Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • ASNR Foundation Special Collection
    • Most Impactful AJNR Articles
    • Photon-Counting CT
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • ASNR Foundation Special Collection
    • Most Impactful AJNR Articles
    • Photon-Counting CT
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR is seeking candidates for the AJNR Podcast Editor. Read the position description.

Research ArticleHead & Neck

Diffusion-Weighted MRI: Distinction of Skull Base Chordoma from Chondrosarcoma

K.W. Yeom, R.M. Lober, B.C. Mobley, G. Harsh, H. Vogel, R. Allagio, M. Pearson, M.S.B. Edwards and N.J. Fischbein
American Journal of Neuroradiology May 2013, 34 (5) 1056-1061; DOI: https://doi.org/10.3174/ajnr.A3333
K.W. Yeom
aFrom the Departments of Radiology (K.W.Y., N.J.F.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
R.M. Lober
bNeurosurgery (R.M.L., G.H., M.S.B.E.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
B.C. Mobley
dDepartments of Pathology (B.C.M.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
G. Harsh
bNeurosurgery (R.M.L., G.H., M.S.B.E.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
H. Vogel
cPathology (H.V.), Stanford University, Palo Alto, California
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
R. Allagio
fDepartment of Pathology (R.A.), University of Padova, Padova, Italy.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. Pearson
eNeurosurgery (M.P.), Vanderbilt University Medical Center, Nashville, Tennessee
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M.S.B. Edwards
bNeurosurgery (R.M.L., G.H., M.S.B.E.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
N.J. Fischbein
aFrom the Departments of Radiology (K.W.Y., N.J.F.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. 1.↵
    Central Brain Tumor Registry of the United States. Statistical Report: Primary Brain Tumors in the United States, 1997–2001. Hinsdale, Illinois: Central Brain Tumor Registry of the United States
  2. 2.↵
    1. Heffelfinger MJ,
    2. Dahlin DC,
    3. MacCarty CS,
    4. et al
    . Chordomas and cartilaginous tumors of the skull base. Cancer 1973;32:410–20
    CrossRefPubMedWeb of Science
  3. 3.↵
    1. Almefty K,
    2. Pravdenkova S,
    3. Colli BO,
    4. et al
    . Chordoma and chondrosarcoma: similar, but quite different, skull base tumors. Cancer 2007;110:2456–67
  4. 4.↵
    1. Cho YH,
    2. Kim JH,
    3. Khang SK,
    4. et al
    . Chordomas and chondrosarcomas of the skull base: comparative analysis of clinical results in 30 patients. Neurosurg Rev 2008;31:35–43
    PubMed
  5. 5.↵
    1. Burrow JF,
    2. Stewart MJ
    . Original papers: malignant spheno-occipital chordoma. J Neurol Psychopathol 1923;15:205–17
  6. 6.↵
    1. Pamir MN,
    2. Ozduman K
    . Analysis of radiological features relative to histopathology in 42 skull-base chordomas and chondrosarcomas. Eur J Radiol 2006;58:461–70
    CrossRefPubMed
  7. 7.↵
    1. Fletcher CDM,
    2. Unni KK,
    3. Mertens F
    1. Mirra JM,
    2. Nelson SD,
    3. Della Rocca C,
    4. et al
    . Chordoma. In: Fletcher CDM, Unni KK, Mertens F, eds. World Health Organization Classification of Tumours: Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon, France: IARC Press; 2002:315–17
  8. 8.↵
    1. Hoch BL,
    2. Nielsen GP,
    3. Liebsch NJ,
    4. et al
    . Base of skull chordomas in children and adolescents: a clinicopathologic study of 73 cases. Am J Surg Pathol 2006;30:811–18
    CrossRefPubMed
  9. 9.↵
    1. Coffin CM,
    2. Swanson PE,
    3. Wick MR,
    4. et al
    . Chordoma in childhood and adolescence: a clinicopathologic analysis of 12 cases. Arch Pathol Lab Med 1993;117:927–33
    PubMed
  10. 10.↵
    1. Mobley BC,
    2. McKenney JK,
    3. Bangs CD,
    4. et al
    . Loss of SMARCB1/INI1 expression in poorly differentiated chordomas. Acta Neuropathol 2010;120:745–53
    CrossRefPubMedWeb of Science
  11. 11.↵
    1. Fletcher CDM,
    2. Unni KK,
    3. Mertens F
    1. Bertoni F,
    2. Bacchini P,
    3. Hogendoorn PC
    . Chondrosarcoma. In: Fletcher CDM, Unni KK, Mertens F, eds. World Health Organization Classification of Tumours: Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon, France: IARC Press; 2002:247–51
  12. 12.↵
    1. Oot RF,
    2. Melville GE,
    3. New PF,
    4. et al
    . The role of MR and CT in evaluating clival chordomas and chondrosarcomas. AJR Am J Roentgenol 1988;151:567–75
    PubMed
  13. 13.↵
    1. Bourgouin PM,
    2. Tampieri D,
    3. Robitaille Y,
    4. et al
    . Low-grade myxoid chondrosarcoma of the base of the skull: CT, MR, and histopathology. J Comput Assist Tomogr 1992;16:268–73
    PubMedWeb of Science
  14. 14.↵
    1. Sugahara T,
    2. Korogi Y,
    3. Kochi M,
    4. et al
    . Usefulness of diffusion-weighted MRI with echo-planar technique in evaluation of cellularity in gliomas. J Mag Res Imaging 1999;9:53–60
    CrossRefPubMedWeb of Science
  15. 15.↵
    1. Guo AC,
    2. Cummings TJ,
    3. Dash RC,
    4. et al
    . Lymphomas and high-grade astrocytomas: Comparison of water diffusibility and histologic characteristics. Radiology 2002;224:177–83
    CrossRefPubMedWeb of Science
  16. 16.↵
    1. Rumboldt Z,
    2. Camacho DL,
    3. Lake D,
    4. et al
    . Apparent diffusion coefficients for differentiation of cerebellar tumors in children. AJNR Am J Neuroradiol 2006;27:1362–69
    Abstract/FREE Full Text
  17. 17.↵
    1. Le Bihan D,
    2. Breton E,
    3. Lallemand D,
    4. et al
    . MR imaging of intravoxel incoherent motions: Application to diffusion and perfusion in neurologic disorders. Radiology 1986;161:401–07
    CrossRefPubMedWeb of Science
  18. 18.↵
    1. Filippi CG,
    2. Edgar MA,
    3. Ulug AM,
    4. et al
    . Appearance of meningiomas on diffusion-weighted images: correlating diffusion constants with histopathologic findings. AJNR Am J Neuroradiol 2001;22:65–72
    Abstract/FREE Full Text
  19. 19.↵
    1. Lichtenstein L,
    2. Jaffe HL
    . Chondrosarcoma of bone. Am J Pathol 1943;19:553–89
    PubMed
  20. 20.↵
    1. Dahlin DC,
    2. MacCarty CS
    . Chordoma. Cancer 1952;5:1170–78
    CrossRefPubMedWeb of Science
  21. 21.↵
    1. Evans HL,
    2. Ayala AG,
    3. Romsdahl MM
    . Prognostic factors in chondrosarcoma of bone: a clinicopathologic analysis with emphasis on histologic grading. Cancer 1977;40:818–31
    CrossRefPubMedWeb of Science
  22. 22.↵
    1. Hayashida Y,
    2. Hirai T,
    3. Yakushiji T,
    4. et al
    . Evaluation of diffusion-weighted imaging for the differential diagnosis of poorly contrast-enhanced and T2-prolonged bone masses: initial experience. J Magn Reson Imaging 2006;23:377–82
    CrossRefPubMed
  23. 23.↵
    1. Ginat DT,
    2. Mangla R,
    3. Yeaney G,
    4. et al
    . Diffusion-weighted imaging for differentiating benign from malignant skull lesions and correlation with cell density. AJR Am J Roentgenol 2012:198:W597–601
    CrossRefPubMed
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 34 (5)
American Journal of Neuroradiology
Vol. 34, Issue 5
1 May 2013
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Diffusion-Weighted MRI: Distinction of Skull Base Chordoma from Chondrosarcoma
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
K.W. Yeom, R.M. Lober, B.C. Mobley, G. Harsh, H. Vogel, R. Allagio, M. Pearson, M.S.B. Edwards, N.J. Fischbein
Diffusion-Weighted MRI: Distinction of Skull Base Chordoma from Chondrosarcoma
American Journal of Neuroradiology May 2013, 34 (5) 1056-1061; DOI: 10.3174/ajnr.A3333

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Diffusion-Weighted MRI: Distinction of Skull Base Chordoma from Chondrosarcoma
K.W. Yeom, R.M. Lober, B.C. Mobley, G. Harsh, H. Vogel, R. Allagio, M. Pearson, M.S.B. Edwards, N.J. Fischbein
American Journal of Neuroradiology May 2013, 34 (5) 1056-1061; DOI: 10.3174/ajnr.A3333
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATION:
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Acknowledgments
    • Footnotes
    • References
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • PubMed
  • Google Scholar

Cited By...

  • Time-Saving 3D MR Imaging Protocols with Millimeter and Submillimeter Isotropic Spatial Resolution for Face and Neck Imaging as Implemented at a Single-Site Major Referral Center
  • Differentiation of Skull Base Chondrosarcomas, Chordomas, and Metastases: Utility of DWI and Dynamic Contrast-Enhanced Perfusion MR Imaging
  • Exophytic Lumbar Vertebral Body Mass in an Adult with Back Pain
  • MRI Signal Intensity and Electron Ultrastructure Classification Predict the Long-Term Outcome of Skull Base Chordomas
  • Preoperative MR Imaging to Differentiate Chordoid Meningiomas from Other Meningioma Histologic Subtypes
  • Prognostic Implications of Gadolinium Enhancement of Skull Base Chordomas
  • Role of the Apparent Diffusion Coefficient as a Predictor of Tumor Progression in Patients with Chordoma
  • Chordoid Meningioma: Differentiating a Rare World Health Organization Grade II Tumor from Other Meningioma Histologic Subtypes Using MRI
  • Differentiation of Skull Base Chordomas from Chondrosarcomas by Diffusion-Weighted MRI
  • Crossref (129)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Building a global consensus approach to chordoma: a position paper from the medical and patient community
    Silvia Stacchiotti, Josh Sommer
    The Lancet Oncology 2015 16 2
  • Surgery of the lateral skull base: a 50-year endeavour
    E. Zanoletti, A. Mazzoni, A. Martini, R. V. Abbritti, R. Albertini, E. Alexandre, V. Baro, S. Bartolini, D. Bernardeschi, R. Bivona, M. Bonali, I. Borghesi, D. Borsetto, R. Bovo, M. Breun, F. Calbucci, M. L. Carlson, A. Caruso, P. Cayé-Thomasen, D. Cazzador, P. -O. Champagne, R. Colangeli, G. Conte, D. D’Avella, G. Danesi, L. Deantonio, L. Denaro, F. Di Berardino, R. Draghi, F. H. Ebner, N. Favaretto, G. Ferri, A. Fioravanti, S. Froelich, A. Giannuzzi, L. Girasoli, B. R. Grossardt, M. Guidi, R. Hagen, S. Hanakita, D. G. Hardy, V. C. Iglesias, S. Jefferies, H. Jia, M. Kalamarides, I. N. Kanaan, M. Krengli, A. Landi, L. Lauda, D. Lepera, S. Lieber, S. L. K. Lloyd, A. Lovato, F. Maccarrone, R. Macfarlane, J. Magnan, L. Magnoni, D. Marchioni, J. P. Marinelli, G. Marioni, V. Mastronardi, C. Matthies, D. A. Moffat, S. Munari, M. Nardone, R. Pareschi, C. Pavone, E. Piccirillo, G. Piras, L. Presutti, G. Restivo, M. Reznitsky, E. Roca, A. Russo, M. Sanna, L. Sartori, M. Scheich, W. Shehata-Dieler, D. Soloperto, F. Sorrentino, O. Sterkers, A. Taibah, M. Tatagiba, G. Tealdo, D. Vlad, H. Wu, D. Zanetti
    Acta Otorhinolaryngologica Italica 2019 39 3, SUPPLEMENT 1
  • Skull Base Chordomas and Chondrosarcomas
    Natalia Kremenevski, Sven-Martin Schlaffer, Roland Coras, Thomas Mehari Kinfe, Thomas Graillon, Michael Buchfelder
    Neuroendocrinology 2020 110 9-10
  • Diffusion-weighted MRI derived apparent diffusion coefficient identifies prognostically distinct subgroups of pediatric diffuse intrinsic pontine glioma
    Robert M. Lober, Yoon-Jae Cho, Yujie Tang, Patrick D. Barnes, Michael S. Edwards, Hannes Vogel, Paul G. Fisher, Michelle Monje, Kristen W. Yeom
    Journal of Neuro-Oncology 2014 117 1
  • Radiomic analysis of multiparametric magnetic resonance imaging for differentiating skull base chordoma and chondrosarcoma
    Longfei Li, Ke Wang, Xiujian Ma, Zhenyu Liu, Shuo Wang, Jiang Du, Kaibing Tian, Xuezhi Zhou, Wei wei, Kai Sun, Yusong Lin, Zhen Wu, Jie Tian
    European Journal of Radiology 2019 118
  • State-of-the-Art Imaging in Human Chordoma of the Skull Base
    Rene G. C. Santegoeds, Yasin Temel, Jan C. Beckervordersandforth, Jacobus J. Van Overbeeke, Christianne M. Hoeberigs
    Current Radiology Reports 2018 6 5
  • Sellar and Parasellar Imaging
    Carlos Zamora, Mauricio Castillo
    Neurosurgery 2017 80 1
  • Primary Skull Base Chondrosarcomas: A Systematic Review
    Paolo Palmisciano, Ali S. Haider, Mohammadmahdi Sabahi, Chibueze D. Nwagwu, Othman Bin Alamer, Gianluca Scalia, Giuseppe E. Umana, Aaron A. Cohen-Gadol, Tarek Y. El Ahmadieh, Kenny Yu, Omar N. Pathmanaban
    Cancers 2021 13 23
  • Benign and malignant diseases of the clivus
    A. Neelakantan, A.K. Rana
    Clinical Radiology 2014 69 12
  • Is there a role for conventional MRI and MR diffusion-weighted imaging for distinction of skull base chordoma and chondrosarcoma?
    Uta Müller, Rahel A Kubik-Huch, Carmen Ares, Eugen B Hug, Roland Löw, Antonios Valavanis, Frank J Ahlhelm
    Acta Radiologica 2016 57 2

More in this TOC Section

  • Chondrosarcoma vs Synovial Chondromatosis: Imaging
  • WHO Classification Update: Nasal&Skull Base Tumors
  • Peritumoral Signal in Vestibular Schwannomas
Show more HEAD & NECK

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

Special Collections

  • AJNR Awards
  • ASNR Foundation Special Collection
  • Most Impactful AJNR Articles
  • Photon-Counting CT
  • Spinal CSF Leak Articles (Jan 2020-June 2024)

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire