Table of Contents
Editorials
Perspectives
Editorials
Review Articles
Expedited Publication
- WEB-DL Endovascular Treatment of Wide-Neck Bifurcation Aneurysms: Short- and Midterm Results in a European Study
Short- and midterm results of endovascular aneurysm treatment with the new WEB-DL device were assessed in 45 patients from 12 European centers. Of these, 42 aneurysms were unruptured and most were located either in the MCA bifurcation or the posterior circulation. Adequate occlusion was observed in 81% and 90% of aneurysms at 6 and 13 months, respectively. Results suggest that WEB endovascular treatment of wide-neck bifurcation aneurysms offers stable occlusion in a class of aneurysms that are historically unstable.
Methodologic Perspectives
Patient Safety
Genetics Vignette
Brain
- Appropriate Use of CT Perfusion following Aneurysmal Subarachnoid Hemorrhage: A Bayesian Analysis Approach
These investigators evaluated the test characteristics of CTP in patients with SAH for detection of delayed cerebral ischemia. Ninety-seven patients were assessed with CTP for ischemia and with DSA for vasospasm. The authors concluded that positive CTP findings identified patients who should be carefully considered for induced hypertension, hypervolemia, and hemodilution and/or intra-arterial therapy while negative CTP findings are useful in guiding a no-treatment decision.
- Evaluation of Common Structural Brain Changes in Aging and Alzheimer Disease with the Use of an MRI-Based Brain Atrophy and Lesion Index: A Comparison Between T1WI and T2WI at 1.5T and 3T
This study assesses the usefulness of a set of established structural findings in Alzheimer disease with various MRI sequences at 2 different field strengths in 127 subjects. Scores of atrophy and lesion burden were reliable across sequences and unit strength and were lowest in individuals with cognitive impairment, higher in those with Alzheimer disease, and also correlated with age, cognitive performance, and amyloid-β test. Although the results were slightly better at 3T, the authors concluded that even at 1.5T scores were reliable.
Interventional
- Complications of Endovascular Treatment for Acute Stroke in the SWIFT Trial with Solitaire and Merci Devices
The safety of 2 devices to treat acute ischemic stroke was evaluated in 144 patients with special attention paid to complications such as cerebral hemorrhage, SAH, air emboli, vessel dissections, major groin complications, and emboli in new territories. Fewer endovascular complications occurred after treatment with the Solitaire device when compared with the Merci, particularly with respect to symptomatic cerebral hemorrhage.
Commentary
- Coiling of Large and Giant Aneurysms: Complications and Long-Term Results of 334 Cases
The long-term complications of coil treatment of giant intracranial aneurysms were assessed in 334 instances when treatment consisted of only coiling (225), stent-assisted coiling (88), parent vessel occlusion (14), or balloon-assisted coiling (7). The authors concluded that coiling of large and giant aneurysms has reasonable safety profiles with good clinical outcomes, but aneurysm reopening was common. Stent-assisted coiling had lower recurrence, retreatment, and new or recurrent hemorrhage rates with no additional morbidity compared with conventional coiling. Aneurysm size was a major determinant of recanalization, retreatment, new or recurrent hemorrhage, and poor outcome.
Extracranial Vascular
Head & Neck
Pediatrics
- Left Hemisphere Diffusivity of the Arcuate Fasciculus: Influences of Autism Spectrum Disorder and Language Impairment
The authors used DTI measurements of the arcuate fasciculus in 14 children with language impairment, in 16 autistic children with language impairment, 18 autistic children without language impairment, and 25 controls. Although white matter abnormalities appeared similar in language impairment and autism spectrum disorder when examining broad white matter measures, detailed analysis indicated different mechanisms for the white matter microstructural anomalies associated with these disorders.
