Article Figures & Data
Figures
- Fig 1.
A and B, Brain segmentation process of the 9-month template is shown; C, 4-month T1 image; D, corresponding atlas after mathematica transformation. E, CBF image; F, CBF image with the atlas overlaid to demonstrate how well they are registered; G, the 8 segments projected onto the cortical surface.
- Fig 2.
Regional differences in CBF. Although there were no significant differences within the 3 higher flow regions (sensorimotor, parieto-occipital, and inferior-occipital; P = .43) or within the 3 lower flow regions (subgenual, orbito-frontal, and dorsolateral prefrontal; P = .15), mean CBF between the high and low groups was highly significant. The mixed model fit age in a continuous manner, but, for illustrative purposes, age is split at the median. Horizontal dotted line is the median CBF value across all regions and ages.
- Fig 3.
Regions with CBF above study population median are shown in shades of red and those regions with CBF below the median are shown in shades of blue. Darker color indicates greater deviation from the median flow. Thus, the sensorimotor (SM) region had the highest flow above the median and the dorsolateral prefrontal (DLPF) region had the lowest flow below the median.
- Fig 4.
Cerebral blood flow versus age within each region; ρ is Spearman rank correlation coefficient.
Tables
Demographic information for study subjects
Total (n = 61) Male (n = 37) (61%) Female (n = 24) (39%) Birth weight, g 3,294.95 ± 432.2 3,363.6 ± 408.8 3,190.5 ± 554.6 Gestational age, wk 39.2 ± 1.4 37.3 ± 9.1 38.9 ± 1.5 Age at scanning, d 123.6 ± 13 122.3 ± 12.6 125.5 ± 13.4a Sex, % girlsa 39% Ethnicitya White 15 (24.59%) 8 (21.62%) 7 (29.16%) Black 1 (1.64%) 1 (2.70%) 0 (0%) Hispanic 34 (55.73%) 21 (56.75%) 13 (54.16%) Native American 3 (4.92%) 2 (5.40%) 1 (4.16%) Other 4 (6.55%) 3 (8.10%) 1 (4.16%) Unknown 4 (6.55%) 2 (5.40%) 2 (8.33%) Note:—Values are depicted as means ± standard deviations unless otherwise indicated.
↵a P < .05.
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