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Research ArticleBrain

Pretreatment Advanced Imaging in Patients with Stroke Treated with IV Thrombolysis: Evaluation of a Multihospital Data Base

J.S. McDonald, J. Fan, D.F. Kallmes and H.J. Cloft
American Journal of Neuroradiology March 2014, 35 (3) 478-481; DOI: https://doi.org/10.3174/ajnr.A3797
J.S. McDonald
aFrom the Departments of Radiology (J.S.M., D.F.K., H.J.C.)
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J. Fan
bHealth Sciences Research (J.F.)
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D.F. Kallmes
aFrom the Departments of Radiology (J.S.M., D.F.K., H.J.C.)
cNeurosurgery (D.F.K., H.J.C.), Mayo Clinic, Rochester, Minnesota.
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H.J. Cloft
aFrom the Departments of Radiology (J.S.M., D.F.K., H.J.C.)
cNeurosurgery (D.F.K., H.J.C.), Mayo Clinic, Rochester, Minnesota.
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    Fig 1.

    Trends in the use of head CT and advanced imaging in patients treated with IV thrombolysis from 2008 to 2011. Patients who received only head CT (blue line), head CT with CT angiography (red line), head CT with CT perfusion (green line), or head CT with MR imaging (purple line) are shown.

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    Table 1:

    Outcome incidences by imaging subgroup

    CT GroupCTA GroupCTP GroupMR Group
    In-hospital mortality748/7305 (10.2%)241/2359 (12.4%)105/848 (12.4%)119/1917 (6.2%)
    Discharge to long-term care3170/7305 (43%)975/2359 (41%)399/848 (47%)828/1917 (43%)
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    Table 2:

    Patient outcomes following logistic regression analysis

    Odds Ratio (95% CI)P Value
    In-hospital mortality
        Full model
            CT1.00 (reference)–
            CTA1.00 (0.83–1.21).99
            CTP1.17 (0.93–1.47).20
            MRI0.64 (0.52–0.79)<.0001
        Reduced model
            CT1.00 (reference)–
            CTA1.03 (0.86–1.24).75
            CTP1.14 (0.92–1.40).22
            MRI0.65 (0.53–0.79)<.0001
    Discharge to long-term care
        Full model
            CT1.00 (reference)–
            CTA0.95 (0.83–1.09).31
            CTP1.17 (0.96–1.43).0412
            MRI1.14 (1.01–1.28).0177
        Reduced model
            CT1.00 (reference)–
            CTA0.89 (0.66–1.18).59
            CTP1.33 (1.00–1.77).12
            MRI1.15 (0.73–1.83).0471
    • Note:— –indicates no P value was calculated for the CT reference group.

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American Journal of Neuroradiology: 35 (3)
American Journal of Neuroradiology
Vol. 35, Issue 3
1 Mar 2014
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Cite this article
J.S. McDonald, J. Fan, D.F. Kallmes, H.J. Cloft
Pretreatment Advanced Imaging in Patients with Stroke Treated with IV Thrombolysis: Evaluation of a Multihospital Data Base
American Journal of Neuroradiology Mar 2014, 35 (3) 478-481; DOI: 10.3174/ajnr.A3797

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Pretreatment Advanced Imaging in Patients with Stroke Treated with IV Thrombolysis: Evaluation of a Multihospital Data Base
J.S. McDonald, J. Fan, D.F. Kallmes, H.J. Cloft
American Journal of Neuroradiology Mar 2014, 35 (3) 478-481; DOI: 10.3174/ajnr.A3797
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    Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 2020 47 6
  • Neuroimaging in acute ischemic stroke: Trends, disparities, and clinical impact
    Jason J. Wang, Jeffrey M. Katz, Artem Boltyenkov, Gabriela Martinez, Joseph O'Hara, Michele Gribko, Ankur Pandya, Elizabeth Rula, Pina Sanelli
    European Journal of Radiology 2022 154
  • Is CT perfusion helpful in the treatment allocation of patients with acute ischemic stroke? An expert-opinion analysis
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