Article Figures & Data
Figures
- Fig 1.
ADC measurement. In this 22-month-old girl, poorly differentiated chordoma is seen arising from the clivus (A), which shows minimal or no enhancement (B) and relatively low T2 intensity (C). Regions of interest were drawn at all available axial planes of the tumor on the ADC map (D) and along the entire boundary of the tumor soft tissue, avoiding areas of hemorrhage, necrosis, cyst, or calcification.
- Fig 2.
Sample ADC measurements in various tumors. Chondrosarcoma (A and D), classic chordoma (B), and poorly differentiated chordoma (C).
- Fig 3.
Enhancement patterns. Examples of enhancement patterns, mild to none (top), heterogeneous (middle), and solid (bottom) are shown in poorly differentiated chordomas (A and D), classic chordoma (B), and chondrosarcoma (C, E, and F).
- Fig 4.
Examples of T2 intensity features of the clival tumors. High T2 intensity of chondrosarcoma (A) and classic chordoma (B) are easily recognized. Contrast this with the low T2 intensity of poorly differentiated chordoma (C and D).
Tables
Entire Cohort (n = 19) Chondrosarcoma (n = 9) Classic Chordoma (n = 7) Poorly Differentiated Chordoma (n = 3) Age at diagnosis (yr) Median 36 37 36 7 Range 2–84 28–84 2–64 2–8 Sex Male 8 (42%) 3 (33%) 3 (43%) 2 (67%) Female 11 (58%) 6 (67%) 4 (57%) 1 (33%) Tumor location Clival 11 (58%) 4 (44%) 5 (71%) 3 (100%) Petroclival 7 (37%) 4 (44%) 2 (29%) 0 (0%) Pterygoid 1 (5%) 1 (11%) 0 (0%) 0 (0%) New or recurrent/residual New 16 (84%) 8 (89%) 5 (71%) 3 (100%) Recurrent/residual 3 (16%) 1 (11%) 2 (29%) 0 (0%) Tumor Mean ADC (Median) Minimum ADC (Median) Maximum ADC (Median) Chondrosarcoma (n = 9) 2051 ± 262 (1977) 1488 ± 360 (1352) 2503 ± 512 (2392) Classic Chordoma (n = 7) 1474 ± 117 (1460) 905 ± 118 (860) 2199 ± 255 (2217) Poorly Differentiated Chordoma (n = 3) 875 ± 100 (871) 491 ± 210 (469) 1503 ± 127 (1557) Tumor T2 Hypointensity >90% Enhancement Clival Location Chondrosarcoma (n = 9) 0 (0%) 5 (56%) 4 (44%) Classic chordoma (n = 7) 0 (0%) 1 (14%) 4 (57%) Poorly differentiated chordoma (n = 3) 3 (100%) 0 (0%) 3 (100%)
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