use of apomorphine to test for dopamine responsiveness in Wilson’s disease. Lancet 1989;2:801–802
  25. ↵
    Morgan JP, Preziosi TJ, Bianchine JR. Ineffectiveness of L-dopa as supplement to penicillamine in a case of Wilson’s disease. Lancet 1970;26:659
  26. ↵
    Wenning GK, Quinn NP. Parkinsonism: multiple system atrophy. Baillieres Clin Neurol 1997;6:187–204
    PubMed
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 24 (2)
American Journal of Neuroradiology
Vol. 24, Issue 2
1 Feb 2003
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Concordant Pre- and Postsynaptic Deficits of Dopaminergic Neurotransmission in Neurologic Wilson Disease
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
Henryk Barthel, Wieland Hermann, Regine Kluge, Swen Hesse, David R. Collingridge, Armin Wagner, Osama Sabri
Concordant Pre- and Postsynaptic Deficits of Dopaminergic Neurotransmission in Neurologic Wilson Disease
American Journal of Neuroradiology Feb 2003, 24 (2) 234-238;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Concordant Pre- and Postsynaptic Deficits of Dopaminergic Neurotransmission in Neurologic Wilson Disease
Henryk Barthel, Wieland Hermann, Regine Kluge, Swen Hesse, David R. Collingridge, Armin Wagner, Osama Sabri
American Journal of Neuroradiology Feb 2003, 24 (2) 234-238;
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Methods
    • Results
    • Discussion
    • Conclusion
    • Acknowledgments
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • The role of DAT-SPECT in movement disorders
  • Copper{middle dot}Dopamine Complex Induces Mitochondrial Autophagy Preceding Caspase-independent Apoptotic Cell Death
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Optimal MRI Sequence for Identifying Occlusion Location in Acute Stroke: Which Value of Time-Resolved Contrast-Enhanced MRA?
  • Evaluating the Effects of White Matter Multiple Sclerosis Lesions on the Volume Estimation of 6 Brain Tissue Segmentation Methods
  • Quiet PROPELLER MRI Techniques Match the Quality of Conventional PROPELLER Brain Imaging Techniques
Show more BRAIN

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

Special Collections

  • AJNR Awards
  • ASNR Foundation Special Collection
  • Most Impactful AJNR Articles
  • Photon-Counting CT
  • Spinal CSF Leak Articles (Jan 2020-June 2024)

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire