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OtherBRAIN

Radiologic Findings in a Patient with Frontal Parafalcine Dendritic Cell Histiocytoma

A.S. Abi-Ghanem, O. Uzuner, F.B. Askin and D.M. Yousem
American Journal of Neuroradiology November 2007, 28 (10) 1991-1992; DOI: https://doi.org/10.3174/ajnr.A0728
A.S. Abi-Ghanem
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O. Uzuner
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F.B. Askin
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D.M. Yousem
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    Fig 1.

    MR imaging findings of the tumor at presentation. A, Axial T2-weighted and (B) axial postcontrast T1-weighted images demonstrate an avidly enhancing extra-axial mass centered in parafalcine location bilaterally, mainly on the right. C, After surgical intervention. Axial postcontrast T1-weighted image shows resection of the tumor locating in the right parafalcine location with a residual tumor at the superior sagittal sinus and left parafalcine region.

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    Fig 2.

    Pathology smears from surgical specimen. The lesion is composed of sheets of large cells with prominent glassy, eosinophilic cytoplasm and prominent red nucleoli. Mitotic activity was minimal. Hematoxylin-eosin stain, original magnification ×250.

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  • Identifying features of dendritic cells

    Dendritic CellsPhenotypeDisorder
    Indeterminate cellCD1a, S100, CD45, factor XIIIa-, no Birbeck granulesDendritic cell histiocytoma/indeterminate cell type
    Activated dendritic cellHLA-II membrane, fascin-mod, CD68, S100Dendritic cell histiocytoma/activated cell type
    Interdigitating dendritic cellFascin hi, S100 hi, CD45, CD83, DC-LAMP, CD14-, CD1a-, factor XIIIa-Dendritic cell hyperplasia and dendritic cell histiocytoma/interdigitating cell type
    Follicular dendritic cellCD21, CD35, Ki-M4, S100 variable, CD45-, fascinDendritic cell histiocytoma/follicular dendritic cell type
    Dermal dendrocytesCD68, CD45, fascin, factor XIIIa, S100-, CD1a-Xanthogranuloma type
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American Journal of Neuroradiology: 28 (10)
American Journal of Neuroradiology
Vol. 28, Issue 10
November 2007
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A.S. Abi-Ghanem, O. Uzuner, F.B. Askin, D.M. Yousem
Radiologic Findings in a Patient with Frontal Parafalcine Dendritic Cell Histiocytoma
American Journal of Neuroradiology Nov 2007, 28 (10) 1991-1992; DOI: 10.3174/ajnr.A0728

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Radiologic Findings in a Patient with Frontal Parafalcine Dendritic Cell Histiocytoma
A.S. Abi-Ghanem, O. Uzuner, F.B. Askin, D.M. Yousem
American Journal of Neuroradiology Nov 2007, 28 (10) 1991-1992; DOI: 10.3174/ajnr.A0728
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