Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • ASNR Foundation Special Collection
    • Most Impactful AJNR Articles
    • Photon-Counting CT
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • ASNR Foundation Special Collection
    • Most Impactful AJNR Articles
    • Photon-Counting CT
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR is seeking candidates for the AJNR Podcast Editor. Read the position description.

Research ArticleBRAIN

Combined 3T Diffusion Tensor Tractography and 1H-MR Spectroscopy in Motor Neuron Disease

M. Nelles, W. Block, F. Träber, U. Wüllner, H.H. Schild and H. Urbach
American Journal of Neuroradiology October 2008, 29 (9) 1708-1714; DOI: https://doi.org/10.3174/ajnr.A1201
M. Nelles
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
W. Block
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
F. Träber
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
U. Wüllner
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
H.H. Schild
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
H. Urbach
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. ↵
    Strong M, Rosenfeld J. Amyotrophic lateral sclerosis: a review of current concepts. Amyotroph Lateral Scler Other Motor Neuron Disord 2003;4:136–43
    CrossRefPubMed
  2. ↵
    Gordon PH, Cheng B, Katz IB, et al. The natural history of primary lateral sclerosis. Neurology 2006;66:647–53
    Abstract/FREE Full Text
  3. ↵
    Urban PP, Wicht S, Hopf HC. Sensitivity of transcranial magnetic stimulation of cortico-bulbar vs. cortico-spinal tract involvement in Amyotrophic Lateral Sclerosis (ALS). J Neurol 2001;248:850–55
    CrossRefPubMedWeb of Science
  4. ↵
    Buhler R, Magistris MR, Truffert A, et al. The triple stimulation technique to study central motor conduction to the lower limbs. Clin Neurophysiol 2001;112:938–49
    CrossRefPubMedWeb of Science
  5. ↵
    Brooks BR, Miller RG, Swash M, et al. El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord 2000;1:293–99
    CrossRefPubMedWeb of Science
  6. Cedarbaum JM, Stambler N, Malta E, et al. The ALSFRS-R: a revised ALS functional rating scale that incorporates assessments of respiratory function: BDNF ALS Study Group (Phase III). J Neurol Sci 1999;169:13–21
    CrossRefPubMedWeb of Science
  7. ↵
    Block W, Karitzky J, Traber F, et al. Proton magnetic resonance spectroscopy of the primary motor cortex in patients with motor neuron disease: subgroup analysis and follow-up measurements. Arch Neurol 1998;55:931–36
    CrossRefPubMedWeb of Science
  8. ↵
    Pohl C, Block W, Traber F, et al. Proton magnetic resonance spectroscopy and transcranial magnetic stimulation for the detection of upper motor neuron degeneration in ALS patients. J Neurol Sci 2001;190:21–27
    CrossRefPubMed
  9. ↵
    Pohl C, Block W, Karitzky J, et al. Proton magnetic resonance spectroscopy of the motor cortex in 70 patients with amyotrophic lateral sclerosis. Arch Neurol 2001;58:729–35
    CrossRefPubMedWeb of Science
  10. Ellis CM, Simmons A, Andrews C, et al. A proton magnetic resonance spectroscopic study in ALS: correlation with clinical findings. Neurology 1998;51:1104–09
    Abstract/FREE Full Text
  11. ↵
    Kalra S, Cashman NR, Genge A, et al. Recovery of N-acetylaspartate in corticomotor neurons of patients with ALS after riluzole therapy. Neuroreport 1998;9:1757–61
    PubMedWeb of Science
  12. ↵
    Cosottini M, Giannelli M, Siciliano G, et al. Diffusion-tensor MR imaging of corticospinal tract in amyotrophic lateral sclerosis and progressive muscular atrophy. Radiology 2005;237:258–64
    CrossRefPubMedWeb of Science
  13. Ellis CM, Simmons A, Jones DK, et al. Diffusion tensor MRI assesses corticospinal tract damage in ALS. Neurology 1999;53:1051–58
    Abstract/FREE Full Text
  14. Graham JM, Papadakis N, Evans J, et al. Diffusion tensor imaging for the assessment of upper motor neuron integrity in ALS. Neurology 2004;63:2111–19
    Abstract/FREE Full Text
  15. Hong YH, Lee KW, Sung JJ, et al. Diffusion tensor MRI as a diagnostic tool of upper motor neuron involvement in amyotrophic lateral sclerosis. J Neurol Sci 2004;227:73–78
    CrossRefPubMedWeb of Science
  16. ↵
    Jacob S, Finsterbusch J, Weishaupt JH, et al. Diffusion tensor imaging for long-term follow-up of corticospinal tract degeneration in amyotrophic lateral sclerosis. Neuroradiology 2003;45:598–600
    CrossRefPubMedWeb of Science
  17. ↵
    Sach M, Winkler G, Glauche V, et al. Diffusion tensor MRI of early upper motor neuron involvement in amyotrophic lateral sclerosis. Brain 2004;127:340–50
    Abstract/FREE Full Text
  18. Toosy AT, Werring DJ, Orrell RW, et al. Diffusion tensor imaging detects corticospinal tract involvement at multiple levels in amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry 2003;74:1250–57
    Abstract/FREE Full Text
  19. ↵
    Ulug AM, Grunewald T, Lin MT, et al. Diffusion tensor imaging in the diagnosis of primary lateral sclerosis. J Magn Reson Imaging 2004;19:34–39
    CrossRefPubMedWeb of Science
  20. ↵
    Aoki S, Iwata NK, Masutani Y, et al. Quantitative evaluation of the pyramidal tract segmented by diffusion tensor tractography: feasibility study in patients with amyotrophic lateral sclerosis. Radiat Med 2005;23:195–99
    PubMed
  21. ↵
    Wang S, Poptani H, Woo JH, et al. Amyotrophic lateral sclerosis: diffusion-tensor and chemical shift MR imaging at 3.0 T. Radiology 2006;239:831–38
    CrossRefPubMedWeb of Science
  22. ↵
    Yin H, Lim CC, Ma L, et al. Combined MR spectroscopic imaging and diffusion tensor MRI visualizes corticospinal tract degeneration in amyotrophic lateral sclerosis. J Neurol 2004;251:1249–54
    CrossRefPubMed
  23. ↵
    Mitsumoto H, Ulug AM, Pullman SL, et al. Quantitative objective markers for upper and lower motor neuron dysfunction in ALS. Neurology 2007;68:1402–10
    Abstract/FREE Full Text
  24. ↵
    Chan S, Kaufmann P, Shungu DC, et al. Amyotrophic lateral sclerosis and primary lateral sclerosis: evidence-based diagnostic evaluation of the upper motor neuron. Neuroimaging Clin N Am 2003;13:307–26
    CrossRefPubMedWeb of Science
  25. ↵
    Brooks BR. What are the implications of early diagnosis? Maintaining optimal health as long as possible. Neurology 1999;53:S43–S45
    PubMed
  26. ↵
    Brooks BR. Earlier is better: the benefits of early diagnosis. Neurology 1999;53:S53–S54
    PubMedWeb of Science
  27. ↵
    Goodin DS, Rowley HA, Olney RK. Magnetic resonance imaging in amyotrophic lateral sclerosis. Ann Neurol 1988;23:418–20
    CrossRefPubMedWeb of Science
  28. Udaka F, Sawada H, Seriu N, et al. MRI and SPECT findings in amyotrophic lateral sclerosis: demonstration of upper motor neurone involvement by clinical neuroimaging. Neuroradiology 1992;34:389–93
    CrossRefPubMed
  29. Cheung G, Gawel MJ, Cooper PW, et al. Amyotrophic lateral sclerosis: correlation of clinical and MR imaging findings. Radiology 1995;194:263–70
    PubMedWeb of Science
  30. Hofmann E, Ochs G, Pelzl A, et al. The corticospinal tract in amyotrophic lateral sclerosis: an MRI study. Neuroradiology 1998;40:71–75
    CrossRefPubMedWeb of Science
  31. ↵
    Hecht MJ, Fellner F, Fellner C, et al. MRI-FLAIR images of the head show corticospinal tract alterations in ALS patients more frequently than T2-, T1- and proton-density-weighted images J Neurol Sci 2001;186:37–44
    CrossRefPubMedWeb of Science
  32. ↵
    Hecht MJ, Fellner F, Fellner C, et al. Hyperintense and hypointense MRI signals of the precentral gyrus and corticospinal tract in ALS: a follow-up examination including FLAIR images. J Neurol Sci 2002;199:59–65
    CrossRefPubMed
  33. ↵
    Ishikawa K, Nagura H, Yokota T, et al. Signal loss in the motor cortex on magnetic resonance images in amyotrophic lateral sclerosis. Ann Neurol 1993;33:218–22
    CrossRefPubMed
  34. ↵
    Oba H, Araki T, Ohtomo K, et al. Amyotrophic lateral sclerosis: T2 shortening in motor cortex at MR imaging. Radiology 1993;189:843–46
    PubMedWeb of Science
  35. ↵
    Grosskreutz J, Kaufmann J, Fradrich J, et al. Widespread sensorimotor and frontal cortical atrophy in amyotrophic lateral sclerosis. BMC Neurol 2006;6:17
    CrossRefPubMed
  36. ↵
    Young S, Bystrov D, Netsch T, et al. Automated planning of MRI neuro scans. In: Reinhardt JM, Pluim JPW, eds. Medical Imaging 2006: Image Processing. San Diego, Calif, SPIE Medical Imaging;2006 :6144 (1),61441M-8
  37. ↵
    Naressi A, Couturier C, Devos JM, et al. Java-based graphical user interface for the MRUI quantitation package. MAGMA 2001;12:141–52
    CrossRefPubMed
  38. ↵
    Vanhamme L, van den BA, Van HS. Improved method for accurate and efficient quantification of MRS data with use of prior knowledge. J Magn Reson 1997;129:35–43
    CrossRefPubMedWeb of Science
  39. ↵
    Träber F, Block W, Lamerichs R, et al. 1H metabolite relaxation times at 3.0 tesla: measurements of T1 and T2 values in normal brain and determination of regional differences in transverse relaxation. J Magn Reson Imaging 2004;19:537–45
    CrossRefPubMedWeb of Science
  40. ↵
    Jaermann T, Crelier G, Pruessmann KP, et al. SENSE-DTI at 3 T. Magn Reson Med 2004;51:230–36
    CrossRefPubMedWeb of Science
  41. ↵
    Mori S, Kaufmann WE, Davatzikos C, et al. Imaging cortical association tracts in the human brain using diffusion-tensor-based axonal tracking. Magn Reson Med 2002;47:215–23
    CrossRefPubMedWeb of Science
  42. Mori S, Crain BJ, Chacko VP, et al. Three-dimensional tracking of axonal projections in the brain by magnetic resonance imaging. Ann Neurol 1999;45:265–69
    CrossRefPubMedWeb of Science
  43. ↵
    Stieltjes B, Kaufmann WE, van Zijl PC, et al. Diffusion tensor imaging and axonal tracking in the human brainstem. Neuroimage 2001;14:723–35
    CrossRefPubMedWeb of Science
  44. ↵
    Wakana S, Jiang H, Nagae-Poetscher LM, et al. Fiber tract-based atlas of human white matter anatomy. Radiology 2004;230:77–87
    CrossRefPubMedWeb of Science
  45. ↵
    Wang S, Melhem ER. Amyotrophic lateral sclerosis and primary lateral sclerosis: the role of diffusion tensor imaging and other advanced MR-based techniques as objective upper motor neuron markers. Ann N Y Acad Sci 2005;1064:61–77
    CrossRefPubMedWeb of Science
  46. ↵
    Wang S, Poptani H, Bilello M, et al. Diffusion tensor imaging in amyotrophic lateral sclerosis: volumetric analysis of the corticospinal tract. AJNR Am J Neuroradiol 2006;27:1234–38
    Abstract/FREE Full Text
  47. ↵
    Sage CA, Peeters RR, Gorner A, et al. Quantitative diffusion tensor imaging in amyotrophic lateral sclerosis. Neuroimage 2007;34:486–99
    CrossRefPubMedWeb of Science
  48. ↵
    Provenzale J. Amyotrophic lateral sclerosis (ALS). In: Osborn AG, ed. Diagnostic Imaging Brain. 3rd ed. Salt Lake City, Utah: Amirsys Inc;2005 :I/10:86–90
  49. ↵
    Karitzky J, Block W, Mellies JK, et al. Proton magnetic resonance spectroscopy in Kennedy syndrome. Arch Neurol 1999;56:1465–71
    CrossRefPubMedWeb of Science
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 29 (9)
American Journal of Neuroradiology
Vol. 29, Issue 9
October 2008
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Combined 3T Diffusion Tensor Tractography and 1H-MR Spectroscopy in Motor Neuron Disease
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
M. Nelles, W. Block, F. Träber, U. Wüllner, H.H. Schild, H. Urbach
Combined 3T Diffusion Tensor Tractography and 1H-MR Spectroscopy in Motor Neuron Disease
American Journal of Neuroradiology Oct 2008, 29 (9) 1708-1714; DOI: 10.3174/ajnr.A1201

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Combined 3T Diffusion Tensor Tractography and 1H-MR Spectroscopy in Motor Neuron Disease
M. Nelles, W. Block, F. Träber, U. Wüllner, H.H. Schild, H. Urbach
American Journal of Neuroradiology Oct 2008, 29 (9) 1708-1714; DOI: 10.3174/ajnr.A1201
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • Materials and Methods
    • Results
    • Discussion
    • Conclusion
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • High T2 Signal in Primary Lateral Sclerosis Supports the Topographic Distribution of Fibers in the Corpus Callosum: Assessing Disease in the Primary Motor Segment
  • The Present and the Future of Neuroimaging in Amyotrophic Lateral Sclerosis
  • Crossref (25)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • A review of magnetic resonance imaging and diffusion tensor imaging findings in mild traumatic brain injury
    M. E. Shenton, H. M. Hamoda, J. S. Schneiderman, S. Bouix, O. Pasternak, Y. Rathi, M.-A. Vu, M. P. Purohit, K. Helmer, I. Koerte, A. P. Lin, C.-F. Westin, R. Kikinis, M. Kubicki, R. A. Stern, R. Zafonte
    Brain Imaging and Behavior 2012 6 2
  • The neurochemical profile quantified by in vivo 1H NMR spectroscopy
    João M.N. Duarte, Hongxia Lei, Vladimír Mlynárik, Rolf Gruetter
    NeuroImage 2012 61 2
  • Impaired Structural Motor Connectome in Amyotrophic Lateral Sclerosis
    Esther Verstraete, Jan H. Veldink, Rene C. W. Mandl, Leonard H. van den Berg, Martijn P. van den Heuvel, Yong He
    PLoS ONE 2011 6 9
  • The Present and the Future of Neuroimaging in Amyotrophic Lateral Sclerosis
    F. Agosta, A. Chiò, M. Cosottini, N. De Stefano, A. Falini, M. Mascalchi, M.A. Rocca, V. Silani, G. Tedeschi, M. Filippi
    American Journal of Neuroradiology 2010 31 10
  • Diagnostic Accuracy of Diffusion Tensor Imaging in Amyotrophic Lateral Sclerosis
    Bradley R. Foerster, Ben A. Dwamena, Myria Petrou, Ruth C. Carlos, Brian C. Callaghan, Cristina L. Churchill, Mona A. Mohamed, Claudia Bartels, Michael Benatar, Laura Bonzano, Olga Ciccarelli, Mirco Cosottini, Cathy M. Ellis, Hannelore Ehrenreich, Nicola Filippini, Mizuki Ito, Sanjay Kalra, Elias R. Melhem, Timothy Pyra, Luca Roccatagliata, Joe Senda, Gen Sobue, Martin R. Turner, Eva L. Feldman, Martin G. Pomper
    Academic Radiology 2013 20 9
  • EFNS guidelines on the use of neuroimaging in the management of motor neuron diseases
    M. Filippi, F. Agosta, S. Abrahams, F. Fazekas, J. Grosskreutz, S. Kalra, J. Kassubek, V. Silani, M. R. Turner, J. C. Masdeu
    European Journal of Neurology 2010 17 4
  • Multimodal structural MRI in the diagnosis of motor neuron diseases
    Pilar M. Ferraro, Federica Agosta, Nilo Riva, Massimiliano Copetti, Edoardo Gioele Spinelli, Yuri Falzone, Gianni Sorarù, Giancarlo Comi, Adriano Chiò, Massimo Filippi
    NeuroImage: Clinical 2017 16
  • Integrated imaging of [11C]-PBR28 PET, MR diffusion and magnetic resonance spectroscopy 1H-MRS in amyotrophic lateral sclerosis
    Eva-Maria Ratai, Mohamad J. Alshikho, Nicole R. Zürcher, Marco L. Loggia, Catherine L. Cebulla, Paul Cernasov, Beverly Reynolds, Jennifer Fish, Raghav Seth, Suma Babu, Sabrina Paganoni, Jacob M. Hooker, Nazem Atassi
    NeuroImage: Clinical 2018 20
  • Multimodal MRI as a diagnostic biomarker for amyotrophic lateral sclerosis
    Bradley R. Foerster, Ruth C. Carlos, Ben A. Dwamena, Brian C. Callaghan, Myria Petrou, Richard A. E. Edden, Mona A. Mohamed, Robert C. Welsh, Peter B. Barker, Eva L. Feldman, Martin G. Pomper
    Annals of Clinical and Translational Neurology 2014 1 2
  • Prediction of Neurological Impairment in Cervical Spondylotic Myelopathy using a Combination of Diffusion MRI and Proton MR Spectroscopy
    Benjamin M. Ellingson, Noriko Salamon, Anthony J. Hardy, Langston T. Holly, Mohammed Shamji
    PLOS ONE 2015 10 10

More in this TOC Section

  • Optimal MRI Sequence for Identifying Occlusion Location in Acute Stroke: Which Value of Time-Resolved Contrast-Enhanced MRA?
  • Evaluating the Effects of White Matter Multiple Sclerosis Lesions on the Volume Estimation of 6 Brain Tissue Segmentation Methods
  • Quiet PROPELLER MRI Techniques Match the Quality of Conventional PROPELLER Brain Imaging Techniques
Show more BRAIN

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

Special Collections

  • AJNR Awards
  • ASNR Foundation Special Collection
  • Most Impactful AJNR Articles
  • Photon-Counting CT
  • Spinal CSF Leak Articles (Jan 2020-June 2024)

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire