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Research ArticleBRAIN

Voxel-Based Morphometric Comparison Between Early- and Late-Onset Mild Alzheimer’s Disease and Assessment of Diagnostic Performance of Z Score Images

Kazunari Ishii, Takashi Kawachi, Hiroki Sasaki, Atsushi K Kono, Tetsuya Fukuda, Yoshio Kojima and Etsuro Mori
American Journal of Neuroradiology February 2005, 26 (2) 333-340;
Kazunari Ishii
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Takashi Kawachi
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Hiroki Sasaki
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Atsushi K Kono
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Tetsuya Fukuda
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Yoshio Kojima
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Etsuro Mori
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References

  1. ↵
    Seltzer B, Sherwin I. A comparison of clinical features in early- and late-onset primary degenerative dementia: one entity or two? Arch Neurol 1983;40:143–146
    CrossRefPubMedWeb of Science
  2. ↵
    Iversen LL. Differences between early and late-onset Alzheimer’s disease. Neurobiol Aging 1987;8:554–555
    CrossRefPubMedWeb of Science
  3. ↵
    Armstrong RA, Nochlin D, Bird TD. Neuropathological heterogeneity in Alzheimer’s disease: a study of 80 cases using principal components analysis. Neuropathology 2000;20:31–37
    CrossRefPubMed
  4. ↵
    Mielke R, Herholz K, Grond M, Kessler J, Heiss WD. Differences of regional cerebral glucose metabolism between presenile and senile dementia of Alzheimer type. Neurobiol Aging 1992;13:93–98
    CrossRefPubMedWeb of Science
  5. Caffarra P, Scaglioni A, Malvezzi L, Previdi P, Spreafico L, Salmaso D. Age at onset and SPECT imaging in Alzheimer’s disease. Dementia 1993;4:342–346
  6. Ichimiya A, Herholz K, Mielke R, Kessler J, Slansky I, Heiss WD. Difference of regional cerebral metabolic pattern between presenile and senile dementia of the Alzheimer type: a factor analytic study. J Neurol Sci 1994;123:11–17
    CrossRefPubMedWeb of Science
  7. Yasuno F, Imamura T, Hirono N, et al. Age at onset and regional cerebral glucose metabolism in Alzheimer’s disease. Dement Geriatr Cogn Disord 1998;9:63–67
    CrossRefPubMedWeb of Science
  8. ↵
    Sakamoto S, Ishii K, Sasaki M, et al. Differences in cerebral metabolic impairment between early and late onset types of Alzheimer’s disease. J Neurol Sci 2002;200:27–32
    CrossRefPubMedWeb of Science
  9. ↵
    Ashburner J, Friston KJ. Voxel-based morphometry: the methods. Neuroimage 2000;11:805–821
    CrossRefPubMedWeb of Science
  10. ↵
    Baron JC, Chetelat G, Desgranges B, et al. In vivo mapping of gray matter loss with voxel-based morphometry in mild Alzheimer’s disease. Neuroimage 2001;14:298–309
    CrossRefPubMedWeb of Science
  11. ↵
    Chetelat G, Desgranges B, De La Sayette V, Viader F, Eustache F, Baron JC. Mapping gray matter loss with voxel-based morphometry in mild cognitive impairment. Neuroreport 2002;13:1939–1943
    CrossRefPubMedWeb of Science
  12. ↵
    McKhann G, DrachmanD, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer’s disease: report of the NINCDS/ADRDA work group under the auspices of the Department of Health and Human Services task force on Alzheimer’s disease. Neurology 1984;34:939–944
    Abstract/FREE Full Text
  13. ↵
    Folstein MF, Folstein SE, McHugh PR. “Mini-mental state”: a practical method for grading the cognitive state of patients for the clinician. J Psychiat Res 1975;12:189–198
    CrossRefPubMedWeb of Science
  14. ↵
    Ishii K, Sasaki M, Matsui M, et al. A diagnostic method for suspected Alzheimer’s disease using H215O positron emission tomography perfusion Z score. Neuroradiology 2000;42:787–794
    CrossRefPubMed
  15. ↵
    Chetelat G, Baron JC. Early diagnosis of Alzheimer’s disease: contribution of structural neuroimaging. Neuroimage 2003;18:525–541
    CrossRefPubMedWeb of Science
  16. ↵
    Good CD, Johnsrude IS, Ashburner J, Henson RN, Friston KJ, Frackowiak RS. A voxel-based morphometric study of aging in 465 normal adult human brains. Neuroimage 2001;14:21–36
    CrossRefPubMedWeb of Science
  17. ↵
    Hanyu H, Asano T, Sakurai H, Tanaka Y, Takasaki M, Abe K. MR analysis of the substantia innominata in normal aging, Alzheimer disease, and other types of dementia. AJNR Am J Neuroradiol 2002;23:27–32
    Abstract/FREE Full Text
  18. ↵
    Kuhl DE. Imaging local brain function with positron emission tomography. Radiology 1984;150:625–631
    PubMedWeb of Science
  19. Minoshima S, Foster NL, Kuhl DE. Posterior cingulate cortex in Alzheimer’s disease (letter). Lancet 1994;344:895
    PubMedWeb of Science
  20. ↵
    Ishii K, Sasaki M, Yamaji S, Sakamoto S, Kitagaki H, Mori E. Demonstration of decreased posterior cingulate perfusion in mild Alzheimer’s disease by means of H215O positron emission tomography. Eur J Nucl Med 1997;24:670–673
    PubMed
  21. ↵
    Small GW, Kuhl DE, Riege WH, et al. Cerebral glucose metabolic patterns in Alzheimer’s disease: effect of gender and age at dementia onset. Arch Gen Psychiatry 1989;46:527–532
    CrossRefPubMedWeb of Science
  22. ↵
    Jacobs D, Sano M, Marder K, et al. Age at onset of Alzheimer’s disease: relation to pattern of cognitive dysfunction and rate of decline. Neurology 1994;44:1215–1220
    Abstract/FREE Full Text
  23. ↵
    Coleman PD, Flood DG. Neuron number and dendritic extent in normal aging and Alzheimer’s disease. Neurobiol Aging 1987;8:521–545
    CrossRefPubMedWeb of Science
  24. ↵
    Ball MJ. Neuronal loss, neurofibrillary tangles and granulovascular degeneration in the hippocampus with ageing and dementia: a quantitative study. Acta Neuropathol 1977;37:111–118
    CrossRefPubMedWeb of Science
  25. ↵
    Thompson PM, Mega MS, Woods RP, et al. Cortical change in Alzheimer’s disease detected with a disease-specific population-based brain atlas. Cereb Cortex 2001;11:1–16
    Abstract/FREE Full Text
  26. ↵
    Ohnishi T, Hoshi H, Nagamachi S, et al. Regional cerebral blood flow study with 123I-IMP in patients with degenerative dementia. AJNR Am J Neuroradiol 1991;12:513–520
    Abstract/FREE Full Text
  27. ↵
    Bookstein FL. “Voxel-based morphometry” should not be used with imperfectly registered images. Neuroimage 2001;14:1454–1462
    CrossRefPubMedWeb of Science
  28. ↵
    Ashburner J, Friston KJ. Why voxel-based morphometry should be used. Neuroimage 2001;14:1238–1243
    CrossRefPubMedWeb of Science
  29. ↵
    Good CD, Scahill RI, Fox NC, et al. Automatic differentiation of anatomical patterns in the human brain: validation with studies of degenerative dementias. Neuroimage 2002;17:29–46
    CrossRefPubMedWeb of Science
  30. Frisoni GB, Testa C, Zorzan A, et al. Detection of gray matter loss in mild Alzheimer’s disease with voxel based morphometry. J Neurol Neurosurg Psychiatry 2002;73:657–664
    Abstract/FREE Full Text
  31. Boxer AL, Rankin KP, Miller BL, et al. Cinguloparietal atrophy distinguishes Alzheimer disease from semantic dementia. Arch Neurol 2003;60:949–956
    CrossRefPubMedWeb of Science
  32. Karas GB, Burton EJ, Rombouts SA, et al. A comprehensive study of gray matter loss in patients with Alzheimer’s disease using optimized voxel-based morphometry. Neuroimage 2003;18:895–907
    CrossRefPubMedWeb of Science
  33. ↵
    Busatto GF, Garrido GE, Almeida OP, et al. A voxel-based morphometry study of temporal lobe gray matter reductions in Alzheimer’s disease. Neurobiol Aging 2003;24:221–231
    CrossRefPubMedWeb of Science
  34. ↵
    De Leon MJ, Golomb J, George AE, et al. The radiologic prediction of Alzheimer disease: the atrophic hippocampal formation. AJNR Am J Neuroradiol 1993;14:897–906
    Abstract/FREE Full Text
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American Journal of Neuroradiology: 26 (2)
American Journal of Neuroradiology
Vol. 26, Issue 2
1 Feb 2005
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Kazunari Ishii, Takashi Kawachi, Hiroki Sasaki, Atsushi K Kono, Tetsuya Fukuda, Yoshio Kojima, Etsuro Mori
Voxel-Based Morphometric Comparison Between Early- and Late-Onset Mild Alzheimer’s Disease and Assessment of Diagnostic Performance of Z Score Images
American Journal of Neuroradiology Feb 2005, 26 (2) 333-340;

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Voxel-Based Morphometric Comparison Between Early- and Late-Onset Mild Alzheimer’s Disease and Assessment of Diagnostic Performance of Z Score Images
Kazunari Ishii, Takashi Kawachi, Hiroki Sasaki, Atsushi K Kono, Tetsuya Fukuda, Yoshio Kojima, Etsuro Mori
American Journal of Neuroradiology Feb 2005, 26 (2) 333-340;
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  • Clinical syndromes associated with posterior atrophy: Early age at onset AD spectrum
  • Role of Neuroimaging in Alzheimer's Disease, with Emphasis on Brain Perfusion SPECT
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