Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • ASNR Foundation Special Collection
    • Most Impactful AJNR Articles
    • Photon-Counting CT
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • ASNR Foundation Special Collection
    • Most Impactful AJNR Articles
    • Photon-Counting CT
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR is seeking candidates for the AJNR Podcast Editor. Read the position description.

Research ArticleAdult Brain
Open Access

Longitudinal Microstructural Changes in Traumatic Brain Injury in Rats: A Diffusional Kurtosis Imaging, Histology, and Behavior Study

M.-L. Wang, M.-M. Yu, D.-X. Yang, Y.-L. Liu, X.-E. Wei and W.-B. Li
American Journal of Neuroradiology September 2018, 39 (9) 1650-1656; DOI: https://doi.org/10.3174/ajnr.A5737
M.-L. Wang
aFrom the Departments of Radiology (M.-L.W., M.-M.Y., X.-E.W., W.-B.L.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for M.-L. Wang
M.-M. Yu
aFrom the Departments of Radiology (M.-L.W., M.-M.Y., X.-E.W., W.-B.L.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for M.-M. Yu
D.-X. Yang
bNeurosurgery (D.-X.Y., Y.-L.L.), Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for D.-X. Yang
Y.-L. Liu
bNeurosurgery (D.-X.Y., Y.-L.L.), Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Y.-L. Liu
X.-E. Wei
aFrom the Departments of Radiology (M.-L.W., M.-M.Y., X.-E.W., W.-B.L.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for X.-E. Wei
W.-B. Li
aFrom the Departments of Radiology (M.-L.W., M.-M.Y., X.-E.W., W.-B.L.)
cImaging Center (W.-B.L.), Kashgar Prefecture Second People's Hospital, Kashgar, China.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for W.-B. Li
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

Article Figures & Data

Figures

  • Fig 1.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 1.

    Illustration of ROIs on B0 (A–C) and histology (D–F) maps for a representative control and TBI rat. Regions shown are the bilateral cortex, bilateral hippocampus, and corpus callosum.

  • Fig 2.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 2.

    Changes in FA, MD, and MK values for the bilateral cortex (ips, con), bilateral hippocampus (ips, con), and corpus callosum and changes in Da, Dr, Ka, and Kr values for the corpus callosum. The asterisk indicates P < .05, compared with preinjury; hash tag, P < .05, compared with 3 days after TBI; caret, P < .05, compared with 14 days after TBI; ips, ipsilateral; con, contralateral.

  • Fig 3.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 3.

    Changes in NeuN+, GFAP+, and Iba-1+ cells and MBP area for the bilateral cortex (ips, con), bilateral hippocampus (ips, con), and corpus callosum. Asterisk indicates P < .05, compared with preinjury; hash tag, P < .05, compared with 3 days after TBI; caret, P < .05, compared with 14 days after TBI; ips, ipsilateral; con, contralateral.

  • Fig 4.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Fig 4.

    The Morris water maze tests results. A, Latency to find the platform. B, Platform-crossing times. C, Time spent in target quadrant. D, The swimming speed. Error bars indicate standard error. Asterisk indicates P < .05.

PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 39 (9)
American Journal of Neuroradiology
Vol. 39, Issue 9
1 Sep 2018
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Longitudinal Microstructural Changes in Traumatic Brain Injury in Rats: A Diffusional Kurtosis Imaging, Histology, and Behavior Study
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
M.-L. Wang, M.-M. Yu, D.-X. Yang, Y.-L. Liu, X.-E. Wei, W.-B. Li
Longitudinal Microstructural Changes in Traumatic Brain Injury in Rats: A Diffusional Kurtosis Imaging, Histology, and Behavior Study
American Journal of Neuroradiology Sep 2018, 39 (9) 1650-1656; DOI: 10.3174/ajnr.A5737

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Longitudinal Microstructural Changes in Traumatic Brain Injury in Rats: A Diffusional Kurtosis Imaging, Histology, and Behavior Study
M.-L. Wang, M.-M. Yu, D.-X. Yang, Y.-L. Liu, X.-E. Wei, W.-B. Li
American Journal of Neuroradiology Sep 2018, 39 (9) 1650-1656; DOI: 10.3174/ajnr.A5737
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Footnotes
    • References
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • PubMed
  • Google Scholar

Cited By...

  • A Pilot Study to Establish a Penetrating Traumatic Brain Injury Rat Model for Implantation of a 3D Printed Scaffold
  • LONGITUDINAL CHANGES IN WHITE MATTER MICROSTRUCTURAL STATUS FOLLOWING QUANTIFIED HEAD-BALL IMPACTS IN SOCCER: A PRELIMINARY, PROSPECTIVE STUDY
  • Neuroanatomical underpinning of diffusion kurtosis measurements in the cerebral cortex of healthy macaque brains
  • Longitudinal, Multiparametric MRI Assessment of repetitive mild TBI in rats
  • Behavioral and Structural Effects of Single and Repeat Closed-Head Injury
  • Crossref (17)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Rapid microstructural plasticity in the cortical semantic network following a short language learning session
    Nikola Vukovic, Brian Hansen, Torben Ellegaard Lund, Sune Jespersen, Yury Shtyrov, Timothy D. Griffiths
    PLOS Biology 2021 19 6
  • Damage Mechanisms to Oligodendrocytes and White Matter in Central Nervous System Injury: The Australian Context
    Andrew Warnock, Lillian M. Toomey, Alexander J. Wright, Katherine Fisher, Yerim Won, Chidozie Anyaegbu, Melinda Fitzgerald
    Journal of Neurotrauma 2020 37 5
  • Dynamics of blood brain barrier permeability and tissue microstructure following controlled cortical impact injury in rat: A dynamic contrast-enhanced magnetic resonance imaging and diffusion kurtosis imaging study
    Mengmeng Yu, Mingliang Wang, Dianxu Yang, Xiaoer Wei, Wenbin Li
    Magnetic Resonance Imaging 2019 62
  • Cortical Electrical Stimulation Ameliorates Traumatic Brain Injury-Induced Sensorimotor and Cognitive Deficits in Rats
    Chi-Wei Kuo, Ming-Yuan Chang, Hui-Hua Liu, Xiao-Kuo He, Shu-Yen Chan, Ying-Zu Huang, Chih-Wei Peng, Pi-Kai Chang, Chien-Yuan Pan, Tsung-Hsun Hsieh
    Frontiers in Neural Circuits 2021 15
  • Imaging Markers for the Characterization of Gray and White Matter Changes from Acute to Chronic Stages after Experimental Traumatic Brain Injury
    Michel R.T. Sinke, Willem M. Otte, Anu E. Meerwaldt, Bart A. A. Franx, Mohamed H. M. Ali, Fazle Rakib, Annette van der Toorn, Caroline L. van Heijningen, Christel Smeele, Tariq Ahmed, Erwin L.A. Blezer, Rick M. Dijkhuizen
    Journal of Neurotrauma 2021 38 12
  • Neuroanatomical underpinning of diffusion kurtosis measurements in the cerebral cortex of healthy macaque brains
    Tianjia Zhu, Qinmu Peng, Austin Ouyang, Hao Huang
    Magnetic Resonance in Medicine 2021 85 4
  • The effects of cytomegalovirus on brain structure following sport-related concussion
    Jonathan Savitz, Bryna D Goeckner, Bart N Ford, T Kent Teague, Haixia Zheng, Jaroslaw Harezlak, Rebekah Mannix, L Tugan Muftuler, Benjamin L Brett, Michael A McCrea, Timothy B Meier
    Brain 2023 146 10
  • Diffusion Tensor Imaging-Based Studies at the Group-Level Applied to Animal Models of Neurodegenerative Diseases
    Hans-Peter Müller, Francesco Roselli, Volker Rasche, Jan Kassubek
    Frontiers in Neuroscience 2020 14
  • Early stage of diffusional kurtosis imaging and dynamic contrast-enhanced magnetic resonance imaging correlated with long-term neurocognitive function after experimental traumatic brain injury
    Mengmeng Yu, Dianxu Yang, Mingliang Wang, Xiaoer Wei, Wenbin Li
    Neuroscience Letters 2019 705
  • Enhancing Metabolic Imaging of Energy Metabolism in Traumatic Brain Injury Using Hyperpolarized [1-13C]Pyruvate and Dichloroacetate
    Stephen J. DeVience, Xin Lu, Julie L. Proctor, Parisa Rangghran, Juliana A. Medina, Elias R. Melhem, Rao P. Gullapalli, Gary Fiskum, Dirk Mayer
    Metabolites 2021 11 6

More in this TOC Section

  • Diagnostic Neuroradiology of Monoclonal Antibodies
  • Clinical Outcomes After Chiari I Decompression
  • Segmentation of Brain Metastases with BLAST
Show more Adult Brain

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

Special Collections

  • AJNR Awards
  • ASNR Foundation Special Collection
  • Most Impactful AJNR Articles
  • Photon-Counting CT
  • Spinal CSF Leak Articles (Jan 2020-June 2024)

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire