Reversal of Delayed Vasospasm by TS-011 in the Dual Hemorrhage Dog Model of Subarachnoid Hemorrhage

References

1. ↵
   Gebremedhin D, Lange AR, Lowry TF, et al. Production of 20-HETE and its role in autoregulation of cerebral blood flow. Circ Res 2000;87:60–65

   Abstract/FREE Full Text
2. Harder DR, Roman RJ, Gebremedhin D. Molecular mechanisms controlling nutritive blood flow: role of cytochrome P450 enzymes. Acta Physiol Scand 2000;168:543–49

   CrossRefPubMedWeb of Science
3. ↵
   Gebremedhin D, Lange AR, Narayanan J, et al. Cat cerebral arterial smooth muscle cells express cytochrome P450 4A2 enzyme and produce the vasoconstrictor 20-HETE which enhances L-type Ca²⁺ current. J Physiol 1998;507(Pt 3):771–81
4. ↵
   Kehl F, Cambj-Sapunar L, Maier KG, et al. 20-HETE contributes to the acute fall in cerebral blood flow after subarachnoid hemorrhage in the rat. Am J Physiol Heart Circ Physiol 2002;282:H1556–65

   Abstract/FREE Full Text
5. ↵
   Yu M, Cambj-Sapunar L, Kehl F, et al. Effects of a 20-HETE antagonist and agonists on cerebral vascular tone. Eur J Pharmacol 2004;486:297–306

   CrossRefPubMedWeb of Science
6. ↵
   Miyata N, Seki T, Tanaka Y, et al. Beneficial effects of a new 20-hydroxyeicosatetraenoic acid synthesis inhibitor, TS-011 [N-(3-chloro-4-morpholin-4-yl) phenyl-N’-hydroxyimido formamide], on hemorrhagic and ischemic stroke. J Pharmacol Exp Ther 2005;314:77–85. Epub 2005 Apr 14

   Abstract/FREE Full Text
7. ↵
   Kaoutzanis M, Yokota M, Sibilia R, et al. Neurologic evaluation in a canine model of single and double subarachnoid hemorrhage. J Neurosci Methods 1993;50:301–07

   CrossRefPubMed
8. ↵
   Kuwayama A, Zervas NT, Belson R, et al. A model for experimental cerebral arterial spasm. Stroke 1972;3:49–56

   Abstract/FREE Full Text
9. ↵
   Weir B, MacDonald L. Cerebral vasospasm. Clin Neurosurg 1993;40:40–55

   PubMed
10. ↵
    Weir B, Macdonald RL, Stoodley M. Etiology of cerebral vasospasm. Acta Neurochir Suppl 1999;72:27–46

    PubMed
11. ↵
    Sobey CG, Heistad DD, Faraci FM. Effect of subarachnoid hemorrhage on dilatation of rat basilar artery in vivo. Am J Physiol 1996;271(1 Pt 2):H126–32
12. Sobey CG, Quan L. Impaired cerebral vasodilator responses to NO and PDE V inhibition after subarachnoid hemorrhage. Am J Physiol 1999;277(5 Pt 2):H1718–24
13. ↵
    Prunell GF, Mathiesen T, Diemer NH, et al. Experimental subarachnoid hemorrhage: subarachnoid blood volume, mortality rate, neuronal death, cerebral blood flow, and perfusion pressure in three different rat models. Neurosurgery 2003;52:165–76

    CrossRefPubMedWeb of Science
14. Faraci FM, Heistad DD. Regulation of the cerebral circulation: role of endothelium and potassium channels. Physiol Rev 1998;78:53–97

    Abstract/FREE Full Text
15. ↵
    Jackowski A, Crockard A, Burnstock G, et al. The time course of intracranial pathophysiological changes following experimental subarachnoid haemorrhage in the rat. J Cereb Blood Flow Metab 1990;10:835–49

    PubMedWeb of Science
16. ↵
    Cambj-Sapunar L, Yu M, Harder DR, et al. Contribution of 5-hydroxytryptamine1B receptors and 20-hydroxyeiscosatetraenoic acid to fall in cerebral blood flow after subarachnoid hemorrhage. Stroke 2003;34:1269–75. Epub 2003 Apr 3

    Abstract/FREE Full Text
17. ↵
    Delgado TJ, Brismar J, Svendgaard NA. Subarachnoid haemorrhage in the rat: angiography and fluorescence microscopy of the major cerebral arteries. Stroke 1985;16:595–602

    Abstract/FREE Full Text
18. Oyekan A, Balazy M, McGiff JC. Renal oxygenases: differential contribution to vasoconstriction induced by ET-1 and ANG II. Am J Physiol 1997;273:R293–300

    PubMedWeb of Science
19. Carroll MA, Kemp R, Cheng MK, et al. Regulation of preglomerular microvascular 20-hydroxyeicosatetraenoic acid levels by salt depletion. Med Sci Monit 2001;7:567–72

    PubMed
20. Alonso-Galicia M, Hudetz AG, Shen H, et al. Contribution of 20-HETE to vasodilator actions of nitric oxide in the cerebral microcirculation. Stroke 1999;30:2727–34

    Abstract/FREE Full Text
21. Harder DR, Gebremedhin D, Narayanan J, et al. Formation and action of a P-450 4A metabolite of arachidonic acid in cat cerebral microvessels. Am J Physiol 1994;266:H2098–107

    PubMedWeb of Science
22. Sun CW, Falck JR, Okamoto H, et al. Role of cGMP versus 20-HETE in the vasodilator response to nitric oxide in rat cerebral arteries. Am J Physiol Heart Circ Physiol 2000;279:H339–50

    Abstract/FREE Full Text
23. Harder DR, Lange AR, Gebremedhin D, et al. Cytochrome P450 metabolites of arachidonic acid as intracellular signaling molecules in vascular tissue. J Vasc Res 1997;34:237–43

    CrossRefPubMedWeb of Science
24. ↵
    Sobey CG. Cerebrovascular dysfunction after subarachnoid haemorrhage: novel mechanisms and directions for therapy. Clin Exp Pharmacol Physiol 2001;28:926–29

    CrossRefPubMedWeb of Science
25. ↵
    Hop JW, Rinkel GJ, Algra A, et al. Case-fatality rates and functional outcome after subarachnoid hemorrhage: a systematic review. Stroke 1997;28:660–64

    Abstract/FREE Full Text
26. ↵
    Schievink WI, Wijdicks EF, Parisi JE, et al. Sudden death from aneurysmal subarachnoid hemorrhage. Neurology 1995;45:871–74

    Abstract/FREE Full Text
27. Olafsson E, Hauser WA, Gudmundsson G. A population-based study of prognosis of ruptured cerebral aneurysm: mortality and recurrence of subarachnoid hemorrhage. Neurology 1997;48:1191–95

    Abstract/FREE Full Text
28. ↵
    Broderick JP, Brott TG, Duldner JE, et al. Initial and recurrent bleeding are the major causes of death following subarachnoid hemorrhage. Stroke 1994;25:1342–47

    Abstract/FREE Full Text
29. ↵
    Crompton MR. Cerebral infarction following the rupture of cerebral berry aneurysms. Brain 1964;87:263–79

    FREE Full Text