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Research ArticleExtracranial Vascular

CT Angiographic Features of Symptom-Producing Plaque in Moderate-Grade Carotid Artery Stenosis

A. Gupta, E.E. Mtui, H. Baradaran, G. Salama, A. Pandya, H. Kamel, A. Giambrone and P.C. Sanelli
American Journal of Neuroradiology February 2015, 36 (2) 349-354; DOI: https://doi.org/10.3174/ajnr.A4098
A. Gupta
aFrom the Departments of Radiology (A. Gupta, E.E.M., H.B., G.S., A.P., P.C.S.)
dBrain and Mind Research Institute (A. Gupta, H.K.), Weill Cornell Medical College, New York, New York.
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E.E. Mtui
aFrom the Departments of Radiology (A. Gupta, E.E.M., H.B., G.S., A.P., P.C.S.)
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H. Baradaran
aFrom the Departments of Radiology (A. Gupta, E.E.M., H.B., G.S., A.P., P.C.S.)
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G. Salama
aFrom the Departments of Radiology (A. Gupta, E.E.M., H.B., G.S., A.P., P.C.S.)
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A. Pandya
aFrom the Departments of Radiology (A. Gupta, E.E.M., H.B., G.S., A.P., P.C.S.)
cHealthcare Policy and Research (A.P., A. Giambrone, P.C.S.)
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H. Kamel
bNeurology (H.K.)
dBrain and Mind Research Institute (A. Gupta, H.K.), Weill Cornell Medical College, New York, New York.
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A. Giambrone
cHealthcare Policy and Research (A.P., A. Giambrone, P.C.S.)
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P.C. Sanelli
aFrom the Departments of Radiology (A. Gupta, E.E.M., H.B., G.S., A.P., P.C.S.)
cHealthcare Policy and Research (A.P., A. Giambrone, P.C.S.)
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REFERENCES

  1. 1.↵
    1. Rothwell PM,
    2. Eliasziw M,
    3. Gutnikov SA, et al
    . Analysis of pooled data from the randomised controlled trials of endarterectomy for symptomatic carotid stenosis. Lancet 2003;361:107–16
    CrossRefPubMedWeb of Science
  2. 2.↵
    1. Abbott AL
    . Medical (nonsurgical) intervention alone is now best for prevention of stroke associated with asymptomatic severe carotid stenosis: results of a systematic review and analysis. Stroke 2009;40:e573–83
    Abstract/FREE Full Text
  3. 3.↵
    1. Raman G,
    2. Moorthy D,
    3. Hadar N, et al
    . Management strategies for asymptomatic carotid stenosis: a systematic review and meta-analysis. Ann Intern Med 2013;158:676–85
    CrossRefPubMed
  4. 4.↵
    1. Caplan LR,
    2. Hennerici M
    . Impaired clearance of emboli (washout) is an important link between hypoperfusion, embolism, and ischemic stroke. Arch Neurol 1998;55:1475–82
    CrossRefPubMedWeb of Science
  5. 5.↵
    1. Hosseini AA,
    2. Kandiyil N,
    3. Macsweeney ST, et al
    . Carotid plaque hemorrhage on magnetic resonance imaging strongly predicts recurrent ischemia and stroke. Ann Neurol 2013;73:774–84
    CrossRefPubMed
  6. 6.↵
    1. Derdeyn CP
    . Mechanisms of ischemic stroke secondary to large artery atherosclerotic disease. Neuroimaging Clin N Am 2007;17:303–11, vii–viii.
    CrossRefPubMedWeb of Science
  7. 7.↵
    1. Gupta A,
    2. Chazen JL,
    3. Hartman M, et al
    . Cerebrovascular reserve and stroke risk in patients with carotid stenosis or occlusion: a systematic review and meta-analysis. Stroke 2012;43:2884–91
    Abstract/FREE Full Text
  8. 8.↵
    1. Morgenstern LB,
    2. Fox AJ,
    3. Sharpe BL, et al
    . The risks and benefits of carotid endarterectomy in patients with near occlusion of the carotid artery: North American Symptomatic Carotid Endarterectomy Trial (NASCET) group. Neurology 1997;48:911–15
    CrossRef
  9. 9.↵
    1. den Hartog AG,
    2. Bovens SM,
    3. Koning W, et al
    . Current status of clinical magnetic resonance imaging for plaque characterisation in patients with carotid artery stenosis. Eur J Vasc Endovasc Surg 2013;45:7–21
    CrossRefPubMed
  10. 10.↵
    1. Cai JM,
    2. Hatsukami TS,
    3. Ferguson MS, et al
    . Classification of human carotid atherosclerotic lesions with in vivo multicontrast magnetic resonance imaging. Circulation 2002;106:1368–73
    Abstract/FREE Full Text
  11. 11.↵
    1. Stary HC,
    2. Chandler AB,
    3. Dinsmore RE, et al
    . A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis: a report from the committee on vascular lesions of the council on arteriosclerosis, American Heart Association. Circulation 1995;92:1355–74
    Abstract/FREE Full Text
  12. 12.↵
    1. Trelles M,
    2. Eberhardt KM,
    3. Buchholz M, et al
    . CTA for screening of complicated atherosclerotic carotid plaque–American Heart Association type VI lesions as defined by MRI. AJNR Am J Neuroradiol 2013;34:2331–37
    Abstract/FREE Full Text
  13. 13.↵
    1. Gupta A,
    2. Baradaran H,
    3. Kamel H, et al
    . Evaluation of computed tomography angiography plaque thickness measurements in high-grade carotid artery stenosis. Stroke 2014;45:740–45
    Abstract/FREE Full Text
  14. 14.↵
    1. Fox AJ,
    2. Symons SP,
    3. Aviv RI, et al
    . Falsely claiming use of NASCET percentage stenosis method. Radiology 2009;253:574–45, author reply 575
    CrossRefPubMed
  15. 15.↵
    1. Fox AJ
    . How to measure carotid stenosis. Radiology 1993;186:316–18
    CrossRefPubMedWeb of Science
  16. 16.↵
    1. Easton JD,
    2. Saver JL,
    3. Albers GW, et al
    . Definition and evaluation of transient ischemic attack: a scientific statement for healthcare professionals from the American Heart Association/American Stroke Association Stroke Council; Council on Cardiovascular Surgery and Anesthesia; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular Nursing; and the Interdisciplinary Council on Peripheral Vascular Disease—the American Academy of Neurology affirms the value of this statement as an educational tool for neurologists. Stroke 2009;40:2276–93
    Abstract/FREE Full Text
  17. 17.↵
    1. de Weerd M,
    2. Greving JP,
    3. Hedblad B, et al
    . Prevalence of asymptomatic carotid artery stenosis in the general population: an individual participant data meta-analysis. Stroke 2010;41:1294–97
    Abstract/FREE Full Text
  18. 18.↵
    1. Wintermark M,
    2. Jawadi SS,
    3. Rapp JH, et al
    . High-resolution CT imaging of carotid artery atherosclerotic plaques. AJNR Am J Neuroradiol 2008;29:875–82
    Abstract/FREE Full Text
  19. 19.↵
    1. Wintermark M,
    2. Arora S,
    3. Tong E, et al
    . Carotid plaque computed tomography imaging in stroke and nonstroke patients. Ann Neurol 2008;64:149–57
    CrossRefPubMed
  20. 20.↵
    1. U-King-Im JM,
    2. Fox AJ,
    3. Aviv RI, et al
    . Characterization of carotid plaque hemorrhage: a CT angiography and MR intraplaque hemorrhage study. Stroke 2010;41:1623–29
    Abstract/FREE Full Text
  21. 21.↵
    1. Walker LJ,
    2. Ismail A,
    3. McMeekin W, et al
    . Computed tomography angiography for the evaluation of carotid atherosclerotic plaque: correlation with histopathology of endarterectomy specimens. Stroke 2002;33:977–81
    Abstract/FREE Full Text
  22. 22.↵
    1. Romero JM,
    2. Babiarz LS,
    3. Forero NP, et al
    . Arterial wall enhancement overlying carotid plaque on CT angiography correlates with symptoms in patients with high grade stenosis. Stroke 2009;40:1894–96
    Abstract/FREE Full Text
  23. 23.↵
    1. Hokari M,
    2. Kuroda S,
    3. Yasuda H, et al
    . Lumen morphology in mild-to-moderate internal carotid artery stenosis correlates with neurological symptoms. J Neuroimaging 2011;21:348–54
    CrossRefPubMed
  24. 24.↵
    1. El-Barghouty NM,
    2. Levine T,
    3. Ladva S, et al
    . Histological verification of computerised carotid plaque characterisation. Eur J Vasc Endovasc Surg 1996;11:414–16
    CrossRefPubMedWeb of Science
  25. 25.↵
    1. Gupta A,
    2. Baradaran H,
    3. Schweitzer AD, et al
    . Carotid plaque MRI and stroke risk: a systematic review and meta-analysis. Stroke 2013;44:3071–77
    Abstract/FREE Full Text
  26. 26.↵
    1. Kwee RM
    . Systematic review on the association between calcification in carotid plaques and clinical ischemic symptoms. J Vasc Surg 2010;51:1015–25
    CrossRefPubMed
  27. 27.↵
    1. Kwee RM,
    2. Truijman MT,
    3. van Oostenbrugge RJ, et al
    . Longitudinal MRI study on the natural history of carotid artery plaques in symptomatic patients. PLoS One 2012;7:e42472
    CrossRefPubMed
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American Journal of Neuroradiology: 36 (2)
American Journal of Neuroradiology
Vol. 36, Issue 2
1 Feb 2015
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Cite this article
A. Gupta, E.E. Mtui, H. Baradaran, G. Salama, A. Pandya, H. Kamel, A. Giambrone, P.C. Sanelli
CT Angiographic Features of Symptom-Producing Plaque in Moderate-Grade Carotid Artery Stenosis
American Journal of Neuroradiology Feb 2015, 36 (2) 349-354; DOI: 10.3174/ajnr.A4098

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CT Angiographic Features of Symptom-Producing Plaque in Moderate-Grade Carotid Artery Stenosis
A. Gupta, E.E. Mtui, H. Baradaran, G. Salama, A. Pandya, H. Kamel, A. Giambrone, P.C. Sanelli
American Journal of Neuroradiology Feb 2015, 36 (2) 349-354; DOI: 10.3174/ajnr.A4098
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