Brain Region–Specific Degeneration with Disease Progression in Late Infantile Neuronal Ceroid Lipofuscinosis (CLN2 Disease)

J.P. Dyke; D. Sondhi; H.U. Voss; K. Yohay; C. Hollmann; D. Mancenido; S.M. Kaminsky; L.A. Heier; K.D. Rudser; B. Kosofsky; B.J. Casey; R.G. Crystal; D. Ballon

doi:10.3174/ajnr.A4669

Research ArticlePEDIATRICS

Open Access

Brain Region–Specific Degeneration with Disease Progression in Late Infantile Neuronal Ceroid Lipofuscinosis (CLN2 Disease)

J.P. Dyke, D. Sondhi, H.U. Voss, K. Yohay, C. Hollmann, D. Mancenido, S.M. Kaminsky, L.A. Heier, K.D. Rudser, B. Kosofsky, B.J. Casey, R.G. Crystal and D. Ballon

American Journal of Neuroradiology June 2016, 37 (6) 1160-1169; DOI: https://doi.org/10.3174/ajnr.A4669

J.P. Dyke

aFrom the Departments of Radiology (J.P.D., H.U.V., L.A.H., D.B.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for J.P. Dyke

D. Sondhi

bGenetic Medicine (D.S., C.H., D.M., S.M.K., R.G.C., D.B.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for D. Sondhi

H.U. Voss

aFrom the Departments of Radiology (J.P.D., H.U.V., L.A.H., D.B.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for H.U. Voss

K. Yohay

cPediatrics (K.Y., B.K.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for K. Yohay

C. Hollmann

bGenetic Medicine (D.S., C.H., D.M., S.M.K., R.G.C., D.B.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for C. Hollmann

D. Mancenido

bGenetic Medicine (D.S., C.H., D.M., S.M.K., R.G.C., D.B.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for D. Mancenido

S.M. Kaminsky

bGenetic Medicine (D.S., C.H., D.M., S.M.K., R.G.C., D.B.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for S.M. Kaminsky

L.A. Heier

aFrom the Departments of Radiology (J.P.D., H.U.V., L.A.H., D.B.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for L.A. Heier

K.D. Rudser

eDivision of Biostatistics (K.D.R.), Clinical and Translational Science Institute, University of Minnesota, Minneapolis, Minnesota.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for K.D. Rudser

B. Kosofsky

cPediatrics (K.Y., B.K.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for B. Kosofsky

B.J. Casey

dPsychiatry (B.J.C.), Weill Cornell Medical College, New York, New York

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for B.J. Casey

R.G. Crystal

bGenetic Medicine (D.S., C.H., D.M., S.M.K., R.G.C., D.B.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for R.G. Crystal

D. Ballon

aFrom the Departments of Radiology (J.P.D., H.U.V., L.A.H., D.B.)

bGenetic Medicine (D.S., C.H., D.M., S.M.K., R.G.C., D.B.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for D. Ballon

Article
Figures & Data
Supplemental
Info & Metrics
Responses
References
PDF

Data supplements

Files in this Data Supplement:

Supplemental Online Tables

PreviousNext

In this issue

American Journal of Neuroradiology

Vol. 37, Issue 6

1 Jun 2016

Table of Contents
Index by author
Complete Issue (PDF)

Download PDF

Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Brain Region–Specific Degeneration with Disease Progression in Late Infantile Neuronal Ceroid Lipofuscinosis (CLN2 Disease)

Message Subject (Your Name) has sent you a message from American Journal of Neuroradiology

Message Body (Your Name) thought you would like to see the American Journal of Neuroradiology web site.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Cite this article

J.P. Dyke, D. Sondhi, H.U. Voss, K. Yohay, C. Hollmann, D. Mancenido, S.M. Kaminsky, L.A. Heier, K.D. Rudser, B. Kosofsky, B.J. Casey, R.G. Crystal, D. Ballon

Brain Region–Specific Degeneration with Disease Progression in Late Infantile Neuronal Ceroid Lipofuscinosis (CLN2 Disease)

American Journal of Neuroradiology Jun 2016, 37 (6) 1160-1169; DOI: 10.3174/ajnr.A4669

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

0 Responses

Respond to this article

Bookmark this article

User Name *

Password *

Remember my user name & password.

Brain Region–Specific Degeneration with Disease Progression in Late Infantile Neuronal Ceroid Lipofuscinosis (CLN2 Disease)

J.P. Dyke, D. Sondhi, H.U. Voss, K. Yohay, C. Hollmann, D. Mancenido, S.M. Kaminsky, L.A. Heier, K.D. Rudser, B. Kosofsky, B.J. Casey, R.G. Crystal, D. Ballon

American Journal of Neuroradiology Jun 2016, 37 (6) 1160-1169; DOI: 10.3174/ajnr.A4669

Share This Article:

Tweet Widget
Facebook Like
Google Plus One

Purchase

Jump to section

Article
Figures & Data
Supplemental
Info & Metrics
Responses
References
PDF

PubMed
Google Scholar

Cited By...

Enzyme Replacement Therapy for CLN2 Disease: MRI Volumetry Shows Significantly Slower Volume Loss Compared with a Natural History Cohort
Slowing late infantile Batten disease by direct brain parenchymal administration of a rh.10 adeno-associated virus expressing CLN2
Expanding the Neuroimaging Phenotype of Neuronal Ceroid Lipofuscinoses

Crossref (21)
Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

Clinical challenges and future therapeutic approaches for neuronal ceroid lipofuscinosis

Sara E Mole, Glenn Anderson, Heather A Band, Samuel F Berkovic, Jonathan D Cooper, Sophia-Martha Kleine Holthaus, Tristan R McKay, Diego L Medina, Ahad A Rahim, Angela Schulz, Alexander J Smith

The Lancet Neurology 2019 18 1
Slowing late infantile Batten disease by direct brain parenchymal administration of a rh.10 adeno-associated virus expressing CLN2

Dolan Sondhi, Stephen M. Kaminsky, Neil R. Hackett, Odelya E. Pagovich, Jonathan B. Rosenberg, Bishnu P. De, Alvin Chen, Benjamin Van de Graaf, Jason G. Mezey, Grace W. Mammen, Denesy Mancenido, Fang Xu, Barry Kosofsky, Kaleb Yohay, Stefan Worgall, Robert J. Kaner, Mark Souwedaine, Bruce M. Greenwald, Michael Kaplitt, Jonathan P. Dyke, Douglas J. Ballon, Linda A. Heier, Szilard Kiss, Ronald G. Crystal

Science Translational Medicine 2020 12 572
Photosensitivity is an early marker of neuronal ceroid lipofuscinosis type 2 disease

Nicola Specchio, Marcello Bellusci, Nicola Pietrafusa, Marina Trivisano, Luca de Palma, Federico Vigevano

Epilepsia 2017 58 8
Neuronal Ceroid Lipofuscinosis: Potential for Targeted Therapy

Nicola Specchio, Alessandro Ferretti, Marina Trivisano, Nicola Pietrafusa, Chiara Pepi, Costanza Calabrese, Susanna Livadiotti, Alessandra Simonetti, Paolo Rossi, Paolo Curatolo, Federico Vigevano

Drugs 2021 81 1
Neuronal Ceroid Lipofuscinosis: The Multifaceted Approach to the Clinical Issues, an Overview

Alessandro Simonati, Ruth E. Williams

Frontiers in Neurology 2022 13
<p>Changing Times for CLN2 Disease: The Era of Enzyme Replacement Therapy</p>

Nicola Specchio, Nicola Pietrafusa, Marina Trivisano

Therapeutics and Clinical Risk Management 2020 Volume 16
Extracellular Vesicles as Drug Carriers for Enzyme Replacement Therapy to Treat CLN2 Batten Disease: Optimization of Drug Administration Routes

Matthew J. Haney, Yuling Zhao, Yeon S. Jin, Elena V. Batrakova

Cells 2020 9 5
Advances in the treatment of neuronal ceroid lipofuscinosis

Jonathan B. Rosenberg, Alvin Chen, Stephen M. Kaminsky, Ronald G. Crystal, Dolan Sondhi

Expert Opinion on Orphan Drugs 2019 7 11
Expanding the Neuroimaging Phenotype of Neuronal Ceroid Lipofuscinoses

A. Biswas, P. Krishnan, A. Amirabadi, S. Blaser, S. Mercimek-Andrews, M. Shroff

American Journal of Neuroradiology 2020 41 10
Computed tomography provides enhanced techniques for longitudinal monitoring of progressive intracranial volume loss associated with regional neurodegeneration in ovine neuronal ceroid lipofuscinoses

Katharina N. Russell, Nadia L. Mitchell, Nigel G. Anderson, Craig R. Bunt, Martin P. Wellby, Tracy R. Melzer, Graham K. Barrell, David N. Palmer

Brain and Behavior 2018 8 9

Main menu

User menu

Search

American Journal of Neuroradiology

Brain Region–Specific Degeneration with Disease Progression in Late Infantile Neuronal Ceroid Lipofuscinosis (CLN2 Disease)

Data supplements

In this issue

Citation Manager Formats

Related Articles

Cited By...

More in this TOC Section

Similar Articles

Indexed Content

Cases

Special Collections

More from AJNR

Multimedia

Resources

About Us

American Society of Neuroradiology