Index by author
A
Aboab, J.
- FELLOWS' JOURNAL CLUBAdult BrainYou have accessDiagnosis and Prediction of Relapses in Susac Syndrome: A New Use for MR Postcontrast FLAIR Leptomeningeal EnhancementS. Coulette, A. Lecler, E. Saragoussi, K. Zuber, J. Savatovsky, R. Deschamps, O. Gout, C. Sabben, J. Aboab, A. Affortit, F. Charbonneau and M. ObadiaAmerican Journal of Neuroradiology July 2019, 40 (7) 1184-1190; DOI: https://doi.org/10.3174/ajnr.A6103
From January 2011 to December 2017, nine consecutive patients with Susac syndrome and a control group of 73 patients with multiple sclerosis or clinically isolated syndrome were included. Two neuroradiologists blinded to the clinical and ophthalmologic data independently reviewed MRIs and assessed leptomeningeal enhancement and parenchymal abnormalities. Follow-up MRIs of patients with Susac syndrome were reviewed and compared with clinical and retinal fluorescein angiographic data evaluated by an independent ophthalmologist. Patients with Susac syndrome were significantly more likely to present with leptomeningeal enhancement: 5/9 (56%) versus 6/73 (8%) in the control group. They had a significantly higher leptomeningeal enhancement burden with ≥3 lesions in 5/9 patients versus 0/73. Regions of leptomeningeal enhancement were significantly more likely to be located in the posterior fossa. The authors conclude that leptomeningeal enhancement occurs frequently in Susac syndrome and could be helpful for diagnosis and prediction of clinical relapse.
Adams, M.
- SpineYou have accessQuantification of DTI in the Pediatric Spinal Cord: Application to Clinical Evaluation in a Healthy Patient PopulationB.B. Reynolds, S. By, Q.R. Weinberg, A.A. Witt, A.T. Newton, H.R. Feiler, B. Ramkorun, D.B. Clayton, P. Couture, J.E. Martus, M. Adams, J.C. Wellons, S.A. Smith and A. BhatiaAmerican Journal of Neuroradiology July 2019, 40 (7) 1236-1241; DOI: https://doi.org/10.3174/ajnr.A6104
Affortit, A.
- FELLOWS' JOURNAL CLUBAdult BrainYou have accessDiagnosis and Prediction of Relapses in Susac Syndrome: A New Use for MR Postcontrast FLAIR Leptomeningeal EnhancementS. Coulette, A. Lecler, E. Saragoussi, K. Zuber, J. Savatovsky, R. Deschamps, O. Gout, C. Sabben, J. Aboab, A. Affortit, F. Charbonneau and M. ObadiaAmerican Journal of Neuroradiology July 2019, 40 (7) 1184-1190; DOI: https://doi.org/10.3174/ajnr.A6103
From January 2011 to December 2017, nine consecutive patients with Susac syndrome and a control group of 73 patients with multiple sclerosis or clinically isolated syndrome were included. Two neuroradiologists blinded to the clinical and ophthalmologic data independently reviewed MRIs and assessed leptomeningeal enhancement and parenchymal abnormalities. Follow-up MRIs of patients with Susac syndrome were reviewed and compared with clinical and retinal fluorescein angiographic data evaluated by an independent ophthalmologist. Patients with Susac syndrome were significantly more likely to present with leptomeningeal enhancement: 5/9 (56%) versus 6/73 (8%) in the control group. They had a significantly higher leptomeningeal enhancement burden with ≥3 lesions in 5/9 patients versus 0/73. Regions of leptomeningeal enhancement were significantly more likely to be located in the posterior fossa. The authors conclude that leptomeningeal enhancement occurs frequently in Susac syndrome and could be helpful for diagnosis and prediction of clinical relapse.
Algra, A.
- Adult BrainYou have accessGadolinium Enhancement of the Aneurysm Wall in Unruptured Intracranial Aneurysms Is Associated with an Increased Risk of Aneurysm Instability: A Follow-Up StudyM.D.I. Vergouwen, D. Backes, I.C. van der Schaaf, J. Hendrikse, R. Kleinloog, A. Algra and G.J.E. RinkelAmerican Journal of Neuroradiology July 2019, 40 (7) 1112-1116; DOI: https://doi.org/10.3174/ajnr.A6105
Alhilali, L.M.
- Adult BrainOpen AccessAssessing Postconcussive Reaction Time Using Transport-Based Morphometry of Diffusion Tensor ImagesS. Kundu, A. Ghodadra, S. Fakhran, L.M. Alhilali and G.K. RohdeAmerican Journal of Neuroradiology July 2019, 40 (7) 1117-1123; DOI: https://doi.org/10.3174/ajnr.A6087
Amirabadi, A.
- EDITOR'S CHOICEPediatricsYou have accessPredictive Value of MRI in Diagnosing Brain AVM Recurrence after Angiographically Documented Exclusion in ChildrenA. Jhaveri, A. Amirabadi, P. Dirks, A.V. Kulkarni, M.M. Shroff, N. Shkumat, T. Krings, V.M. Pereira, V. Rea and P. MuthusamiAmerican Journal of Neuroradiology July 2019, 40 (7) 1227-1235; DOI: https://doi.org/10.3174/ajnr.A6093
The authors sought to determine the predictive values of contrast-enhanced MR imaging and TOF-MRA for brain AVM recurrence in children, compared with conventional angiography, in 39 patients (mean 10.8 years of age, mean Spetzler-Martin grade, 1.9). Features predictive of recurrence included a tuft of vessels on TOF-MRA and nodular juxtamural/linear enhancement with a draining vein on contrast-enhanced MR imaging. MR imaging is useful for surveillance after brain AVM treatment in children, but conventional angiography is required for definitive diagnosis of recurrence. TOF-MRA and contrast-enhanced MR imaging provide complementary information for determining brain AVM recurrence and should be interpreted in conjunction.
Arnold, D.L.
- EDITOR'S CHOICEAdult BrainOpen AccessComparison of Multiple Sclerosis Cortical Lesion Types Detected by Multicontrast 3T and 7T MRIJ. Maranzano, M. Dadar, D.A. Rudko, D. De Nigris, C. Elliott, J.S. Gati, S.A. Morrow, R.S. Menon, D.L. Collins, D.L. Arnold and S. NarayananAmerican Journal of Neuroradiology July 2019, 40 (7) 1162-1169; DOI: https://doi.org/10.3174/ajnr.A6099
The aim of the authors was: 1) to compare multicontrast cortical lesion detection using 3T and 7T MR imaging, 2) to compare cortical lesion type frequency in relapsing-remitting and secondary-progressive MS, and 3) to assess whether detectability is related to the magnetization transfer ratio, an imaging marker sensitive to myelin content. Multicontrast 3T and 7T MR images from 10 patients with relapsing-remitting MS and 10 with secondary-progressive MS were evaluated with the following 3T contrasts: 3D-T1-weighted, quantitative T1, FLAIR and magnetization-transfer, and 2D proton density- and T2-weighted. The following 7T contrasts were used: 3D-T1-weighted, quantitative T1, and 2D-T2*-weighted. Cortical lesion counts at 7T were the following: 720 total cortical lesions, 420 leukocortical lesions (58%), 27 intracortical lesions (4%), and 273 subpial lesions (38%). Cortical lesion counts at 3T were the following: 424 total cortical, 393 leukocortical (93%), 0intracortical, and 31 subpial (7%) lesions. Total, intracortical, and subpial 3T lesion counts were significantly lower than the 7Tcounts. The authors conclude that detection of leukocortical lesions at 3T is comparable with that at 7T MR imaging. Imaging at 3T is less sensitive to intracortical and subpial lesions.
Asai, K.
- FELLOWS' JOURNAL CLUBInterventionalYou have accessLong-Term Results and Follow-Up Examinations after Endovascular Embolization for Unruptured Cerebral AneurysmsT. Murakami, T. Nishida, K. Asai, Y. Kadono, H. Nakamura, T. Fujinaka and H. KishimaAmerican Journal of Neuroradiology July 2019, 40 (7) 1191-1196; DOI: https://doi.org/10.3174/ajnr.A6101
The appropriate period of follow-up examinations after endovascular embolization for cerebral aneurysms using time-of-flight MR angiography is not well-known. Between April 2006 and March 2011, one hundred forty-eight unruptured aneurysms were treated with endovascular coil embolization. Among them, the authors investigated 116 unruptured aneurysms, which were followed up for >5 years. Time-of-flight MRA was performed at 1 day, 3–6 months, 1 year after the procedure, and every year thereafter. The mean follow-up period was 7.0 years. Recanalization was observed in 19 (16.3%) aneurysms within 2 years. Among them, retreatment was performed in 8 (6.8%) aneurysms. No recanalization was detected in any aneurysms that had been stable in the first 2 years after embolization. They conclude that aneurysms in which recanalization was not observed within 2 years after endovascular coil embolization were stable during a mean follow-up of 7 years. This result may be helpful in considering the appropriate span or frequency of follow-up imaging for embolized cerebral aneurysms.
B
Backes, D.
- Adult BrainYou have accessGadolinium Enhancement of the Aneurysm Wall in Unruptured Intracranial Aneurysms Is Associated with an Increased Risk of Aneurysm Instability: A Follow-Up StudyM.D.I. Vergouwen, D. Backes, I.C. van der Schaaf, J. Hendrikse, R. Kleinloog, A. Algra and G.J.E. RinkelAmerican Journal of Neuroradiology July 2019, 40 (7) 1112-1116; DOI: https://doi.org/10.3174/ajnr.A6105
Bansal, A.G.
- Adult BrainYou have accessExtent of Surgical Resection in Lower-Grade Gliomas: Differential Impact Based on Molecular SubtypeS.H. Patel, A.G. Bansal, E.B. Young, P.P. Batchala, J.T. Patrie, M.B. Lopes, R. Jain, C.E. Fadul and D. SchiffAmerican Journal of Neuroradiology July 2019, 40 (7) 1149-1155; DOI: https://doi.org/10.3174/ajnr.A6102
Barboriak, D.P.
- Adult BrainOpen AccessQuantitative Delta T1 (dT1) as a Replacement for Adjudicated Central Reader Analysis of Contrast-Enhancing Tumor Burden: A Subanalysis of the American College of Radiology Imaging Network 6677/Radiation Therapy Oncology Group 0625 Multicenter Brain Tumor TrialK.M. Schmainda, M.A. Prah, Z. Zhang, B.S. Snyder, S.D. Rand, T.R. Jensen, D.P. Barboriak and J.L. BoxermanAmerican Journal of Neuroradiology July 2019, 40 (7) 1132-1139; DOI: https://doi.org/10.3174/ajnr.A6110
Batchala, P.P.
- Adult BrainYou have accessExtent of Surgical Resection in Lower-Grade Gliomas: Differential Impact Based on Molecular SubtypeS.H. Patel, A.G. Bansal, E.B. Young, P.P. Batchala, J.T. Patrie, M.B. Lopes, R. Jain, C.E. Fadul and D. SchiffAmerican Journal of Neuroradiology July 2019, 40 (7) 1149-1155; DOI: https://doi.org/10.3174/ajnr.A6102
Bednarek, D.R.
- InterventionalYou have accessFlow-Pattern Details in an Aneurysm Model Using High-Speed 1000-Frames-per-Second AngiographyJ.M. Krebs, A. Shankar, S.V. Setlur Nagesh, J.M. Davies, K.V. Snyder, E.I. Levy, L.N. Hopkins, M. Mokin, D.R. Bednarek, A.H. Siddiqui and S. RudinAmerican Journal of Neuroradiology July 2019, 40 (7) 1197-1200; DOI: https://doi.org/10.3174/ajnr.A6090
Bhatia, A.
- SpineYou have accessQuantification of DTI in the Pediatric Spinal Cord: Application to Clinical Evaluation in a Healthy Patient PopulationB.B. Reynolds, S. By, Q.R. Weinberg, A.A. Witt, A.T. Newton, H.R. Feiler, B. Ramkorun, D.B. Clayton, P. Couture, J.E. Martus, M. Adams, J.C. Wellons, S.A. Smith and A. BhatiaAmerican Journal of Neuroradiology July 2019, 40 (7) 1236-1241; DOI: https://doi.org/10.3174/ajnr.A6104
Bonafe, A.
- InterventionalYou have accessAntiplatelet Therapy in Patients with Aneurysmal SAH: Impact on Delayed Cerebral Ischemia and Clinical Outcome. A Meta-AnalysisF. Cagnazzo, I. Derraz, P.-H. Lefevre, G. Gascou, C. Dargazanli, C. Riquelme, P. Perrini, D. di Carlo, A. Bonafe and V. CostalatAmerican Journal of Neuroradiology July 2019, 40 (7) 1201-1206; DOI: https://doi.org/10.3174/ajnr.A6086
Boni, R.C.
- Adult BrainYou have accessImpact of Skull Defects on the Role of CTA for Brain Death ConfirmationD.M. Nunes, A.C.M. Maia, R.C. Boni and A.J. da RochaAmerican Journal of Neuroradiology July 2019, 40 (7) 1177-1183; DOI: https://doi.org/10.3174/ajnr.A6100
Boxerman, J.L.
- Adult BrainOpen AccessQuantitative Delta T1 (dT1) as a Replacement for Adjudicated Central Reader Analysis of Contrast-Enhancing Tumor Burden: A Subanalysis of the American College of Radiology Imaging Network 6677/Radiation Therapy Oncology Group 0625 Multicenter Brain Tumor TrialK.M. Schmainda, M.A. Prah, Z. Zhang, B.S. Snyder, S.D. Rand, T.R. Jensen, D.P. Barboriak and J.L. BoxermanAmerican Journal of Neuroradiology July 2019, 40 (7) 1132-1139; DOI: https://doi.org/10.3174/ajnr.A6110
Braileanu, M.
- You have accessAssessment of Explicitly Stated Interval Change on Noncontrast Head CT Radiology ReportsM. Braileanu, K. Crawford, S.R. Key and M.E. MullinsAmerican Journal of Neuroradiology July 2019, 40 (7) 1091-1094; DOI: https://doi.org/10.3174/ajnr.A6081
Bruno, M.T.
- FELLOWS' JOURNAL CLUBAdult BrainOpen Access3T MRI Whole-Brain Microscopy Discrimination of Subcortical Anatomy, Part 2: Basal ForebrainM.J. Hoch, M.T. Bruno, A. Faustin, N. Cruz, A.Y. Mogilner, L. Crandall, T. Wisniewski, O. Devinsky and T.M. ShepherdAmerican Journal of Neuroradiology July 2019, 40 (7) 1095-1105; DOI: https://doi.org/10.3174/ajnr.A6088
The authors applied an optimized TSE T2 sequence to washed whole postmortem brain samples (n=13) to demonstrate and characterize the detailed anatomy of the basal forebrain using a clinical 3T MR imaging scanner. Theyidentified most basal ganglia and diencephalon structures using serial axial, coronal, and sagittal planes relative to the intercommissural plane. Specific oblique image orientations demonstrated the positions and anatomic relationships for selected structures of interest to functional neurosurgery.
By, S.
- SpineYou have accessQuantification of DTI in the Pediatric Spinal Cord: Application to Clinical Evaluation in a Healthy Patient PopulationB.B. Reynolds, S. By, Q.R. Weinberg, A.A. Witt, A.T. Newton, H.R. Feiler, B. Ramkorun, D.B. Clayton, P. Couture, J.E. Martus, M. Adams, J.C. Wellons, S.A. Smith and A. BhatiaAmerican Journal of Neuroradiology July 2019, 40 (7) 1236-1241; DOI: https://doi.org/10.3174/ajnr.A6104
C
Cagnazzo, F.
- InterventionalYou have accessAntiplatelet Therapy in Patients with Aneurysmal SAH: Impact on Delayed Cerebral Ischemia and Clinical Outcome. A Meta-AnalysisF. Cagnazzo, I. Derraz, P.-H. Lefevre, G. Gascou, C. Dargazanli, C. Riquelme, P. Perrini, D. di Carlo, A. Bonafe and V. CostalatAmerican Journal of Neuroradiology July 2019, 40 (7) 1201-1206; DOI: https://doi.org/10.3174/ajnr.A6086
Cankurtaran, C.Z.
- FunctionalOpen AccessA Practical Review of Functional MRI Anatomy of the Language and Motor SystemsV.B. Hill, C.Z. Cankurtaran, B.P. Liu, T.A. Hijaz, M. Naidich, A.J. Nemeth, J. Gastala, C. Krumpelman, E.N. McComb and A.W. KorutzAmerican Journal of Neuroradiology July 2019, 40 (7) 1084-1090; DOI: https://doi.org/10.3174/ajnr.A6089
Charbonneau, F.
- FELLOWS' JOURNAL CLUBAdult BrainYou have accessDiagnosis and Prediction of Relapses in Susac Syndrome: A New Use for MR Postcontrast FLAIR Leptomeningeal EnhancementS. Coulette, A. Lecler, E. Saragoussi, K. Zuber, J. Savatovsky, R. Deschamps, O. Gout, C. Sabben, J. Aboab, A. Affortit, F. Charbonneau and M. ObadiaAmerican Journal of Neuroradiology July 2019, 40 (7) 1184-1190; DOI: https://doi.org/10.3174/ajnr.A6103
From January 2011 to December 2017, nine consecutive patients with Susac syndrome and a control group of 73 patients with multiple sclerosis or clinically isolated syndrome were included. Two neuroradiologists blinded to the clinical and ophthalmologic data independently reviewed MRIs and assessed leptomeningeal enhancement and parenchymal abnormalities. Follow-up MRIs of patients with Susac syndrome were reviewed and compared with clinical and retinal fluorescein angiographic data evaluated by an independent ophthalmologist. Patients with Susac syndrome were significantly more likely to present with leptomeningeal enhancement: 5/9 (56%) versus 6/73 (8%) in the control group. They had a significantly higher leptomeningeal enhancement burden with ≥3 lesions in 5/9 patients versus 0/73. Regions of leptomeningeal enhancement were significantly more likely to be located in the posterior fossa. The authors conclude that leptomeningeal enhancement occurs frequently in Susac syndrome and could be helpful for diagnosis and prediction of clinical relapse.
Chen, B.
- Adult BrainYou have accessWall Contrast Enhancement of Thrombosed Intracranial Aneurysms at 7T MRIT. Sato, T. Matsushige, B. Chen, O. Gembruch, P. Dammann, R. Jabbarli, M. Forsting, A. Junker, S. Maderwald, H.H. Quick, M.E. Ladd, U. Sure and K.H. WredeAmerican Journal of Neuroradiology July 2019, 40 (7) 1106-1111; DOI: https://doi.org/10.3174/ajnr.A6084
Chopra, A.M.
- LETTERYou have accessPolymer Embolism from Bioactive and Hydrogel Coil Embolization Technology: Considerations for Product DevelopmentA.M. Chopra, J.P. Cruz and Y.C. HuAmerican Journal of Neuroradiology July 2019, 40 (7) E34-E35; DOI: https://doi.org/10.3174/ajnr.A6083
Cianfoni, A.
- EDITOR'S CHOICEAdult BrainYou have accessBrain Tumor-Enhancement Visualization and Morphometric Assessment: A Comparison of MPRAGE, SPACE, and VIBE MRI TechniquesL. Danieli, G.C. Riccitelli, D. Distefano, E. Prodi, E. Ventura, A. Cianfoni, A. Kaelin-Lang, M. Reinert and E. PravatàAmerican Journal of Neuroradiology July 2019, 40 (7) 1140-1148; DOI: https://doi.org/10.3174/ajnr.A6096
Fifty-four contrast-enhancing tumors (38 gliomas and 16 metastases) were assessed using MPRAGE, VIBE, and SPACE techniques randomly acquired after gadolinium-based contrast agent administration on a 3T scanner. Enhancement conspicuity was assessed quantitatively by calculating the contrast rate and contrast-to-noise ratio, and qualitatively, by consensus visual comparative ratings. Compared with MPRAGE, both SPACE and VIBE obtained higher contrast rate, contrast-to-noise ratio, and visual conspicuity ratings in both gliomas and metastases. The authors conclude that superior conspicuity for brain tumor enhancement can be achieved using SPACE and VIBE techniques, compared with MPRAGE.
Clayton, D.B.
- SpineYou have accessQuantification of DTI in the Pediatric Spinal Cord: Application to Clinical Evaluation in a Healthy Patient PopulationB.B. Reynolds, S. By, Q.R. Weinberg, A.A. Witt, A.T. Newton, H.R. Feiler, B. Ramkorun, D.B. Clayton, P. Couture, J.E. Martus, M. Adams, J.C. Wellons, S.A. Smith and A. BhatiaAmerican Journal of Neuroradiology July 2019, 40 (7) 1236-1241; DOI: https://doi.org/10.3174/ajnr.A6104
Coenen, W.
- SpineYou have accessSubject-Specific Studies of CSF Bulk Flow Patterns in the Spinal Canal: Implications for the Dispersion of Solute Particles in Intrathecal Drug DeliveryW. Coenen, C. Gutiérrez-Montes, S. Sincomb, E. Criado-Hidalgo, K. Wei, K. King, V. Haughton, C. Martínez-Bazán, A.L. Sánchez and J. C. LasherasAmerican Journal of Neuroradiology July 2019, 40 (7) 1242-1249; DOI: https://doi.org/10.3174/ajnr.A6097
Collins, D.L.
- EDITOR'S CHOICEAdult BrainOpen AccessComparison of Multiple Sclerosis Cortical Lesion Types Detected by Multicontrast 3T and 7T MRIJ. Maranzano, M. Dadar, D.A. Rudko, D. De Nigris, C. Elliott, J.S. Gati, S.A. Morrow, R.S. Menon, D.L. Collins, D.L. Arnold and S. NarayananAmerican Journal of Neuroradiology July 2019, 40 (7) 1162-1169; DOI: https://doi.org/10.3174/ajnr.A6099
The aim of the authors was: 1) to compare multicontrast cortical lesion detection using 3T and 7T MR imaging, 2) to compare cortical lesion type frequency in relapsing-remitting and secondary-progressive MS, and 3) to assess whether detectability is related to the magnetization transfer ratio, an imaging marker sensitive to myelin content. Multicontrast 3T and 7T MR images from 10 patients with relapsing-remitting MS and 10 with secondary-progressive MS were evaluated with the following 3T contrasts: 3D-T1-weighted, quantitative T1, FLAIR and magnetization-transfer, and 2D proton density- and T2-weighted. The following 7T contrasts were used: 3D-T1-weighted, quantitative T1, and 2D-T2*-weighted. Cortical lesion counts at 7T were the following: 720 total cortical lesions, 420 leukocortical lesions (58%), 27 intracortical lesions (4%), and 273 subpial lesions (38%). Cortical lesion counts at 3T were the following: 424 total cortical, 393 leukocortical (93%), 0intracortical, and 31 subpial (7%) lesions. Total, intracortical, and subpial 3T lesion counts were significantly lower than the 7Tcounts. The authors conclude that detection of leukocortical lesions at 3T is comparable with that at 7T MR imaging. Imaging at 3T is less sensitive to intracortical and subpial lesions.
Costalat, V.
- InterventionalYou have accessAntiplatelet Therapy in Patients with Aneurysmal SAH: Impact on Delayed Cerebral Ischemia and Clinical Outcome. A Meta-AnalysisF. Cagnazzo, I. Derraz, P.-H. Lefevre, G. Gascou, C. Dargazanli, C. Riquelme, P. Perrini, D. di Carlo, A. Bonafe and V. CostalatAmerican Journal of Neuroradiology July 2019, 40 (7) 1201-1206; DOI: https://doi.org/10.3174/ajnr.A6086
Coulette, S.
- FELLOWS' JOURNAL CLUBAdult BrainYou have accessDiagnosis and Prediction of Relapses in Susac Syndrome: A New Use for MR Postcontrast FLAIR Leptomeningeal EnhancementS. Coulette, A. Lecler, E. Saragoussi, K. Zuber, J. Savatovsky, R. Deschamps, O. Gout, C. Sabben, J. Aboab, A. Affortit, F. Charbonneau and M. ObadiaAmerican Journal of Neuroradiology July 2019, 40 (7) 1184-1190; DOI: https://doi.org/10.3174/ajnr.A6103
From January 2011 to December 2017, nine consecutive patients with Susac syndrome and a control group of 73 patients with multiple sclerosis or clinically isolated syndrome were included. Two neuroradiologists blinded to the clinical and ophthalmologic data independently reviewed MRIs and assessed leptomeningeal enhancement and parenchymal abnormalities. Follow-up MRIs of patients with Susac syndrome were reviewed and compared with clinical and retinal fluorescein angiographic data evaluated by an independent ophthalmologist. Patients with Susac syndrome were significantly more likely to present with leptomeningeal enhancement: 5/9 (56%) versus 6/73 (8%) in the control group. They had a significantly higher leptomeningeal enhancement burden with ≥3 lesions in 5/9 patients versus 0/73. Regions of leptomeningeal enhancement were significantly more likely to be located in the posterior fossa. The authors conclude that leptomeningeal enhancement occurs frequently in Susac syndrome and could be helpful for diagnosis and prediction of clinical relapse.
Couture, P.
- SpineYou have accessQuantification of DTI in the Pediatric Spinal Cord: Application to Clinical Evaluation in a Healthy Patient PopulationB.B. Reynolds, S. By, Q.R. Weinberg, A.A. Witt, A.T. Newton, H.R. Feiler, B. Ramkorun, D.B. Clayton, P. Couture, J.E. Martus, M. Adams, J.C. Wellons, S.A. Smith and A. BhatiaAmerican Journal of Neuroradiology July 2019, 40 (7) 1236-1241; DOI: https://doi.org/10.3174/ajnr.A6104
Crandall, L.
- FELLOWS' JOURNAL CLUBAdult BrainOpen Access3T MRI Whole-Brain Microscopy Discrimination of Subcortical Anatomy, Part 2: Basal ForebrainM.J. Hoch, M.T. Bruno, A. Faustin, N. Cruz, A.Y. Mogilner, L. Crandall, T. Wisniewski, O. Devinsky and T.M. ShepherdAmerican Journal of Neuroradiology July 2019, 40 (7) 1095-1105; DOI: https://doi.org/10.3174/ajnr.A6088
The authors applied an optimized TSE T2 sequence to washed whole postmortem brain samples (n=13) to demonstrate and characterize the detailed anatomy of the basal forebrain using a clinical 3T MR imaging scanner. Theyidentified most basal ganglia and diencephalon structures using serial axial, coronal, and sagittal planes relative to the intercommissural plane. Specific oblique image orientations demonstrated the positions and anatomic relationships for selected structures of interest to functional neurosurgery.
Crawford, K.
- You have accessAssessment of Explicitly Stated Interval Change on Noncontrast Head CT Radiology ReportsM. Braileanu, K. Crawford, S.R. Key and M.E. MullinsAmerican Journal of Neuroradiology July 2019, 40 (7) 1091-1094; DOI: https://doi.org/10.3174/ajnr.A6081
Criado-Hidalgo, E.
- SpineYou have accessSubject-Specific Studies of CSF Bulk Flow Patterns in the Spinal Canal: Implications for the Dispersion of Solute Particles in Intrathecal Drug DeliveryW. Coenen, C. Gutiérrez-Montes, S. Sincomb, E. Criado-Hidalgo, K. Wei, K. King, V. Haughton, C. Martínez-Bazán, A.L. Sánchez and J. C. LasherasAmerican Journal of Neuroradiology July 2019, 40 (7) 1242-1249; DOI: https://doi.org/10.3174/ajnr.A6097
Cruz, J.P.
- LETTERYou have accessPolymer Embolism from Bioactive and Hydrogel Coil Embolization Technology: Considerations for Product DevelopmentA.M. Chopra, J.P. Cruz and Y.C. HuAmerican Journal of Neuroradiology July 2019, 40 (7) E34-E35; DOI: https://doi.org/10.3174/ajnr.A6083
Cruz, N.
- FELLOWS' JOURNAL CLUBAdult BrainOpen Access3T MRI Whole-Brain Microscopy Discrimination of Subcortical Anatomy, Part 2: Basal ForebrainM.J. Hoch, M.T. Bruno, A. Faustin, N. Cruz, A.Y. Mogilner, L. Crandall, T. Wisniewski, O. Devinsky and T.M. ShepherdAmerican Journal of Neuroradiology July 2019, 40 (7) 1095-1105; DOI: https://doi.org/10.3174/ajnr.A6088
The authors applied an optimized TSE T2 sequence to washed whole postmortem brain samples (n=13) to demonstrate and characterize the detailed anatomy of the basal forebrain using a clinical 3T MR imaging scanner. Theyidentified most basal ganglia and diencephalon structures using serial axial, coronal, and sagittal planes relative to the intercommissural plane. Specific oblique image orientations demonstrated the positions and anatomic relationships for selected structures of interest to functional neurosurgery.
D
Dadar, M.
- EDITOR'S CHOICEAdult BrainOpen AccessComparison of Multiple Sclerosis Cortical Lesion Types Detected by Multicontrast 3T and 7T MRIJ. Maranzano, M. Dadar, D.A. Rudko, D. De Nigris, C. Elliott, J.S. Gati, S.A. Morrow, R.S. Menon, D.L. Collins, D.L. Arnold and S. NarayananAmerican Journal of Neuroradiology July 2019, 40 (7) 1162-1169; DOI: https://doi.org/10.3174/ajnr.A6099
The aim of the authors was: 1) to compare multicontrast cortical lesion detection using 3T and 7T MR imaging, 2) to compare cortical lesion type frequency in relapsing-remitting and secondary-progressive MS, and 3) to assess whether detectability is related to the magnetization transfer ratio, an imaging marker sensitive to myelin content. Multicontrast 3T and 7T MR images from 10 patients with relapsing-remitting MS and 10 with secondary-progressive MS were evaluated with the following 3T contrasts: 3D-T1-weighted, quantitative T1, FLAIR and magnetization-transfer, and 2D proton density- and T2-weighted. The following 7T contrasts were used: 3D-T1-weighted, quantitative T1, and 2D-T2*-weighted. Cortical lesion counts at 7T were the following: 720 total cortical lesions, 420 leukocortical lesions (58%), 27 intracortical lesions (4%), and 273 subpial lesions (38%). Cortical lesion counts at 3T were the following: 424 total cortical, 393 leukocortical (93%), 0intracortical, and 31 subpial (7%) lesions. Total, intracortical, and subpial 3T lesion counts were significantly lower than the 7Tcounts. The authors conclude that detection of leukocortical lesions at 3T is comparable with that at 7T MR imaging. Imaging at 3T is less sensitive to intracortical and subpial lesions.
Damania, D.
- Extracranial VascularYou have accessComparison of Carotid Endarterectomy and Stenting for Symptomatic Internal Carotid Artery Near-OcclusionJ. Kim, S. Male, D. Damania, B.S. Jahromi and R.P. TummalaAmerican Journal of Neuroradiology July 2019, 40 (7) 1207-1212; DOI: https://doi.org/10.3174/ajnr.A6085
Dammann, P.
- Adult BrainYou have accessWall Contrast Enhancement of Thrombosed Intracranial Aneurysms at 7T MRIT. Sato, T. Matsushige, B. Chen, O. Gembruch, P. Dammann, R. Jabbarli, M. Forsting, A. Junker, S. Maderwald, H.H. Quick, M.E. Ladd, U. Sure and K.H. WredeAmerican Journal of Neuroradiology July 2019, 40 (7) 1106-1111; DOI: https://doi.org/10.3174/ajnr.A6084
Damodaran, N.
- LETTERYou have accessAutomated Segmentation of Hippocampal Volume: The Next Step in Neuroradiologic Diagnosis of Mesial Temporal SclerosisN. DamodaranAmerican Journal of Neuroradiology July 2019, 40 (7) E38; DOI: https://doi.org/10.3174/ajnr.A6092
Danieli, L.
- EDITOR'S CHOICEAdult BrainYou have accessBrain Tumor-Enhancement Visualization and Morphometric Assessment: A Comparison of MPRAGE, SPACE, and VIBE MRI TechniquesL. Danieli, G.C. Riccitelli, D. Distefano, E. Prodi, E. Ventura, A. Cianfoni, A. Kaelin-Lang, M. Reinert and E. PravatàAmerican Journal of Neuroradiology July 2019, 40 (7) 1140-1148; DOI: https://doi.org/10.3174/ajnr.A6096
Fifty-four contrast-enhancing tumors (38 gliomas and 16 metastases) were assessed using MPRAGE, VIBE, and SPACE techniques randomly acquired after gadolinium-based contrast agent administration on a 3T scanner. Enhancement conspicuity was assessed quantitatively by calculating the contrast rate and contrast-to-noise ratio, and qualitatively, by consensus visual comparative ratings. Compared with MPRAGE, both SPACE and VIBE obtained higher contrast rate, contrast-to-noise ratio, and visual conspicuity ratings in both gliomas and metastases. The authors conclude that superior conspicuity for brain tumor enhancement can be achieved using SPACE and VIBE techniques, compared with MPRAGE.
Dargazanli, C.
- InterventionalYou have accessAntiplatelet Therapy in Patients with Aneurysmal SAH: Impact on Delayed Cerebral Ischemia and Clinical Outcome. A Meta-AnalysisF. Cagnazzo, I. Derraz, P.-H. Lefevre, G. Gascou, C. Dargazanli, C. Riquelme, P. Perrini, D. di Carlo, A. Bonafe and V. CostalatAmerican Journal of Neuroradiology July 2019, 40 (7) 1201-1206; DOI: https://doi.org/10.3174/ajnr.A6086
da Rocha, A.J.
- Adult BrainYou have accessImpact of Skull Defects on the Role of CTA for Brain Death ConfirmationD.M. Nunes, A.C.M. Maia, R.C. Boni and A.J. da RochaAmerican Journal of Neuroradiology July 2019, 40 (7) 1177-1183; DOI: https://doi.org/10.3174/ajnr.A6100
Davies, J.M.
- InterventionalYou have accessFlow-Pattern Details in an Aneurysm Model Using High-Speed 1000-Frames-per-Second AngiographyJ.M. Krebs, A. Shankar, S.V. Setlur Nagesh, J.M. Davies, K.V. Snyder, E.I. Levy, L.N. Hopkins, M. Mokin, D.R. Bednarek, A.H. Siddiqui and S. RudinAmerican Journal of Neuroradiology July 2019, 40 (7) 1197-1200; DOI: https://doi.org/10.3174/ajnr.A6090
De Bernardo, M.
- LETTERYou have accessOptic Nerve Evaluation in Idiopathic Intracranial HypertensionM. De Bernardo, L. Vitiello and N. RosaAmerican Journal of Neuroradiology July 2019, 40 (7) E36; DOI: https://doi.org/10.3174/ajnr.A6091
De Nigris, D.
- EDITOR'S CHOICEAdult BrainOpen AccessComparison of Multiple Sclerosis Cortical Lesion Types Detected by Multicontrast 3T and 7T MRIJ. Maranzano, M. Dadar, D.A. Rudko, D. De Nigris, C. Elliott, J.S. Gati, S.A. Morrow, R.S. Menon, D.L. Collins, D.L. Arnold and S. NarayananAmerican Journal of Neuroradiology July 2019, 40 (7) 1162-1169; DOI: https://doi.org/10.3174/ajnr.A6099
The aim of the authors was: 1) to compare multicontrast cortical lesion detection using 3T and 7T MR imaging, 2) to compare cortical lesion type frequency in relapsing-remitting and secondary-progressive MS, and 3) to assess whether detectability is related to the magnetization transfer ratio, an imaging marker sensitive to myelin content. Multicontrast 3T and 7T MR images from 10 patients with relapsing-remitting MS and 10 with secondary-progressive MS were evaluated with the following 3T contrasts: 3D-T1-weighted, quantitative T1, FLAIR and magnetization-transfer, and 2D proton density- and T2-weighted. The following 7T contrasts were used: 3D-T1-weighted, quantitative T1, and 2D-T2*-weighted. Cortical lesion counts at 7T were the following: 720 total cortical lesions, 420 leukocortical lesions (58%), 27 intracortical lesions (4%), and 273 subpial lesions (38%). Cortical lesion counts at 3T were the following: 424 total cortical, 393 leukocortical (93%), 0intracortical, and 31 subpial (7%) lesions. Total, intracortical, and subpial 3T lesion counts were significantly lower than the 7Tcounts. The authors conclude that detection of leukocortical lesions at 3T is comparable with that at 7T MR imaging. Imaging at 3T is less sensitive to intracortical and subpial lesions.
Derraz, I.
- InterventionalYou have accessAntiplatelet Therapy in Patients with Aneurysmal SAH: Impact on Delayed Cerebral Ischemia and Clinical Outcome. A Meta-AnalysisF. Cagnazzo, I. Derraz, P.-H. Lefevre, G. Gascou, C. Dargazanli, C. Riquelme, P. Perrini, D. di Carlo, A. Bonafe and V. CostalatAmerican Journal of Neuroradiology July 2019, 40 (7) 1201-1206; DOI: https://doi.org/10.3174/ajnr.A6086
Deschamps, R.
- FELLOWS' JOURNAL CLUBAdult BrainYou have accessDiagnosis and Prediction of Relapses in Susac Syndrome: A New Use for MR Postcontrast FLAIR Leptomeningeal EnhancementS. Coulette, A. Lecler, E. Saragoussi, K. Zuber, J. Savatovsky, R. Deschamps, O. Gout, C. Sabben, J. Aboab, A. Affortit, F. Charbonneau and M. ObadiaAmerican Journal of Neuroradiology July 2019, 40 (7) 1184-1190; DOI: https://doi.org/10.3174/ajnr.A6103
From January 2011 to December 2017, nine consecutive patients with Susac syndrome and a control group of 73 patients with multiple sclerosis or clinically isolated syndrome were included. Two neuroradiologists blinded to the clinical and ophthalmologic data independently reviewed MRIs and assessed leptomeningeal enhancement and parenchymal abnormalities. Follow-up MRIs of patients with Susac syndrome were reviewed and compared with clinical and retinal fluorescein angiographic data evaluated by an independent ophthalmologist. Patients with Susac syndrome were significantly more likely to present with leptomeningeal enhancement: 5/9 (56%) versus 6/73 (8%) in the control group. They had a significantly higher leptomeningeal enhancement burden with ≥3 lesions in 5/9 patients versus 0/73. Regions of leptomeningeal enhancement were significantly more likely to be located in the posterior fossa. The authors conclude that leptomeningeal enhancement occurs frequently in Susac syndrome and could be helpful for diagnosis and prediction of clinical relapse.
Devinsky, O.
- FELLOWS' JOURNAL CLUBAdult BrainOpen Access3T MRI Whole-Brain Microscopy Discrimination of Subcortical Anatomy, Part 2: Basal ForebrainM.J. Hoch, M.T. Bruno, A. Faustin, N. Cruz, A.Y. Mogilner, L. Crandall, T. Wisniewski, O. Devinsky and T.M. ShepherdAmerican Journal of Neuroradiology July 2019, 40 (7) 1095-1105; DOI: https://doi.org/10.3174/ajnr.A6088
The authors applied an optimized TSE T2 sequence to washed whole postmortem brain samples (n=13) to demonstrate and characterize the detailed anatomy of the basal forebrain using a clinical 3T MR imaging scanner. Theyidentified most basal ganglia and diencephalon structures using serial axial, coronal, and sagittal planes relative to the intercommissural plane. Specific oblique image orientations demonstrated the positions and anatomic relationships for selected structures of interest to functional neurosurgery.
di Carlo, D.
- InterventionalYou have accessAntiplatelet Therapy in Patients with Aneurysmal SAH: Impact on Delayed Cerebral Ischemia and Clinical Outcome. A Meta-AnalysisF. Cagnazzo, I. Derraz, P.-H. Lefevre, G. Gascou, C. Dargazanli, C. Riquelme, P. Perrini, D. di Carlo, A. Bonafe and V. CostalatAmerican Journal of Neuroradiology July 2019, 40 (7) 1201-1206; DOI: https://doi.org/10.3174/ajnr.A6086
Dirks, P.
- EDITOR'S CHOICEPediatricsYou have accessPredictive Value of MRI in Diagnosing Brain AVM Recurrence after Angiographically Documented Exclusion in ChildrenA. Jhaveri, A. Amirabadi, P. Dirks, A.V. Kulkarni, M.M. Shroff, N. Shkumat, T. Krings, V.M. Pereira, V. Rea and P. MuthusamiAmerican Journal of Neuroradiology July 2019, 40 (7) 1227-1235; DOI: https://doi.org/10.3174/ajnr.A6093
The authors sought to determine the predictive values of contrast-enhanced MR imaging and TOF-MRA for brain AVM recurrence in children, compared with conventional angiography, in 39 patients (mean 10.8 years of age, mean Spetzler-Martin grade, 1.9). Features predictive of recurrence included a tuft of vessels on TOF-MRA and nodular juxtamural/linear enhancement with a draining vein on contrast-enhanced MR imaging. MR imaging is useful for surveillance after brain AVM treatment in children, but conventional angiography is required for definitive diagnosis of recurrence. TOF-MRA and contrast-enhanced MR imaging provide complementary information for determining brain AVM recurrence and should be interpreted in conjunction.
Distefano, D.
- EDITOR'S CHOICEAdult BrainYou have accessBrain Tumor-Enhancement Visualization and Morphometric Assessment: A Comparison of MPRAGE, SPACE, and VIBE MRI TechniquesL. Danieli, G.C. Riccitelli, D. Distefano, E. Prodi, E. Ventura, A. Cianfoni, A. Kaelin-Lang, M. Reinert and E. PravatàAmerican Journal of Neuroradiology July 2019, 40 (7) 1140-1148; DOI: https://doi.org/10.3174/ajnr.A6096
Fifty-four contrast-enhancing tumors (38 gliomas and 16 metastases) were assessed using MPRAGE, VIBE, and SPACE techniques randomly acquired after gadolinium-based contrast agent administration on a 3T scanner. Enhancement conspicuity was assessed quantitatively by calculating the contrast rate and contrast-to-noise ratio, and qualitatively, by consensus visual comparative ratings. Compared with MPRAGE, both SPACE and VIBE obtained higher contrast rate, contrast-to-noise ratio, and visual conspicuity ratings in both gliomas and metastases. The authors conclude that superior conspicuity for brain tumor enhancement can be achieved using SPACE and VIBE techniques, compared with MPRAGE.
E
Elliott, C.
- EDITOR'S CHOICEAdult BrainOpen AccessComparison of Multiple Sclerosis Cortical Lesion Types Detected by Multicontrast 3T and 7T MRIJ. Maranzano, M. Dadar, D.A. Rudko, D. De Nigris, C. Elliott, J.S. Gati, S.A. Morrow, R.S. Menon, D.L. Collins, D.L. Arnold and S. NarayananAmerican Journal of Neuroradiology July 2019, 40 (7) 1162-1169; DOI: https://doi.org/10.3174/ajnr.A6099
The aim of the authors was: 1) to compare multicontrast cortical lesion detection using 3T and 7T MR imaging, 2) to compare cortical lesion type frequency in relapsing-remitting and secondary-progressive MS, and 3) to assess whether detectability is related to the magnetization transfer ratio, an imaging marker sensitive to myelin content. Multicontrast 3T and 7T MR images from 10 patients with relapsing-remitting MS and 10 with secondary-progressive MS were evaluated with the following 3T contrasts: 3D-T1-weighted, quantitative T1, FLAIR and magnetization-transfer, and 2D proton density- and T2-weighted. The following 7T contrasts were used: 3D-T1-weighted, quantitative T1, and 2D-T2*-weighted. Cortical lesion counts at 7T were the following: 720 total cortical lesions, 420 leukocortical lesions (58%), 27 intracortical lesions (4%), and 273 subpial lesions (38%). Cortical lesion counts at 3T were the following: 424 total cortical, 393 leukocortical (93%), 0intracortical, and 31 subpial (7%) lesions. Total, intracortical, and subpial 3T lesion counts were significantly lower than the 7Tcounts. The authors conclude that detection of leukocortical lesions at 3T is comparable with that at 7T MR imaging. Imaging at 3T is less sensitive to intracortical and subpial lesions.
El Methni, J.
- Adult BrainYou have accessImproving Detection of Multiple Sclerosis Lesions in the Posterior Fossa Using an Optimized 3D-FLAIR Sequence at 3TA. Lecler, I. El Sanharawi, J. El Methni, O. Gout, P. Koskas and J. SavatovskyAmerican Journal of Neuroradiology July 2019, 40 (7) 1170-1176; DOI: https://doi.org/10.3174/ajnr.A6107
El Sanharawi, I.
- Adult BrainYou have accessImproving Detection of Multiple Sclerosis Lesions in the Posterior Fossa Using an Optimized 3D-FLAIR Sequence at 3TA. Lecler, I. El Sanharawi, J. El Methni, O. Gout, P. Koskas and J. SavatovskyAmerican Journal of Neuroradiology July 2019, 40 (7) 1170-1176; DOI: https://doi.org/10.3174/ajnr.A6107
F
Fadul, C.E.
- Adult BrainYou have accessExtent of Surgical Resection in Lower-Grade Gliomas: Differential Impact Based on Molecular SubtypeS.H. Patel, A.G. Bansal, E.B. Young, P.P. Batchala, J.T. Patrie, M.B. Lopes, R. Jain, C.E. Fadul and D. SchiffAmerican Journal of Neuroradiology July 2019, 40 (7) 1149-1155; DOI: https://doi.org/10.3174/ajnr.A6102
Fakhran, S.
- Adult BrainOpen AccessAssessing Postconcussive Reaction Time Using Transport-Based Morphometry of Diffusion Tensor ImagesS. Kundu, A. Ghodadra, S. Fakhran, L.M. Alhilali and G.K. RohdeAmerican Journal of Neuroradiology July 2019, 40 (7) 1117-1123; DOI: https://doi.org/10.3174/ajnr.A6087
Faustin, A.
- FELLOWS' JOURNAL CLUBAdult BrainOpen Access3T MRI Whole-Brain Microscopy Discrimination of Subcortical Anatomy, Part 2: Basal ForebrainM.J. Hoch, M.T. Bruno, A. Faustin, N. Cruz, A.Y. Mogilner, L. Crandall, T. Wisniewski, O. Devinsky and T.M. ShepherdAmerican Journal of Neuroradiology July 2019, 40 (7) 1095-1105; DOI: https://doi.org/10.3174/ajnr.A6088
The authors applied an optimized TSE T2 sequence to washed whole postmortem brain samples (n=13) to demonstrate and characterize the detailed anatomy of the basal forebrain using a clinical 3T MR imaging scanner. Theyidentified most basal ganglia and diencephalon structures using serial axial, coronal, and sagittal planes relative to the intercommissural plane. Specific oblique image orientations demonstrated the positions and anatomic relationships for selected structures of interest to functional neurosurgery.
Feiler, H.R.
- SpineYou have accessQuantification of DTI in the Pediatric Spinal Cord: Application to Clinical Evaluation in a Healthy Patient PopulationB.B. Reynolds, S. By, Q.R. Weinberg, A.A. Witt, A.T. Newton, H.R. Feiler, B. Ramkorun, D.B. Clayton, P. Couture, J.E. Martus, M. Adams, J.C. Wellons, S.A. Smith and A. BhatiaAmerican Journal of Neuroradiology July 2019, 40 (7) 1236-1241; DOI: https://doi.org/10.3174/ajnr.A6104
Forsting, M.
- Adult BrainYou have accessWall Contrast Enhancement of Thrombosed Intracranial Aneurysms at 7T MRIT. Sato, T. Matsushige, B. Chen, O. Gembruch, P. Dammann, R. Jabbarli, M. Forsting, A. Junker, S. Maderwald, H.H. Quick, M.E. Ladd, U. Sure and K.H. WredeAmerican Journal of Neuroradiology July 2019, 40 (7) 1106-1111; DOI: https://doi.org/10.3174/ajnr.A6084
Fujinaka, T.
- FELLOWS' JOURNAL CLUBInterventionalYou have accessLong-Term Results and Follow-Up Examinations after Endovascular Embolization for Unruptured Cerebral AneurysmsT. Murakami, T. Nishida, K. Asai, Y. Kadono, H. Nakamura, T. Fujinaka and H. KishimaAmerican Journal of Neuroradiology July 2019, 40 (7) 1191-1196; DOI: https://doi.org/10.3174/ajnr.A6101
The appropriate period of follow-up examinations after endovascular embolization for cerebral aneurysms using time-of-flight MR angiography is not well-known. Between April 2006 and March 2011, one hundred forty-eight unruptured aneurysms were treated with endovascular coil embolization. Among them, the authors investigated 116 unruptured aneurysms, which were followed up for >5 years. Time-of-flight MRA was performed at 1 day, 3–6 months, 1 year after the procedure, and every year thereafter. The mean follow-up period was 7.0 years. Recanalization was observed in 19 (16.3%) aneurysms within 2 years. Among them, retreatment was performed in 8 (6.8%) aneurysms. No recanalization was detected in any aneurysms that had been stable in the first 2 years after embolization. They conclude that aneurysms in which recanalization was not observed within 2 years after endovascular coil embolization were stable during a mean follow-up of 7 years. This result may be helpful in considering the appropriate span or frequency of follow-up imaging for embolized cerebral aneurysms.
G
Gascou, G.
- InterventionalYou have accessAntiplatelet Therapy in Patients with Aneurysmal SAH: Impact on Delayed Cerebral Ischemia and Clinical Outcome. A Meta-AnalysisF. Cagnazzo, I. Derraz, P.-H. Lefevre, G. Gascou, C. Dargazanli, C. Riquelme, P. Perrini, D. di Carlo, A. Bonafe and V. CostalatAmerican Journal of Neuroradiology July 2019, 40 (7) 1201-1206; DOI: https://doi.org/10.3174/ajnr.A6086
Gastala, J.
- FunctionalOpen AccessA Practical Review of Functional MRI Anatomy of the Language and Motor SystemsV.B. Hill, C.Z. Cankurtaran, B.P. Liu, T.A. Hijaz, M. Naidich, A.J. Nemeth, J. Gastala, C. Krumpelman, E.N. McComb and A.W. KorutzAmerican Journal of Neuroradiology July 2019, 40 (7) 1084-1090; DOI: https://doi.org/10.3174/ajnr.A6089
Gati, J.S.
- EDITOR'S CHOICEAdult BrainOpen AccessComparison of Multiple Sclerosis Cortical Lesion Types Detected by Multicontrast 3T and 7T MRIJ. Maranzano, M. Dadar, D.A. Rudko, D. De Nigris, C. Elliott, J.S. Gati, S.A. Morrow, R.S. Menon, D.L. Collins, D.L. Arnold and S. NarayananAmerican Journal of Neuroradiology July 2019, 40 (7) 1162-1169; DOI: https://doi.org/10.3174/ajnr.A6099
The aim of the authors was: 1) to compare multicontrast cortical lesion detection using 3T and 7T MR imaging, 2) to compare cortical lesion type frequency in relapsing-remitting and secondary-progressive MS, and 3) to assess whether detectability is related to the magnetization transfer ratio, an imaging marker sensitive to myelin content. Multicontrast 3T and 7T MR images from 10 patients with relapsing-remitting MS and 10 with secondary-progressive MS were evaluated with the following 3T contrasts: 3D-T1-weighted, quantitative T1, FLAIR and magnetization-transfer, and 2D proton density- and T2-weighted. The following 7T contrasts were used: 3D-T1-weighted, quantitative T1, and 2D-T2*-weighted. Cortical lesion counts at 7T were the following: 720 total cortical lesions, 420 leukocortical lesions (58%), 27 intracortical lesions (4%), and 273 subpial lesions (38%). Cortical lesion counts at 3T were the following: 424 total cortical, 393 leukocortical (93%), 0intracortical, and 31 subpial (7%) lesions. Total, intracortical, and subpial 3T lesion counts were significantly lower than the 7Tcounts. The authors conclude that detection of leukocortical lesions at 3T is comparable with that at 7T MR imaging. Imaging at 3T is less sensitive to intracortical and subpial lesions.
Ge, X.
- Adult BrainOpen AccessAssociation of Fractional Flow on 3D-TOF-MRA with Cerebral Perfusion in Patients with MCA StenosisX. Ge, H. Zhao, Z. Zhou, X. Li, B. Sun, H. Wu, J. Wan, J. Xu, J.P. Villablanca and X. LiuAmerican Journal of Neuroradiology July 2019, 40 (7) 1124-1131; DOI: https://doi.org/10.3174/ajnr.A6095
Gembruch, O.
- Adult BrainYou have accessWall Contrast Enhancement of Thrombosed Intracranial Aneurysms at 7T MRIT. Sato, T. Matsushige, B. Chen, O. Gembruch, P. Dammann, R. Jabbarli, M. Forsting, A. Junker, S. Maderwald, H.H. Quick, M.E. Ladd, U. Sure and K.H. WredeAmerican Journal of Neuroradiology July 2019, 40 (7) 1106-1111; DOI: https://doi.org/10.3174/ajnr.A6084
Ghodadra, A.
- Adult BrainOpen AccessAssessing Postconcussive Reaction Time Using Transport-Based Morphometry of Diffusion Tensor ImagesS. Kundu, A. Ghodadra, S. Fakhran, L.M. Alhilali and G.K. RohdeAmerican Journal of Neuroradiology July 2019, 40 (7) 1117-1123; DOI: https://doi.org/10.3174/ajnr.A6087
Gout, O.
- Adult BrainYou have accessImproving Detection of Multiple Sclerosis Lesions in the Posterior Fossa Using an Optimized 3D-FLAIR Sequence at 3TA. Lecler, I. El Sanharawi, J. El Methni, O. Gout, P. Koskas and J. SavatovskyAmerican Journal of Neuroradiology July 2019, 40 (7) 1170-1176; DOI: https://doi.org/10.3174/ajnr.A6107
- FELLOWS' JOURNAL CLUBAdult BrainYou have accessDiagnosis and Prediction of Relapses in Susac Syndrome: A New Use for MR Postcontrast FLAIR Leptomeningeal EnhancementS. Coulette, A. Lecler, E. Saragoussi, K. Zuber, J. Savatovsky, R. Deschamps, O. Gout, C. Sabben, J. Aboab, A. Affortit, F. Charbonneau and M. ObadiaAmerican Journal of Neuroradiology July 2019, 40 (7) 1184-1190; DOI: https://doi.org/10.3174/ajnr.A6103
From January 2011 to December 2017, nine consecutive patients with Susac syndrome and a control group of 73 patients with multiple sclerosis or clinically isolated syndrome were included. Two neuroradiologists blinded to the clinical and ophthalmologic data independently reviewed MRIs and assessed leptomeningeal enhancement and parenchymal abnormalities. Follow-up MRIs of patients with Susac syndrome were reviewed and compared with clinical and retinal fluorescein angiographic data evaluated by an independent ophthalmologist. Patients with Susac syndrome were significantly more likely to present with leptomeningeal enhancement: 5/9 (56%) versus 6/73 (8%) in the control group. They had a significantly higher leptomeningeal enhancement burden with ≥3 lesions in 5/9 patients versus 0/73. Regions of leptomeningeal enhancement were significantly more likely to be located in the posterior fossa. The authors conclude that leptomeningeal enhancement occurs frequently in Susac syndrome and could be helpful for diagnosis and prediction of clinical relapse.
Gutiérrez-Montes, C.
- SpineYou have accessSubject-Specific Studies of CSF Bulk Flow Patterns in the Spinal Canal: Implications for the Dispersion of Solute Particles in Intrathecal Drug DeliveryW. Coenen, C. Gutiérrez-Montes, S. Sincomb, E. Criado-Hidalgo, K. Wei, K. King, V. Haughton, C. Martínez-Bazán, A.L. Sánchez and J. C. LasherasAmerican Journal of Neuroradiology July 2019, 40 (7) 1242-1249; DOI: https://doi.org/10.3174/ajnr.A6097
H
Haughton, V.
- SpineYou have accessSubject-Specific Studies of CSF Bulk Flow Patterns in the Spinal Canal: Implications for the Dispersion of Solute Particles in Intrathecal Drug DeliveryW. Coenen, C. Gutiérrez-Montes, S. Sincomb, E. Criado-Hidalgo, K. Wei, K. King, V. Haughton, C. Martínez-Bazán, A.L. Sánchez and J. C. LasherasAmerican Journal of Neuroradiology July 2019, 40 (7) 1242-1249; DOI: https://doi.org/10.3174/ajnr.A6097
Hendrikse, J.
- Adult BrainYou have accessGadolinium Enhancement of the Aneurysm Wall in Unruptured Intracranial Aneurysms Is Associated with an Increased Risk of Aneurysm Instability: A Follow-Up StudyM.D.I. Vergouwen, D. Backes, I.C. van der Schaaf, J. Hendrikse, R. Kleinloog, A. Algra and G.J.E. RinkelAmerican Journal of Neuroradiology July 2019, 40 (7) 1112-1116; DOI: https://doi.org/10.3174/ajnr.A6105
Hijaz, T.A.
- FunctionalOpen AccessA Practical Review of Functional MRI Anatomy of the Language and Motor SystemsV.B. Hill, C.Z. Cankurtaran, B.P. Liu, T.A. Hijaz, M. Naidich, A.J. Nemeth, J. Gastala, C. Krumpelman, E.N. McComb and A.W. KorutzAmerican Journal of Neuroradiology July 2019, 40 (7) 1084-1090; DOI: https://doi.org/10.3174/ajnr.A6089
Hill, V.B.
- FunctionalOpen AccessA Practical Review of Functional MRI Anatomy of the Language and Motor SystemsV.B. Hill, C.Z. Cankurtaran, B.P. Liu, T.A. Hijaz, M. Naidich, A.J. Nemeth, J. Gastala, C. Krumpelman, E.N. McComb and A.W. KorutzAmerican Journal of Neuroradiology July 2019, 40 (7) 1084-1090; DOI: https://doi.org/10.3174/ajnr.A6089
Hoch, M.J.
- FELLOWS' JOURNAL CLUBAdult BrainOpen Access3T MRI Whole-Brain Microscopy Discrimination of Subcortical Anatomy, Part 2: Basal ForebrainM.J. Hoch, M.T. Bruno, A. Faustin, N. Cruz, A.Y. Mogilner, L. Crandall, T. Wisniewski, O. Devinsky and T.M. ShepherdAmerican Journal of Neuroradiology July 2019, 40 (7) 1095-1105; DOI: https://doi.org/10.3174/ajnr.A6088
The authors applied an optimized TSE T2 sequence to washed whole postmortem brain samples (n=13) to demonstrate and characterize the detailed anatomy of the basal forebrain using a clinical 3T MR imaging scanner. Theyidentified most basal ganglia and diencephalon structures using serial axial, coronal, and sagittal planes relative to the intercommissural plane. Specific oblique image orientations demonstrated the positions and anatomic relationships for selected structures of interest to functional neurosurgery.
Hopkins, L.N.
- InterventionalYou have accessFlow-Pattern Details in an Aneurysm Model Using High-Speed 1000-Frames-per-Second AngiographyJ.M. Krebs, A. Shankar, S.V. Setlur Nagesh, J.M. Davies, K.V. Snyder, E.I. Levy, L.N. Hopkins, M. Mokin, D.R. Bednarek, A.H. Siddiqui and S. RudinAmerican Journal of Neuroradiology July 2019, 40 (7) 1197-1200; DOI: https://doi.org/10.3174/ajnr.A6090
Hu, Y.C.
- LETTERYou have accessPolymer Embolism from Bioactive and Hydrogel Coil Embolization Technology: Considerations for Product DevelopmentA.M. Chopra, J.P. Cruz and Y.C. HuAmerican Journal of Neuroradiology July 2019, 40 (7) E34-E35; DOI: https://doi.org/10.3174/ajnr.A6083
J
Jabbarli, R.
- Adult BrainYou have accessWall Contrast Enhancement of Thrombosed Intracranial Aneurysms at 7T MRIT. Sato, T. Matsushige, B. Chen, O. Gembruch, P. Dammann, R. Jabbarli, M. Forsting, A. Junker, S. Maderwald, H.H. Quick, M.E. Ladd, U. Sure and K.H. WredeAmerican Journal of Neuroradiology July 2019, 40 (7) 1106-1111; DOI: https://doi.org/10.3174/ajnr.A6084
Jahromi, B.S.
- Extracranial VascularYou have accessComparison of Carotid Endarterectomy and Stenting for Symptomatic Internal Carotid Artery Near-OcclusionJ. Kim, S. Male, D. Damania, B.S. Jahromi and R.P. TummalaAmerican Journal of Neuroradiology July 2019, 40 (7) 1207-1212; DOI: https://doi.org/10.3174/ajnr.A6085
Jain, R.
- Adult BrainYou have accessExtent of Surgical Resection in Lower-Grade Gliomas: Differential Impact Based on Molecular SubtypeS.H. Patel, A.G. Bansal, E.B. Young, P.P. Batchala, J.T. Patrie, M.B. Lopes, R. Jain, C.E. Fadul and D. SchiffAmerican Journal of Neuroradiology July 2019, 40 (7) 1149-1155; DOI: https://doi.org/10.3174/ajnr.A6102
Jensen, T.R.
- Adult BrainOpen AccessQuantitative Delta T1 (dT1) as a Replacement for Adjudicated Central Reader Analysis of Contrast-Enhancing Tumor Burden: A Subanalysis of the American College of Radiology Imaging Network 6677/Radiation Therapy Oncology Group 0625 Multicenter Brain Tumor TrialK.M. Schmainda, M.A. Prah, Z. Zhang, B.S. Snyder, S.D. Rand, T.R. Jensen, D.P. Barboriak and J.L. BoxermanAmerican Journal of Neuroradiology July 2019, 40 (7) 1132-1139; DOI: https://doi.org/10.3174/ajnr.A6110
Jhaveri, A.
- EDITOR'S CHOICEPediatricsYou have accessPredictive Value of MRI in Diagnosing Brain AVM Recurrence after Angiographically Documented Exclusion in ChildrenA. Jhaveri, A. Amirabadi, P. Dirks, A.V. Kulkarni, M.M. Shroff, N. Shkumat, T. Krings, V.M. Pereira, V. Rea and P. MuthusamiAmerican Journal of Neuroradiology July 2019, 40 (7) 1227-1235; DOI: https://doi.org/10.3174/ajnr.A6093
The authors sought to determine the predictive values of contrast-enhanced MR imaging and TOF-MRA for brain AVM recurrence in children, compared with conventional angiography, in 39 patients (mean 10.8 years of age, mean Spetzler-Martin grade, 1.9). Features predictive of recurrence included a tuft of vessels on TOF-MRA and nodular juxtamural/linear enhancement with a draining vein on contrast-enhanced MR imaging. MR imaging is useful for surveillance after brain AVM treatment in children, but conventional angiography is required for definitive diagnosis of recurrence. TOF-MRA and contrast-enhanced MR imaging provide complementary information for determining brain AVM recurrence and should be interpreted in conjunction.
Junker, A.
- Adult BrainYou have accessWall Contrast Enhancement of Thrombosed Intracranial Aneurysms at 7T MRIT. Sato, T. Matsushige, B. Chen, O. Gembruch, P. Dammann, R. Jabbarli, M. Forsting, A. Junker, S. Maderwald, H.H. Quick, M.E. Ladd, U. Sure and K.H. WredeAmerican Journal of Neuroradiology July 2019, 40 (7) 1106-1111; DOI: https://doi.org/10.3174/ajnr.A6084
K
Kadono, Y.
- FELLOWS' JOURNAL CLUBInterventionalYou have accessLong-Term Results and Follow-Up Examinations after Endovascular Embolization for Unruptured Cerebral AneurysmsT. Murakami, T. Nishida, K. Asai, Y. Kadono, H. Nakamura, T. Fujinaka and H. KishimaAmerican Journal of Neuroradiology July 2019, 40 (7) 1191-1196; DOI: https://doi.org/10.3174/ajnr.A6101
The appropriate period of follow-up examinations after endovascular embolization for cerebral aneurysms using time-of-flight MR angiography is not well-known. Between April 2006 and March 2011, one hundred forty-eight unruptured aneurysms were treated with endovascular coil embolization. Among them, the authors investigated 116 unruptured aneurysms, which were followed up for >5 years. Time-of-flight MRA was performed at 1 day, 3–6 months, 1 year after the procedure, and every year thereafter. The mean follow-up period was 7.0 years. Recanalization was observed in 19 (16.3%) aneurysms within 2 years. Among them, retreatment was performed in 8 (6.8%) aneurysms. No recanalization was detected in any aneurysms that had been stable in the first 2 years after embolization. They conclude that aneurysms in which recanalization was not observed within 2 years after endovascular coil embolization were stable during a mean follow-up of 7 years. This result may be helpful in considering the appropriate span or frequency of follow-up imaging for embolized cerebral aneurysms.
Kaelin-Lang, A.
- EDITOR'S CHOICEAdult BrainYou have accessBrain Tumor-Enhancement Visualization and Morphometric Assessment: A Comparison of MPRAGE, SPACE, and VIBE MRI TechniquesL. Danieli, G.C. Riccitelli, D. Distefano, E. Prodi, E. Ventura, A. Cianfoni, A. Kaelin-Lang, M. Reinert and E. PravatàAmerican Journal of Neuroradiology July 2019, 40 (7) 1140-1148; DOI: https://doi.org/10.3174/ajnr.A6096
Fifty-four contrast-enhancing tumors (38 gliomas and 16 metastases) were assessed using MPRAGE, VIBE, and SPACE techniques randomly acquired after gadolinium-based contrast agent administration on a 3T scanner. Enhancement conspicuity was assessed quantitatively by calculating the contrast rate and contrast-to-noise ratio, and qualitatively, by consensus visual comparative ratings. Compared with MPRAGE, both SPACE and VIBE obtained higher contrast rate, contrast-to-noise ratio, and visual conspicuity ratings in both gliomas and metastases. The authors conclude that superior conspicuity for brain tumor enhancement can be achieved using SPACE and VIBE techniques, compared with MPRAGE.
Kames, C.
- PediatricsYou have accessQuantitative Analysis of Punctate White Matter Lesions in Neonates Using Quantitative Susceptibility Mapping and R2* RelaxationY. Zhang, A. Rauscher, C. Kames and A.M. WeberAmerican Journal of Neuroradiology July 2019, 40 (7) 1221-1226; DOI: https://doi.org/10.3174/ajnr.A6114
Kavanagh, Eoin C.
- You have accessPerspectivesEoin C. KavanaghAmerican Journal of Neuroradiology July 2019, 40 (7) 1083; DOI: https://doi.org/10.3174/ajnr.P0078
Kennedy, T.A.
- LETTERYou have accessReply:T.A. KennedyAmerican Journal of Neuroradiology July 2019, 40 (7) E37; DOI: https://doi.org/10.3174/ajnr.A6094
Key, S.R.
- You have accessAssessment of Explicitly Stated Interval Change on Noncontrast Head CT Radiology ReportsM. Braileanu, K. Crawford, S.R. Key and M.E. MullinsAmerican Journal of Neuroradiology July 2019, 40 (7) 1091-1094; DOI: https://doi.org/10.3174/ajnr.A6081
Kim, J.
- Extracranial VascularYou have accessComparison of Carotid Endarterectomy and Stenting for Symptomatic Internal Carotid Artery Near-OcclusionJ. Kim, S. Male, D. Damania, B.S. Jahromi and R.P. TummalaAmerican Journal of Neuroradiology July 2019, 40 (7) 1207-1212; DOI: https://doi.org/10.3174/ajnr.A6085
King, K.
- SpineYou have accessSubject-Specific Studies of CSF Bulk Flow Patterns in the Spinal Canal: Implications for the Dispersion of Solute Particles in Intrathecal Drug DeliveryW. Coenen, C. Gutiérrez-Montes, S. Sincomb, E. Criado-Hidalgo, K. Wei, K. King, V. Haughton, C. Martínez-Bazán, A.L. Sánchez and J. C. LasherasAmerican Journal of Neuroradiology July 2019, 40 (7) 1242-1249; DOI: https://doi.org/10.3174/ajnr.A6097
Kishima, H.
- FELLOWS' JOURNAL CLUBInterventionalYou have accessLong-Term Results and Follow-Up Examinations after Endovascular Embolization for Unruptured Cerebral AneurysmsT. Murakami, T. Nishida, K. Asai, Y. Kadono, H. Nakamura, T. Fujinaka and H. KishimaAmerican Journal of Neuroradiology July 2019, 40 (7) 1191-1196; DOI: https://doi.org/10.3174/ajnr.A6101
The appropriate period of follow-up examinations after endovascular embolization for cerebral aneurysms using time-of-flight MR angiography is not well-known. Between April 2006 and March 2011, one hundred forty-eight unruptured aneurysms were treated with endovascular coil embolization. Among them, the authors investigated 116 unruptured aneurysms, which were followed up for >5 years. Time-of-flight MRA was performed at 1 day, 3–6 months, 1 year after the procedure, and every year thereafter. The mean follow-up period was 7.0 years. Recanalization was observed in 19 (16.3%) aneurysms within 2 years. Among them, retreatment was performed in 8 (6.8%) aneurysms. No recanalization was detected in any aneurysms that had been stable in the first 2 years after embolization. They conclude that aneurysms in which recanalization was not observed within 2 years after endovascular coil embolization were stable during a mean follow-up of 7 years. This result may be helpful in considering the appropriate span or frequency of follow-up imaging for embolized cerebral aneurysms.
Kleinloog, R.
- Adult BrainYou have accessGadolinium Enhancement of the Aneurysm Wall in Unruptured Intracranial Aneurysms Is Associated with an Increased Risk of Aneurysm Instability: A Follow-Up StudyM.D.I. Vergouwen, D. Backes, I.C. van der Schaaf, J. Hendrikse, R. Kleinloog, A. Algra and G.J.E. RinkelAmerican Journal of Neuroradiology July 2019, 40 (7) 1112-1116; DOI: https://doi.org/10.3174/ajnr.A6105
Korutz, A.W.
- FunctionalOpen AccessA Practical Review of Functional MRI Anatomy of the Language and Motor SystemsV.B. Hill, C.Z. Cankurtaran, B.P. Liu, T.A. Hijaz, M. Naidich, A.J. Nemeth, J. Gastala, C. Krumpelman, E.N. McComb and A.W. KorutzAmerican Journal of Neuroradiology July 2019, 40 (7) 1084-1090; DOI: https://doi.org/10.3174/ajnr.A6089
Koskas, P.
- Adult BrainYou have accessImproving Detection of Multiple Sclerosis Lesions in the Posterior Fossa Using an Optimized 3D-FLAIR Sequence at 3TA. Lecler, I. El Sanharawi, J. El Methni, O. Gout, P. Koskas and J. SavatovskyAmerican Journal of Neuroradiology July 2019, 40 (7) 1170-1176; DOI: https://doi.org/10.3174/ajnr.A6107
Krebs, J.M.
- InterventionalYou have accessFlow-Pattern Details in an Aneurysm Model Using High-Speed 1000-Frames-per-Second AngiographyJ.M. Krebs, A. Shankar, S.V. Setlur Nagesh, J.M. Davies, K.V. Snyder, E.I. Levy, L.N. Hopkins, M. Mokin, D.R. Bednarek, A.H. Siddiqui and S. RudinAmerican Journal of Neuroradiology July 2019, 40 (7) 1197-1200; DOI: https://doi.org/10.3174/ajnr.A6090
Krings, T.
- EDITOR'S CHOICEPediatricsYou have accessPredictive Value of MRI in Diagnosing Brain AVM Recurrence after Angiographically Documented Exclusion in ChildrenA. Jhaveri, A. Amirabadi, P. Dirks, A.V. Kulkarni, M.M. Shroff, N. Shkumat, T. Krings, V.M. Pereira, V. Rea and P. MuthusamiAmerican Journal of Neuroradiology July 2019, 40 (7) 1227-1235; DOI: https://doi.org/10.3174/ajnr.A6093
The authors sought to determine the predictive values of contrast-enhanced MR imaging and TOF-MRA for brain AVM recurrence in children, compared with conventional angiography, in 39 patients (mean 10.8 years of age, mean Spetzler-Martin grade, 1.9). Features predictive of recurrence included a tuft of vessels on TOF-MRA and nodular juxtamural/linear enhancement with a draining vein on contrast-enhanced MR imaging. MR imaging is useful for surveillance after brain AVM treatment in children, but conventional angiography is required for definitive diagnosis of recurrence. TOF-MRA and contrast-enhanced MR imaging provide complementary information for determining brain AVM recurrence and should be interpreted in conjunction.
Krumpelman, C.
- FunctionalOpen AccessA Practical Review of Functional MRI Anatomy of the Language and Motor SystemsV.B. Hill, C.Z. Cankurtaran, B.P. Liu, T.A. Hijaz, M. Naidich, A.J. Nemeth, J. Gastala, C. Krumpelman, E.N. McComb and A.W. KorutzAmerican Journal of Neuroradiology July 2019, 40 (7) 1084-1090; DOI: https://doi.org/10.3174/ajnr.A6089
Kulkarni, A.V.
- EDITOR'S CHOICEPediatricsYou have accessPredictive Value of MRI in Diagnosing Brain AVM Recurrence after Angiographically Documented Exclusion in ChildrenA. Jhaveri, A. Amirabadi, P. Dirks, A.V. Kulkarni, M.M. Shroff, N. Shkumat, T. Krings, V.M. Pereira, V. Rea and P. MuthusamiAmerican Journal of Neuroradiology July 2019, 40 (7) 1227-1235; DOI: https://doi.org/10.3174/ajnr.A6093
The authors sought to determine the predictive values of contrast-enhanced MR imaging and TOF-MRA for brain AVM recurrence in children, compared with conventional angiography, in 39 patients (mean 10.8 years of age, mean Spetzler-Martin grade, 1.9). Features predictive of recurrence included a tuft of vessels on TOF-MRA and nodular juxtamural/linear enhancement with a draining vein on contrast-enhanced MR imaging. MR imaging is useful for surveillance after brain AVM treatment in children, but conventional angiography is required for definitive diagnosis of recurrence. TOF-MRA and contrast-enhanced MR imaging provide complementary information for determining brain AVM recurrence and should be interpreted in conjunction.
Kundu, S.
- Adult BrainOpen AccessAssessing Postconcussive Reaction Time Using Transport-Based Morphometry of Diffusion Tensor ImagesS. Kundu, A. Ghodadra, S. Fakhran, L.M. Alhilali and G.K. RohdeAmerican Journal of Neuroradiology July 2019, 40 (7) 1117-1123; DOI: https://doi.org/10.3174/ajnr.A6087
L
Ladd, M.E.
- Adult BrainYou have accessWall Contrast Enhancement of Thrombosed Intracranial Aneurysms at 7T MRIT. Sato, T. Matsushige, B. Chen, O. Gembruch, P. Dammann, R. Jabbarli, M. Forsting, A. Junker, S. Maderwald, H.H. Quick, M.E. Ladd, U. Sure and K.H. WredeAmerican Journal of Neuroradiology July 2019, 40 (7) 1106-1111; DOI: https://doi.org/10.3174/ajnr.A6084
Lasheras, J. C.
- SpineYou have accessSubject-Specific Studies of CSF Bulk Flow Patterns in the Spinal Canal: Implications for the Dispersion of Solute Particles in Intrathecal Drug DeliveryW. Coenen, C. Gutiérrez-Montes, S. Sincomb, E. Criado-Hidalgo, K. Wei, K. King, V. Haughton, C. Martínez-Bazán, A.L. Sánchez and J. C. LasherasAmerican Journal of Neuroradiology July 2019, 40 (7) 1242-1249; DOI: https://doi.org/10.3174/ajnr.A6097
Lecler, A.
- Adult BrainYou have accessImproving Detection of Multiple Sclerosis Lesions in the Posterior Fossa Using an Optimized 3D-FLAIR Sequence at 3TA. Lecler, I. El Sanharawi, J. El Methni, O. Gout, P. Koskas and J. SavatovskyAmerican Journal of Neuroradiology July 2019, 40 (7) 1170-1176; DOI: https://doi.org/10.3174/ajnr.A6107
- FELLOWS' JOURNAL CLUBAdult BrainYou have accessDiagnosis and Prediction of Relapses in Susac Syndrome: A New Use for MR Postcontrast FLAIR Leptomeningeal EnhancementS. Coulette, A. Lecler, E. Saragoussi, K. Zuber, J. Savatovsky, R. Deschamps, O. Gout, C. Sabben, J. Aboab, A. Affortit, F. Charbonneau and M. ObadiaAmerican Journal of Neuroradiology July 2019, 40 (7) 1184-1190; DOI: https://doi.org/10.3174/ajnr.A6103
From January 2011 to December 2017, nine consecutive patients with Susac syndrome and a control group of 73 patients with multiple sclerosis or clinically isolated syndrome were included. Two neuroradiologists blinded to the clinical and ophthalmologic data independently reviewed MRIs and assessed leptomeningeal enhancement and parenchymal abnormalities. Follow-up MRIs of patients with Susac syndrome were reviewed and compared with clinical and retinal fluorescein angiographic data evaluated by an independent ophthalmologist. Patients with Susac syndrome were significantly more likely to present with leptomeningeal enhancement: 5/9 (56%) versus 6/73 (8%) in the control group. They had a significantly higher leptomeningeal enhancement burden with ≥3 lesions in 5/9 patients versus 0/73. Regions of leptomeningeal enhancement were significantly more likely to be located in the posterior fossa. The authors conclude that leptomeningeal enhancement occurs frequently in Susac syndrome and could be helpful for diagnosis and prediction of clinical relapse.
Lefevre, P.-H.
- InterventionalYou have accessAntiplatelet Therapy in Patients with Aneurysmal SAH: Impact on Delayed Cerebral Ischemia and Clinical Outcome. A Meta-AnalysisF. Cagnazzo, I. Derraz, P.-H. Lefevre, G. Gascou, C. Dargazanli, C. Riquelme, P. Perrini, D. di Carlo, A. Bonafe and V. CostalatAmerican Journal of Neuroradiology July 2019, 40 (7) 1201-1206; DOI: https://doi.org/10.3174/ajnr.A6086
Levy, E.I.
- InterventionalYou have accessFlow-Pattern Details in an Aneurysm Model Using High-Speed 1000-Frames-per-Second AngiographyJ.M. Krebs, A. Shankar, S.V. Setlur Nagesh, J.M. Davies, K.V. Snyder, E.I. Levy, L.N. Hopkins, M. Mokin, D.R. Bednarek, A.H. Siddiqui and S. RudinAmerican Journal of Neuroradiology July 2019, 40 (7) 1197-1200; DOI: https://doi.org/10.3174/ajnr.A6090
Li, X.
- Adult BrainOpen AccessAssociation of Fractional Flow on 3D-TOF-MRA with Cerebral Perfusion in Patients with MCA StenosisX. Ge, H. Zhao, Z. Zhou, X. Li, B. Sun, H. Wu, J. Wan, J. Xu, J.P. Villablanca and X. LiuAmerican Journal of Neuroradiology July 2019, 40 (7) 1124-1131; DOI: https://doi.org/10.3174/ajnr.A6095
Liu, B.P.
- FunctionalOpen AccessA Practical Review of Functional MRI Anatomy of the Language and Motor SystemsV.B. Hill, C.Z. Cankurtaran, B.P. Liu, T.A. Hijaz, M. Naidich, A.J. Nemeth, J. Gastala, C. Krumpelman, E.N. McComb and A.W. KorutzAmerican Journal of Neuroradiology July 2019, 40 (7) 1084-1090; DOI: https://doi.org/10.3174/ajnr.A6089
Liu, X.
- Adult BrainOpen AccessAssociation of Fractional Flow on 3D-TOF-MRA with Cerebral Perfusion in Patients with MCA StenosisX. Ge, H. Zhao, Z. Zhou, X. Li, B. Sun, H. Wu, J. Wan, J. Xu, J.P. Villablanca and X. LiuAmerican Journal of Neuroradiology July 2019, 40 (7) 1124-1131; DOI: https://doi.org/10.3174/ajnr.A6095
Lopes, M.B.
- Adult BrainYou have accessExtent of Surgical Resection in Lower-Grade Gliomas: Differential Impact Based on Molecular SubtypeS.H. Patel, A.G. Bansal, E.B. Young, P.P. Batchala, J.T. Patrie, M.B. Lopes, R. Jain, C.E. Fadul and D. SchiffAmerican Journal of Neuroradiology July 2019, 40 (7) 1149-1155; DOI: https://doi.org/10.3174/ajnr.A6102
M
Maderwald, S.
- Adult BrainYou have accessWall Contrast Enhancement of Thrombosed Intracranial Aneurysms at 7T MRIT. Sato, T. Matsushige, B. Chen, O. Gembruch, P. Dammann, R. Jabbarli, M. Forsting, A. Junker, S. Maderwald, H.H. Quick, M.E. Ladd, U. Sure and K.H. WredeAmerican Journal of Neuroradiology July 2019, 40 (7) 1106-1111; DOI: https://doi.org/10.3174/ajnr.A6084
Maia, A.C.M.
- Adult BrainYou have accessImpact of Skull Defects on the Role of CTA for Brain Death ConfirmationD.M. Nunes, A.C.M. Maia, R.C. Boni and A.J. da RochaAmerican Journal of Neuroradiology July 2019, 40 (7) 1177-1183; DOI: https://doi.org/10.3174/ajnr.A6100
Male, S.
- Extracranial VascularYou have accessComparison of Carotid Endarterectomy and Stenting for Symptomatic Internal Carotid Artery Near-OcclusionJ. Kim, S. Male, D. Damania, B.S. Jahromi and R.P. TummalaAmerican Journal of Neuroradiology July 2019, 40 (7) 1207-1212; DOI: https://doi.org/10.3174/ajnr.A6085
Maranzano, J.
- EDITOR'S CHOICEAdult BrainOpen AccessComparison of Multiple Sclerosis Cortical Lesion Types Detected by Multicontrast 3T and 7T MRIJ. Maranzano, M. Dadar, D.A. Rudko, D. De Nigris, C. Elliott, J.S. Gati, S.A. Morrow, R.S. Menon, D.L. Collins, D.L. Arnold and S. NarayananAmerican Journal of Neuroradiology July 2019, 40 (7) 1162-1169; DOI: https://doi.org/10.3174/ajnr.A6099
The aim of the authors was: 1) to compare multicontrast cortical lesion detection using 3T and 7T MR imaging, 2) to compare cortical lesion type frequency in relapsing-remitting and secondary-progressive MS, and 3) to assess whether detectability is related to the magnetization transfer ratio, an imaging marker sensitive to myelin content. Multicontrast 3T and 7T MR images from 10 patients with relapsing-remitting MS and 10 with secondary-progressive MS were evaluated with the following 3T contrasts: 3D-T1-weighted, quantitative T1, FLAIR and magnetization-transfer, and 2D proton density- and T2-weighted. The following 7T contrasts were used: 3D-T1-weighted, quantitative T1, and 2D-T2*-weighted. Cortical lesion counts at 7T were the following: 720 total cortical lesions, 420 leukocortical lesions (58%), 27 intracortical lesions (4%), and 273 subpial lesions (38%). Cortical lesion counts at 3T were the following: 424 total cortical, 393 leukocortical (93%), 0intracortical, and 31 subpial (7%) lesions. Total, intracortical, and subpial 3T lesion counts were significantly lower than the 7Tcounts. The authors conclude that detection of leukocortical lesions at 3T is comparable with that at 7T MR imaging. Imaging at 3T is less sensitive to intracortical and subpial lesions.
Martínez-Bazán, C.
- SpineYou have accessSubject-Specific Studies of CSF Bulk Flow Patterns in the Spinal Canal: Implications for the Dispersion of Solute Particles in Intrathecal Drug DeliveryW. Coenen, C. Gutiérrez-Montes, S. Sincomb, E. Criado-Hidalgo, K. Wei, K. King, V. Haughton, C. Martínez-Bazán, A.L. Sánchez and J. C. LasherasAmerican Journal of Neuroradiology July 2019, 40 (7) 1242-1249; DOI: https://doi.org/10.3174/ajnr.A6097
Martus, J.E.
- SpineYou have accessQuantification of DTI in the Pediatric Spinal Cord: Application to Clinical Evaluation in a Healthy Patient PopulationB.B. Reynolds, S. By, Q.R. Weinberg, A.A. Witt, A.T. Newton, H.R. Feiler, B. Ramkorun, D.B. Clayton, P. Couture, J.E. Martus, M. Adams, J.C. Wellons, S.A. Smith and A. BhatiaAmerican Journal of Neuroradiology July 2019, 40 (7) 1236-1241; DOI: https://doi.org/10.3174/ajnr.A6104
Matsushige, T.
- Adult BrainYou have accessWall Contrast Enhancement of Thrombosed Intracranial Aneurysms at 7T MRIT. Sato, T. Matsushige, B. Chen, O. Gembruch, P. Dammann, R. Jabbarli, M. Forsting, A. Junker, S. Maderwald, H.H. Quick, M.E. Ladd, U. Sure and K.H. WredeAmerican Journal of Neuroradiology July 2019, 40 (7) 1106-1111; DOI: https://doi.org/10.3174/ajnr.A6084
McComb, E.N.
- FunctionalOpen AccessA Practical Review of Functional MRI Anatomy of the Language and Motor SystemsV.B. Hill, C.Z. Cankurtaran, B.P. Liu, T.A. Hijaz, M. Naidich, A.J. Nemeth, J. Gastala, C. Krumpelman, E.N. McComb and A.W. KorutzAmerican Journal of Neuroradiology July 2019, 40 (7) 1084-1090; DOI: https://doi.org/10.3174/ajnr.A6089
Menon, R.S.
- EDITOR'S CHOICEAdult BrainOpen AccessComparison of Multiple Sclerosis Cortical Lesion Types Detected by Multicontrast 3T and 7T MRIJ. Maranzano, M. Dadar, D.A. Rudko, D. De Nigris, C. Elliott, J.S. Gati, S.A. Morrow, R.S. Menon, D.L. Collins, D.L. Arnold and S. NarayananAmerican Journal of Neuroradiology July 2019, 40 (7) 1162-1169; DOI: https://doi.org/10.3174/ajnr.A6099
The aim of the authors was: 1) to compare multicontrast cortical lesion detection using 3T and 7T MR imaging, 2) to compare cortical lesion type frequency in relapsing-remitting and secondary-progressive MS, and 3) to assess whether detectability is related to the magnetization transfer ratio, an imaging marker sensitive to myelin content. Multicontrast 3T and 7T MR images from 10 patients with relapsing-remitting MS and 10 with secondary-progressive MS were evaluated with the following 3T contrasts: 3D-T1-weighted, quantitative T1, FLAIR and magnetization-transfer, and 2D proton density- and T2-weighted. The following 7T contrasts were used: 3D-T1-weighted, quantitative T1, and 2D-T2*-weighted. Cortical lesion counts at 7T were the following: 720 total cortical lesions, 420 leukocortical lesions (58%), 27 intracortical lesions (4%), and 273 subpial lesions (38%). Cortical lesion counts at 3T were the following: 424 total cortical, 393 leukocortical (93%), 0intracortical, and 31 subpial (7%) lesions. Total, intracortical, and subpial 3T lesion counts were significantly lower than the 7Tcounts. The authors conclude that detection of leukocortical lesions at 3T is comparable with that at 7T MR imaging. Imaging at 3T is less sensitive to intracortical and subpial lesions.
Mogilner, A.Y.
- FELLOWS' JOURNAL CLUBAdult BrainOpen Access3T MRI Whole-Brain Microscopy Discrimination of Subcortical Anatomy, Part 2: Basal ForebrainM.J. Hoch, M.T. Bruno, A. Faustin, N. Cruz, A.Y. Mogilner, L. Crandall, T. Wisniewski, O. Devinsky and T.M. ShepherdAmerican Journal of Neuroradiology July 2019, 40 (7) 1095-1105; DOI: https://doi.org/10.3174/ajnr.A6088
The authors applied an optimized TSE T2 sequence to washed whole postmortem brain samples (n=13) to demonstrate and characterize the detailed anatomy of the basal forebrain using a clinical 3T MR imaging scanner. Theyidentified most basal ganglia and diencephalon structures using serial axial, coronal, and sagittal planes relative to the intercommissural plane. Specific oblique image orientations demonstrated the positions and anatomic relationships for selected structures of interest to functional neurosurgery.
Mokin, M.
- InterventionalYou have accessFlow-Pattern Details in an Aneurysm Model Using High-Speed 1000-Frames-per-Second AngiographyJ.M. Krebs, A. Shankar, S.V. Setlur Nagesh, J.M. Davies, K.V. Snyder, E.I. Levy, L.N. Hopkins, M. Mokin, D.R. Bednarek, A.H. Siddiqui and S. RudinAmerican Journal of Neuroradiology July 2019, 40 (7) 1197-1200; DOI: https://doi.org/10.3174/ajnr.A6090
Morrow, S.A.
- EDITOR'S CHOICEAdult BrainOpen AccessComparison of Multiple Sclerosis Cortical Lesion Types Detected by Multicontrast 3T and 7T MRIJ. Maranzano, M. Dadar, D.A. Rudko, D. De Nigris, C. Elliott, J.S. Gati, S.A. Morrow, R.S. Menon, D.L. Collins, D.L. Arnold and S. NarayananAmerican Journal of Neuroradiology July 2019, 40 (7) 1162-1169; DOI: https://doi.org/10.3174/ajnr.A6099
The aim of the authors was: 1) to compare multicontrast cortical lesion detection using 3T and 7T MR imaging, 2) to compare cortical lesion type frequency in relapsing-remitting and secondary-progressive MS, and 3) to assess whether detectability is related to the magnetization transfer ratio, an imaging marker sensitive to myelin content. Multicontrast 3T and 7T MR images from 10 patients with relapsing-remitting MS and 10 with secondary-progressive MS were evaluated with the following 3T contrasts: 3D-T1-weighted, quantitative T1, FLAIR and magnetization-transfer, and 2D proton density- and T2-weighted. The following 7T contrasts were used: 3D-T1-weighted, quantitative T1, and 2D-T2*-weighted. Cortical lesion counts at 7T were the following: 720 total cortical lesions, 420 leukocortical lesions (58%), 27 intracortical lesions (4%), and 273 subpial lesions (38%). Cortical lesion counts at 3T were the following: 424 total cortical, 393 leukocortical (93%), 0intracortical, and 31 subpial (7%) lesions. Total, intracortical, and subpial 3T lesion counts were significantly lower than the 7Tcounts. The authors conclude that detection of leukocortical lesions at 3T is comparable with that at 7T MR imaging. Imaging at 3T is less sensitive to intracortical and subpial lesions.
Mullins, M.E.
- You have accessAssessment of Explicitly Stated Interval Change on Noncontrast Head CT Radiology ReportsM. Braileanu, K. Crawford, S.R. Key and M.E. MullinsAmerican Journal of Neuroradiology July 2019, 40 (7) 1091-1094; DOI: https://doi.org/10.3174/ajnr.A6081
Murakami, T.
- FELLOWS' JOURNAL CLUBInterventionalYou have accessLong-Term Results and Follow-Up Examinations after Endovascular Embolization for Unruptured Cerebral AneurysmsT. Murakami, T. Nishida, K. Asai, Y. Kadono, H. Nakamura, T. Fujinaka and H. KishimaAmerican Journal of Neuroradiology July 2019, 40 (7) 1191-1196; DOI: https://doi.org/10.3174/ajnr.A6101
The appropriate period of follow-up examinations after endovascular embolization for cerebral aneurysms using time-of-flight MR angiography is not well-known. Between April 2006 and March 2011, one hundred forty-eight unruptured aneurysms were treated with endovascular coil embolization. Among them, the authors investigated 116 unruptured aneurysms, which were followed up for >5 years. Time-of-flight MRA was performed at 1 day, 3–6 months, 1 year after the procedure, and every year thereafter. The mean follow-up period was 7.0 years. Recanalization was observed in 19 (16.3%) aneurysms within 2 years. Among them, retreatment was performed in 8 (6.8%) aneurysms. No recanalization was detected in any aneurysms that had been stable in the first 2 years after embolization. They conclude that aneurysms in which recanalization was not observed within 2 years after endovascular coil embolization were stable during a mean follow-up of 7 years. This result may be helpful in considering the appropriate span or frequency of follow-up imaging for embolized cerebral aneurysms.
Muthusami, P.
- EDITOR'S CHOICEPediatricsYou have accessPredictive Value of MRI in Diagnosing Brain AVM Recurrence after Angiographically Documented Exclusion in ChildrenA. Jhaveri, A. Amirabadi, P. Dirks, A.V. Kulkarni, M.M. Shroff, N. Shkumat, T. Krings, V.M. Pereira, V. Rea and P. MuthusamiAmerican Journal of Neuroradiology July 2019, 40 (7) 1227-1235; DOI: https://doi.org/10.3174/ajnr.A6093
The authors sought to determine the predictive values of contrast-enhanced MR imaging and TOF-MRA for brain AVM recurrence in children, compared with conventional angiography, in 39 patients (mean 10.8 years of age, mean Spetzler-Martin grade, 1.9). Features predictive of recurrence included a tuft of vessels on TOF-MRA and nodular juxtamural/linear enhancement with a draining vein on contrast-enhanced MR imaging. MR imaging is useful for surveillance after brain AVM treatment in children, but conventional angiography is required for definitive diagnosis of recurrence. TOF-MRA and contrast-enhanced MR imaging provide complementary information for determining brain AVM recurrence and should be interpreted in conjunction.
N
Naidich, M.
- FunctionalOpen AccessA Practical Review of Functional MRI Anatomy of the Language and Motor SystemsV.B. Hill, C.Z. Cankurtaran, B.P. Liu, T.A. Hijaz, M. Naidich, A.J. Nemeth, J. Gastala, C. Krumpelman, E.N. McComb and A.W. KorutzAmerican Journal of Neuroradiology July 2019, 40 (7) 1084-1090; DOI: https://doi.org/10.3174/ajnr.A6089
Nakamura, H.
- FELLOWS' JOURNAL CLUBInterventionalYou have accessLong-Term Results and Follow-Up Examinations after Endovascular Embolization for Unruptured Cerebral AneurysmsT. Murakami, T. Nishida, K. Asai, Y. Kadono, H. Nakamura, T. Fujinaka and H. KishimaAmerican Journal of Neuroradiology July 2019, 40 (7) 1191-1196; DOI: https://doi.org/10.3174/ajnr.A6101
The appropriate period of follow-up examinations after endovascular embolization for cerebral aneurysms using time-of-flight MR angiography is not well-known. Between April 2006 and March 2011, one hundred forty-eight unruptured aneurysms were treated with endovascular coil embolization. Among them, the authors investigated 116 unruptured aneurysms, which were followed up for >5 years. Time-of-flight MRA was performed at 1 day, 3–6 months, 1 year after the procedure, and every year thereafter. The mean follow-up period was 7.0 years. Recanalization was observed in 19 (16.3%) aneurysms within 2 years. Among them, retreatment was performed in 8 (6.8%) aneurysms. No recanalization was detected in any aneurysms that had been stable in the first 2 years after embolization. They conclude that aneurysms in which recanalization was not observed within 2 years after endovascular coil embolization were stable during a mean follow-up of 7 years. This result may be helpful in considering the appropriate span or frequency of follow-up imaging for embolized cerebral aneurysms.
Narayanan, S.
- EDITOR'S CHOICEAdult BrainOpen AccessComparison of Multiple Sclerosis Cortical Lesion Types Detected by Multicontrast 3T and 7T MRIJ. Maranzano, M. Dadar, D.A. Rudko, D. De Nigris, C. Elliott, J.S. Gati, S.A. Morrow, R.S. Menon, D.L. Collins, D.L. Arnold and S. NarayananAmerican Journal of Neuroradiology July 2019, 40 (7) 1162-1169; DOI: https://doi.org/10.3174/ajnr.A6099
The aim of the authors was: 1) to compare multicontrast cortical lesion detection using 3T and 7T MR imaging, 2) to compare cortical lesion type frequency in relapsing-remitting and secondary-progressive MS, and 3) to assess whether detectability is related to the magnetization transfer ratio, an imaging marker sensitive to myelin content. Multicontrast 3T and 7T MR images from 10 patients with relapsing-remitting MS and 10 with secondary-progressive MS were evaluated with the following 3T contrasts: 3D-T1-weighted, quantitative T1, FLAIR and magnetization-transfer, and 2D proton density- and T2-weighted. The following 7T contrasts were used: 3D-T1-weighted, quantitative T1, and 2D-T2*-weighted. Cortical lesion counts at 7T were the following: 720 total cortical lesions, 420 leukocortical lesions (58%), 27 intracortical lesions (4%), and 273 subpial lesions (38%). Cortical lesion counts at 3T were the following: 424 total cortical, 393 leukocortical (93%), 0intracortical, and 31 subpial (7%) lesions. Total, intracortical, and subpial 3T lesion counts were significantly lower than the 7Tcounts. The authors conclude that detection of leukocortical lesions at 3T is comparable with that at 7T MR imaging. Imaging at 3T is less sensitive to intracortical and subpial lesions.
Nawani, H.
- PediatricsYou have accessFunctional Connectivity Associated with Health-Related Quality of Life in Children with Focal EpilepsyH. Nawani, M.L. Smith, A.L. Wheeler and E. WidjajaAmerican Journal of Neuroradiology July 2019, 40 (7) 1213-1220; DOI: https://doi.org/10.3174/ajnr.A6106
Nemeth, A.J.
- FunctionalOpen AccessA Practical Review of Functional MRI Anatomy of the Language and Motor SystemsV.B. Hill, C.Z. Cankurtaran, B.P. Liu, T.A. Hijaz, M. Naidich, A.J. Nemeth, J. Gastala, C. Krumpelman, E.N. McComb and A.W. KorutzAmerican Journal of Neuroradiology July 2019, 40 (7) 1084-1090; DOI: https://doi.org/10.3174/ajnr.A6089
Newton, A.T.
- SpineYou have accessQuantification of DTI in the Pediatric Spinal Cord: Application to Clinical Evaluation in a Healthy Patient PopulationB.B. Reynolds, S. By, Q.R. Weinberg, A.A. Witt, A.T. Newton, H.R. Feiler, B. Ramkorun, D.B. Clayton, P. Couture, J.E. Martus, M. Adams, J.C. Wellons, S.A. Smith and A. BhatiaAmerican Journal of Neuroradiology July 2019, 40 (7) 1236-1241; DOI: https://doi.org/10.3174/ajnr.A6104
Nishida, T.
- FELLOWS' JOURNAL CLUBInterventionalYou have accessLong-Term Results and Follow-Up Examinations after Endovascular Embolization for Unruptured Cerebral AneurysmsT. Murakami, T. Nishida, K. Asai, Y. Kadono, H. Nakamura, T. Fujinaka and H. KishimaAmerican Journal of Neuroradiology July 2019, 40 (7) 1191-1196; DOI: https://doi.org/10.3174/ajnr.A6101
The appropriate period of follow-up examinations after endovascular embolization for cerebral aneurysms using time-of-flight MR angiography is not well-known. Between April 2006 and March 2011, one hundred forty-eight unruptured aneurysms were treated with endovascular coil embolization. Among them, the authors investigated 116 unruptured aneurysms, which were followed up for >5 years. Time-of-flight MRA was performed at 1 day, 3–6 months, 1 year after the procedure, and every year thereafter. The mean follow-up period was 7.0 years. Recanalization was observed in 19 (16.3%) aneurysms within 2 years. Among them, retreatment was performed in 8 (6.8%) aneurysms. No recanalization was detected in any aneurysms that had been stable in the first 2 years after embolization. They conclude that aneurysms in which recanalization was not observed within 2 years after endovascular coil embolization were stable during a mean follow-up of 7 years. This result may be helpful in considering the appropriate span or frequency of follow-up imaging for embolized cerebral aneurysms.
Nunes, D.M.
- Adult BrainYou have accessImpact of Skull Defects on the Role of CTA for Brain Death ConfirmationD.M. Nunes, A.C.M. Maia, R.C. Boni and A.J. da RochaAmerican Journal of Neuroradiology July 2019, 40 (7) 1177-1183; DOI: https://doi.org/10.3174/ajnr.A6100
O
Obadia, M.
- FELLOWS' JOURNAL CLUBAdult BrainYou have accessDiagnosis and Prediction of Relapses in Susac Syndrome: A New Use for MR Postcontrast FLAIR Leptomeningeal EnhancementS. Coulette, A. Lecler, E. Saragoussi, K. Zuber, J. Savatovsky, R. Deschamps, O. Gout, C. Sabben, J. Aboab, A. Affortit, F. Charbonneau and M. ObadiaAmerican Journal of Neuroradiology July 2019, 40 (7) 1184-1190; DOI: https://doi.org/10.3174/ajnr.A6103
From January 2011 to December 2017, nine consecutive patients with Susac syndrome and a control group of 73 patients with multiple sclerosis or clinically isolated syndrome were included. Two neuroradiologists blinded to the clinical and ophthalmologic data independently reviewed MRIs and assessed leptomeningeal enhancement and parenchymal abnormalities. Follow-up MRIs of patients with Susac syndrome were reviewed and compared with clinical and retinal fluorescein angiographic data evaluated by an independent ophthalmologist. Patients with Susac syndrome were significantly more likely to present with leptomeningeal enhancement: 5/9 (56%) versus 6/73 (8%) in the control group. They had a significantly higher leptomeningeal enhancement burden with ≥3 lesions in 5/9 patients versus 0/73. Regions of leptomeningeal enhancement were significantly more likely to be located in the posterior fossa. The authors conclude that leptomeningeal enhancement occurs frequently in Susac syndrome and could be helpful for diagnosis and prediction of clinical relapse.
P
Patel, S.H.
- Adult BrainYou have accessExtent of Surgical Resection in Lower-Grade Gliomas: Differential Impact Based on Molecular SubtypeS.H. Patel, A.G. Bansal, E.B. Young, P.P. Batchala, J.T. Patrie, M.B. Lopes, R. Jain, C.E. Fadul and D. SchiffAmerican Journal of Neuroradiology July 2019, 40 (7) 1149-1155; DOI: https://doi.org/10.3174/ajnr.A6102
Patrie, J.T.
- Adult BrainYou have accessExtent of Surgical Resection in Lower-Grade Gliomas: Differential Impact Based on Molecular SubtypeS.H. Patel, A.G. Bansal, E.B. Young, P.P. Batchala, J.T. Patrie, M.B. Lopes, R. Jain, C.E. Fadul and D. SchiffAmerican Journal of Neuroradiology July 2019, 40 (7) 1149-1155; DOI: https://doi.org/10.3174/ajnr.A6102
Pereira, V.M.
- EDITOR'S CHOICEPediatricsYou have accessPredictive Value of MRI in Diagnosing Brain AVM Recurrence after Angiographically Documented Exclusion in ChildrenA. Jhaveri, A. Amirabadi, P. Dirks, A.V. Kulkarni, M.M. Shroff, N. Shkumat, T. Krings, V.M. Pereira, V. Rea and P. MuthusamiAmerican Journal of Neuroradiology July 2019, 40 (7) 1227-1235; DOI: https://doi.org/10.3174/ajnr.A6093
The authors sought to determine the predictive values of contrast-enhanced MR imaging and TOF-MRA for brain AVM recurrence in children, compared with conventional angiography, in 39 patients (mean 10.8 years of age, mean Spetzler-Martin grade, 1.9). Features predictive of recurrence included a tuft of vessels on TOF-MRA and nodular juxtamural/linear enhancement with a draining vein on contrast-enhanced MR imaging. MR imaging is useful for surveillance after brain AVM treatment in children, but conventional angiography is required for definitive diagnosis of recurrence. TOF-MRA and contrast-enhanced MR imaging provide complementary information for determining brain AVM recurrence and should be interpreted in conjunction.
Perrini, P.
- InterventionalYou have accessAntiplatelet Therapy in Patients with Aneurysmal SAH: Impact on Delayed Cerebral Ischemia and Clinical Outcome. A Meta-AnalysisF. Cagnazzo, I. Derraz, P.-H. Lefevre, G. Gascou, C. Dargazanli, C. Riquelme, P. Perrini, D. di Carlo, A. Bonafe and V. CostalatAmerican Journal of Neuroradiology July 2019, 40 (7) 1201-1206; DOI: https://doi.org/10.3174/ajnr.A6086
Prah, M.A.
- Adult BrainOpen AccessQuantitative Delta T1 (dT1) as a Replacement for Adjudicated Central Reader Analysis of Contrast-Enhancing Tumor Burden: A Subanalysis of the American College of Radiology Imaging Network 6677/Radiation Therapy Oncology Group 0625 Multicenter Brain Tumor TrialK.M. Schmainda, M.A. Prah, Z. Zhang, B.S. Snyder, S.D. Rand, T.R. Jensen, D.P. Barboriak and J.L. BoxermanAmerican Journal of Neuroradiology July 2019, 40 (7) 1132-1139; DOI: https://doi.org/10.3174/ajnr.A6110
Pravatà, E.
- EDITOR'S CHOICEAdult BrainYou have accessBrain Tumor-Enhancement Visualization and Morphometric Assessment: A Comparison of MPRAGE, SPACE, and VIBE MRI TechniquesL. Danieli, G.C. Riccitelli, D. Distefano, E. Prodi, E. Ventura, A. Cianfoni, A. Kaelin-Lang, M. Reinert and E. PravatàAmerican Journal of Neuroradiology July 2019, 40 (7) 1140-1148; DOI: https://doi.org/10.3174/ajnr.A6096
Fifty-four contrast-enhancing tumors (38 gliomas and 16 metastases) were assessed using MPRAGE, VIBE, and SPACE techniques randomly acquired after gadolinium-based contrast agent administration on a 3T scanner. Enhancement conspicuity was assessed quantitatively by calculating the contrast rate and contrast-to-noise ratio, and qualitatively, by consensus visual comparative ratings. Compared with MPRAGE, both SPACE and VIBE obtained higher contrast rate, contrast-to-noise ratio, and visual conspicuity ratings in both gliomas and metastases. The authors conclude that superior conspicuity for brain tumor enhancement can be achieved using SPACE and VIBE techniques, compared with MPRAGE.
Prodi, E.
- EDITOR'S CHOICEAdult BrainYou have accessBrain Tumor-Enhancement Visualization and Morphometric Assessment: A Comparison of MPRAGE, SPACE, and VIBE MRI TechniquesL. Danieli, G.C. Riccitelli, D. Distefano, E. Prodi, E. Ventura, A. Cianfoni, A. Kaelin-Lang, M. Reinert and E. PravatàAmerican Journal of Neuroradiology July 2019, 40 (7) 1140-1148; DOI: https://doi.org/10.3174/ajnr.A6096
Fifty-four contrast-enhancing tumors (38 gliomas and 16 metastases) were assessed using MPRAGE, VIBE, and SPACE techniques randomly acquired after gadolinium-based contrast agent administration on a 3T scanner. Enhancement conspicuity was assessed quantitatively by calculating the contrast rate and contrast-to-noise ratio, and qualitatively, by consensus visual comparative ratings. Compared with MPRAGE, both SPACE and VIBE obtained higher contrast rate, contrast-to-noise ratio, and visual conspicuity ratings in both gliomas and metastases. The authors conclude that superior conspicuity for brain tumor enhancement can be achieved using SPACE and VIBE techniques, compared with MPRAGE.
Q
Qin, W.
- Adult BrainOpen AccessNormal-Appearing Cerebellar Damage in Neuromyelitis Optica Spectrum DisorderJ. Sun, N. Zhang, Q. Wang, X. Zhang, W. Qin, L. Yang, F.-D. Shi and C. YuAmerican Journal of Neuroradiology July 2019, 40 (7) 1156-1161; DOI: https://doi.org/10.3174/ajnr.A6098
Quick, H.H.
- Adult BrainYou have accessWall Contrast Enhancement of Thrombosed Intracranial Aneurysms at 7T MRIT. Sato, T. Matsushige, B. Chen, O. Gembruch, P. Dammann, R. Jabbarli, M. Forsting, A. Junker, S. Maderwald, H.H. Quick, M.E. Ladd, U. Sure and K.H. WredeAmerican Journal of Neuroradiology July 2019, 40 (7) 1106-1111; DOI: https://doi.org/10.3174/ajnr.A6084
R
Ramkorun, B.
- SpineYou have accessQuantification of DTI in the Pediatric Spinal Cord: Application to Clinical Evaluation in a Healthy Patient PopulationB.B. Reynolds, S. By, Q.R. Weinberg, A.A. Witt, A.T. Newton, H.R. Feiler, B. Ramkorun, D.B. Clayton, P. Couture, J.E. Martus, M. Adams, J.C. Wellons, S.A. Smith and A. BhatiaAmerican Journal of Neuroradiology July 2019, 40 (7) 1236-1241; DOI: https://doi.org/10.3174/ajnr.A6104
Rand, S.D.
- Adult BrainOpen AccessQuantitative Delta T1 (dT1) as a Replacement for Adjudicated Central Reader Analysis of Contrast-Enhancing Tumor Burden: A Subanalysis of the American College of Radiology Imaging Network 6677/Radiation Therapy Oncology Group 0625 Multicenter Brain Tumor TrialK.M. Schmainda, M.A. Prah, Z. Zhang, B.S. Snyder, S.D. Rand, T.R. Jensen, D.P. Barboriak and J.L. BoxermanAmerican Journal of Neuroradiology July 2019, 40 (7) 1132-1139; DOI: https://doi.org/10.3174/ajnr.A6110
Rauscher, A.
- PediatricsYou have accessQuantitative Analysis of Punctate White Matter Lesions in Neonates Using Quantitative Susceptibility Mapping and R2* RelaxationY. Zhang, A. Rauscher, C. Kames and A.M. WeberAmerican Journal of Neuroradiology July 2019, 40 (7) 1221-1226; DOI: https://doi.org/10.3174/ajnr.A6114
Rea, V.
- EDITOR'S CHOICEPediatricsYou have accessPredictive Value of MRI in Diagnosing Brain AVM Recurrence after Angiographically Documented Exclusion in ChildrenA. Jhaveri, A. Amirabadi, P. Dirks, A.V. Kulkarni, M.M. Shroff, N. Shkumat, T. Krings, V.M. Pereira, V. Rea and P. MuthusamiAmerican Journal of Neuroradiology July 2019, 40 (7) 1227-1235; DOI: https://doi.org/10.3174/ajnr.A6093
The authors sought to determine the predictive values of contrast-enhanced MR imaging and TOF-MRA for brain AVM recurrence in children, compared with conventional angiography, in 39 patients (mean 10.8 years of age, mean Spetzler-Martin grade, 1.9). Features predictive of recurrence included a tuft of vessels on TOF-MRA and nodular juxtamural/linear enhancement with a draining vein on contrast-enhanced MR imaging. MR imaging is useful for surveillance after brain AVM treatment in children, but conventional angiography is required for definitive diagnosis of recurrence. TOF-MRA and contrast-enhanced MR imaging provide complementary information for determining brain AVM recurrence and should be interpreted in conjunction.
Reinert, M.
- EDITOR'S CHOICEAdult BrainYou have accessBrain Tumor-Enhancement Visualization and Morphometric Assessment: A Comparison of MPRAGE, SPACE, and VIBE MRI TechniquesL. Danieli, G.C. Riccitelli, D. Distefano, E. Prodi, E. Ventura, A. Cianfoni, A. Kaelin-Lang, M. Reinert and E. PravatàAmerican Journal of Neuroradiology July 2019, 40 (7) 1140-1148; DOI: https://doi.org/10.3174/ajnr.A6096
Fifty-four contrast-enhancing tumors (38 gliomas and 16 metastases) were assessed using MPRAGE, VIBE, and SPACE techniques randomly acquired after gadolinium-based contrast agent administration on a 3T scanner. Enhancement conspicuity was assessed quantitatively by calculating the contrast rate and contrast-to-noise ratio, and qualitatively, by consensus visual comparative ratings. Compared with MPRAGE, both SPACE and VIBE obtained higher contrast rate, contrast-to-noise ratio, and visual conspicuity ratings in both gliomas and metastases. The authors conclude that superior conspicuity for brain tumor enhancement can be achieved using SPACE and VIBE techniques, compared with MPRAGE.
Reynolds, B.B.
- SpineYou have accessQuantification of DTI in the Pediatric Spinal Cord: Application to Clinical Evaluation in a Healthy Patient PopulationB.B. Reynolds, S. By, Q.R. Weinberg, A.A. Witt, A.T. Newton, H.R. Feiler, B. Ramkorun, D.B. Clayton, P. Couture, J.E. Martus, M. Adams, J.C. Wellons, S.A. Smith and A. BhatiaAmerican Journal of Neuroradiology July 2019, 40 (7) 1236-1241; DOI: https://doi.org/10.3174/ajnr.A6104
Riccitelli, G.C.
- EDITOR'S CHOICEAdult BrainYou have accessBrain Tumor-Enhancement Visualization and Morphometric Assessment: A Comparison of MPRAGE, SPACE, and VIBE MRI TechniquesL. Danieli, G.C. Riccitelli, D. Distefano, E. Prodi, E. Ventura, A. Cianfoni, A. Kaelin-Lang, M. Reinert and E. PravatàAmerican Journal of Neuroradiology July 2019, 40 (7) 1140-1148; DOI: https://doi.org/10.3174/ajnr.A6096
Fifty-four contrast-enhancing tumors (38 gliomas and 16 metastases) were assessed using MPRAGE, VIBE, and SPACE techniques randomly acquired after gadolinium-based contrast agent administration on a 3T scanner. Enhancement conspicuity was assessed quantitatively by calculating the contrast rate and contrast-to-noise ratio, and qualitatively, by consensus visual comparative ratings. Compared with MPRAGE, both SPACE and VIBE obtained higher contrast rate, contrast-to-noise ratio, and visual conspicuity ratings in both gliomas and metastases. The authors conclude that superior conspicuity for brain tumor enhancement can be achieved using SPACE and VIBE techniques, compared with MPRAGE.
Rinkel, G.J.E.
- Adult BrainYou have accessGadolinium Enhancement of the Aneurysm Wall in Unruptured Intracranial Aneurysms Is Associated with an Increased Risk of Aneurysm Instability: A Follow-Up StudyM.D.I. Vergouwen, D. Backes, I.C. van der Schaaf, J. Hendrikse, R. Kleinloog, A. Algra and G.J.E. RinkelAmerican Journal of Neuroradiology July 2019, 40 (7) 1112-1116; DOI: https://doi.org/10.3174/ajnr.A6105
Riquelme, C.
- InterventionalYou have accessAntiplatelet Therapy in Patients with Aneurysmal SAH: Impact on Delayed Cerebral Ischemia and Clinical Outcome. A Meta-AnalysisF. Cagnazzo, I. Derraz, P.-H. Lefevre, G. Gascou, C. Dargazanli, C. Riquelme, P. Perrini, D. di Carlo, A. Bonafe and V. CostalatAmerican Journal of Neuroradiology July 2019, 40 (7) 1201-1206; DOI: https://doi.org/10.3174/ajnr.A6086
Rohde, G.K.
- Adult BrainOpen AccessAssessing Postconcussive Reaction Time Using Transport-Based Morphometry of Diffusion Tensor ImagesS. Kundu, A. Ghodadra, S. Fakhran, L.M. Alhilali and G.K. RohdeAmerican Journal of Neuroradiology July 2019, 40 (7) 1117-1123; DOI: https://doi.org/10.3174/ajnr.A6087
Rosa, N.
- LETTERYou have accessOptic Nerve Evaluation in Idiopathic Intracranial HypertensionM. De Bernardo, L. Vitiello and N. RosaAmerican Journal of Neuroradiology July 2019, 40 (7) E36; DOI: https://doi.org/10.3174/ajnr.A6091
Rudin, S.
- InterventionalYou have accessFlow-Pattern Details in an Aneurysm Model Using High-Speed 1000-Frames-per-Second AngiographyJ.M. Krebs, A. Shankar, S.V. Setlur Nagesh, J.M. Davies, K.V. Snyder, E.I. Levy, L.N. Hopkins, M. Mokin, D.R. Bednarek, A.H. Siddiqui and S. RudinAmerican Journal of Neuroradiology July 2019, 40 (7) 1197-1200; DOI: https://doi.org/10.3174/ajnr.A6090
Rudko, D.A.
- EDITOR'S CHOICEAdult BrainOpen AccessComparison of Multiple Sclerosis Cortical Lesion Types Detected by Multicontrast 3T and 7T MRIJ. Maranzano, M. Dadar, D.A. Rudko, D. De Nigris, C. Elliott, J.S. Gati, S.A. Morrow, R.S. Menon, D.L. Collins, D.L. Arnold and S. NarayananAmerican Journal of Neuroradiology July 2019, 40 (7) 1162-1169; DOI: https://doi.org/10.3174/ajnr.A6099
The aim of the authors was: 1) to compare multicontrast cortical lesion detection using 3T and 7T MR imaging, 2) to compare cortical lesion type frequency in relapsing-remitting and secondary-progressive MS, and 3) to assess whether detectability is related to the magnetization transfer ratio, an imaging marker sensitive to myelin content. Multicontrast 3T and 7T MR images from 10 patients with relapsing-remitting MS and 10 with secondary-progressive MS were evaluated with the following 3T contrasts: 3D-T1-weighted, quantitative T1, FLAIR and magnetization-transfer, and 2D proton density- and T2-weighted. The following 7T contrasts were used: 3D-T1-weighted, quantitative T1, and 2D-T2*-weighted. Cortical lesion counts at 7T were the following: 720 total cortical lesions, 420 leukocortical lesions (58%), 27 intracortical lesions (4%), and 273 subpial lesions (38%). Cortical lesion counts at 3T were the following: 424 total cortical, 393 leukocortical (93%), 0intracortical, and 31 subpial (7%) lesions. Total, intracortical, and subpial 3T lesion counts were significantly lower than the 7Tcounts. The authors conclude that detection of leukocortical lesions at 3T is comparable with that at 7T MR imaging. Imaging at 3T is less sensitive to intracortical and subpial lesions.
S
Sabben, C.
- FELLOWS' JOURNAL CLUBAdult BrainYou have accessDiagnosis and Prediction of Relapses in Susac Syndrome: A New Use for MR Postcontrast FLAIR Leptomeningeal EnhancementS. Coulette, A. Lecler, E. Saragoussi, K. Zuber, J. Savatovsky, R. Deschamps, O. Gout, C. Sabben, J. Aboab, A. Affortit, F. Charbonneau and M. ObadiaAmerican Journal of Neuroradiology July 2019, 40 (7) 1184-1190; DOI: https://doi.org/10.3174/ajnr.A6103
From January 2011 to December 2017, nine consecutive patients with Susac syndrome and a control group of 73 patients with multiple sclerosis or clinically isolated syndrome were included. Two neuroradiologists blinded to the clinical and ophthalmologic data independently reviewed MRIs and assessed leptomeningeal enhancement and parenchymal abnormalities. Follow-up MRIs of patients with Susac syndrome were reviewed and compared with clinical and retinal fluorescein angiographic data evaluated by an independent ophthalmologist. Patients with Susac syndrome were significantly more likely to present with leptomeningeal enhancement: 5/9 (56%) versus 6/73 (8%) in the control group. They had a significantly higher leptomeningeal enhancement burden with ≥3 lesions in 5/9 patients versus 0/73. Regions of leptomeningeal enhancement were significantly more likely to be located in the posterior fossa. The authors conclude that leptomeningeal enhancement occurs frequently in Susac syndrome and could be helpful for diagnosis and prediction of clinical relapse.
Sánchez, A.L.
- SpineYou have accessSubject-Specific Studies of CSF Bulk Flow Patterns in the Spinal Canal: Implications for the Dispersion of Solute Particles in Intrathecal Drug DeliveryW. Coenen, C. Gutiérrez-Montes, S. Sincomb, E. Criado-Hidalgo, K. Wei, K. King, V. Haughton, C. Martínez-Bazán, A.L. Sánchez and J. C. LasherasAmerican Journal of Neuroradiology July 2019, 40 (7) 1242-1249; DOI: https://doi.org/10.3174/ajnr.A6097
Saragoussi, E.
- FELLOWS' JOURNAL CLUBAdult BrainYou have accessDiagnosis and Prediction of Relapses in Susac Syndrome: A New Use for MR Postcontrast FLAIR Leptomeningeal EnhancementS. Coulette, A. Lecler, E. Saragoussi, K. Zuber, J. Savatovsky, R. Deschamps, O. Gout, C. Sabben, J. Aboab, A. Affortit, F. Charbonneau and M. ObadiaAmerican Journal of Neuroradiology July 2019, 40 (7) 1184-1190; DOI: https://doi.org/10.3174/ajnr.A6103
From January 2011 to December 2017, nine consecutive patients with Susac syndrome and a control group of 73 patients with multiple sclerosis or clinically isolated syndrome were included. Two neuroradiologists blinded to the clinical and ophthalmologic data independently reviewed MRIs and assessed leptomeningeal enhancement and parenchymal abnormalities. Follow-up MRIs of patients with Susac syndrome were reviewed and compared with clinical and retinal fluorescein angiographic data evaluated by an independent ophthalmologist. Patients with Susac syndrome were significantly more likely to present with leptomeningeal enhancement: 5/9 (56%) versus 6/73 (8%) in the control group. They had a significantly higher leptomeningeal enhancement burden with ≥3 lesions in 5/9 patients versus 0/73. Regions of leptomeningeal enhancement were significantly more likely to be located in the posterior fossa. The authors conclude that leptomeningeal enhancement occurs frequently in Susac syndrome and could be helpful for diagnosis and prediction of clinical relapse.
Sato, T.
- Adult BrainYou have accessWall Contrast Enhancement of Thrombosed Intracranial Aneurysms at 7T MRIT. Sato, T. Matsushige, B. Chen, O. Gembruch, P. Dammann, R. Jabbarli, M. Forsting, A. Junker, S. Maderwald, H.H. Quick, M.E. Ladd, U. Sure and K.H. WredeAmerican Journal of Neuroradiology July 2019, 40 (7) 1106-1111; DOI: https://doi.org/10.3174/ajnr.A6084
Savatovsky, J.
- Adult BrainYou have accessImproving Detection of Multiple Sclerosis Lesions in the Posterior Fossa Using an Optimized 3D-FLAIR Sequence at 3TA. Lecler, I. El Sanharawi, J. El Methni, O. Gout, P. Koskas and J. SavatovskyAmerican Journal of Neuroradiology July 2019, 40 (7) 1170-1176; DOI: https://doi.org/10.3174/ajnr.A6107
- FELLOWS' JOURNAL CLUBAdult BrainYou have accessDiagnosis and Prediction of Relapses in Susac Syndrome: A New Use for MR Postcontrast FLAIR Leptomeningeal EnhancementS. Coulette, A. Lecler, E. Saragoussi, K. Zuber, J. Savatovsky, R. Deschamps, O. Gout, C. Sabben, J. Aboab, A. Affortit, F. Charbonneau and M. ObadiaAmerican Journal of Neuroradiology July 2019, 40 (7) 1184-1190; DOI: https://doi.org/10.3174/ajnr.A6103
From January 2011 to December 2017, nine consecutive patients with Susac syndrome and a control group of 73 patients with multiple sclerosis or clinically isolated syndrome were included. Two neuroradiologists blinded to the clinical and ophthalmologic data independently reviewed MRIs and assessed leptomeningeal enhancement and parenchymal abnormalities. Follow-up MRIs of patients with Susac syndrome were reviewed and compared with clinical and retinal fluorescein angiographic data evaluated by an independent ophthalmologist. Patients with Susac syndrome were significantly more likely to present with leptomeningeal enhancement: 5/9 (56%) versus 6/73 (8%) in the control group. They had a significantly higher leptomeningeal enhancement burden with ≥3 lesions in 5/9 patients versus 0/73. Regions of leptomeningeal enhancement were significantly more likely to be located in the posterior fossa. The authors conclude that leptomeningeal enhancement occurs frequently in Susac syndrome and could be helpful for diagnosis and prediction of clinical relapse.
Schiff, D.
- Adult BrainYou have accessExtent of Surgical Resection in Lower-Grade Gliomas: Differential Impact Based on Molecular SubtypeS.H. Patel, A.G. Bansal, E.B. Young, P.P. Batchala, J.T. Patrie, M.B. Lopes, R. Jain, C.E. Fadul and D. SchiffAmerican Journal of Neuroradiology July 2019, 40 (7) 1149-1155; DOI: https://doi.org/10.3174/ajnr.A6102
Schmainda, K.M.
- Adult BrainOpen AccessQuantitative Delta T1 (dT1) as a Replacement for Adjudicated Central Reader Analysis of Contrast-Enhancing Tumor Burden: A Subanalysis of the American College of Radiology Imaging Network 6677/Radiation Therapy Oncology Group 0625 Multicenter Brain Tumor TrialK.M. Schmainda, M.A. Prah, Z. Zhang, B.S. Snyder, S.D. Rand, T.R. Jensen, D.P. Barboriak and J.L. BoxermanAmerican Journal of Neuroradiology July 2019, 40 (7) 1132-1139; DOI: https://doi.org/10.3174/ajnr.A6110
Setlur Nagesh, S.V.
- InterventionalYou have accessFlow-Pattern Details in an Aneurysm Model Using High-Speed 1000-Frames-per-Second AngiographyJ.M. Krebs, A. Shankar, S.V. Setlur Nagesh, J.M. Davies, K.V. Snyder, E.I. Levy, L.N. Hopkins, M. Mokin, D.R. Bednarek, A.H. Siddiqui and S. RudinAmerican Journal of Neuroradiology July 2019, 40 (7) 1197-1200; DOI: https://doi.org/10.3174/ajnr.A6090
Shankar, A.
- InterventionalYou have accessFlow-Pattern Details in an Aneurysm Model Using High-Speed 1000-Frames-per-Second AngiographyJ.M. Krebs, A. Shankar, S.V. Setlur Nagesh, J.M. Davies, K.V. Snyder, E.I. Levy, L.N. Hopkins, M. Mokin, D.R. Bednarek, A.H. Siddiqui and S. RudinAmerican Journal of Neuroradiology July 2019, 40 (7) 1197-1200; DOI: https://doi.org/10.3174/ajnr.A6090
Shepherd, T.M.
- FELLOWS' JOURNAL CLUBAdult BrainOpen Access3T MRI Whole-Brain Microscopy Discrimination of Subcortical Anatomy, Part 2: Basal ForebrainM.J. Hoch, M.T. Bruno, A. Faustin, N. Cruz, A.Y. Mogilner, L. Crandall, T. Wisniewski, O. Devinsky and T.M. ShepherdAmerican Journal of Neuroradiology July 2019, 40 (7) 1095-1105; DOI: https://doi.org/10.3174/ajnr.A6088
The authors applied an optimized TSE T2 sequence to washed whole postmortem brain samples (n=13) to demonstrate and characterize the detailed anatomy of the basal forebrain using a clinical 3T MR imaging scanner. Theyidentified most basal ganglia and diencephalon structures using serial axial, coronal, and sagittal planes relative to the intercommissural plane. Specific oblique image orientations demonstrated the positions and anatomic relationships for selected structures of interest to functional neurosurgery.
Shi, F.-D.
- Adult BrainOpen AccessNormal-Appearing Cerebellar Damage in Neuromyelitis Optica Spectrum DisorderJ. Sun, N. Zhang, Q. Wang, X. Zhang, W. Qin, L. Yang, F.-D. Shi and C. YuAmerican Journal of Neuroradiology July 2019, 40 (7) 1156-1161; DOI: https://doi.org/10.3174/ajnr.A6098
Shkumat, N.
- EDITOR'S CHOICEPediatricsYou have accessPredictive Value of MRI in Diagnosing Brain AVM Recurrence after Angiographically Documented Exclusion in ChildrenA. Jhaveri, A. Amirabadi, P. Dirks, A.V. Kulkarni, M.M. Shroff, N. Shkumat, T. Krings, V.M. Pereira, V. Rea and P. MuthusamiAmerican Journal of Neuroradiology July 2019, 40 (7) 1227-1235; DOI: https://doi.org/10.3174/ajnr.A6093
The authors sought to determine the predictive values of contrast-enhanced MR imaging and TOF-MRA for brain AVM recurrence in children, compared with conventional angiography, in 39 patients (mean 10.8 years of age, mean Spetzler-Martin grade, 1.9). Features predictive of recurrence included a tuft of vessels on TOF-MRA and nodular juxtamural/linear enhancement with a draining vein on contrast-enhanced MR imaging. MR imaging is useful for surveillance after brain AVM treatment in children, but conventional angiography is required for definitive diagnosis of recurrence. TOF-MRA and contrast-enhanced MR imaging provide complementary information for determining brain AVM recurrence and should be interpreted in conjunction.
Shroff, M.M.
- EDITOR'S CHOICEPediatricsYou have accessPredictive Value of MRI in Diagnosing Brain AVM Recurrence after Angiographically Documented Exclusion in ChildrenA. Jhaveri, A. Amirabadi, P. Dirks, A.V. Kulkarni, M.M. Shroff, N. Shkumat, T. Krings, V.M. Pereira, V. Rea and P. MuthusamiAmerican Journal of Neuroradiology July 2019, 40 (7) 1227-1235; DOI: https://doi.org/10.3174/ajnr.A6093
The authors sought to determine the predictive values of contrast-enhanced MR imaging and TOF-MRA for brain AVM recurrence in children, compared with conventional angiography, in 39 patients (mean 10.8 years of age, mean Spetzler-Martin grade, 1.9). Features predictive of recurrence included a tuft of vessels on TOF-MRA and nodular juxtamural/linear enhancement with a draining vein on contrast-enhanced MR imaging. MR imaging is useful for surveillance after brain AVM treatment in children, but conventional angiography is required for definitive diagnosis of recurrence. TOF-MRA and contrast-enhanced MR imaging provide complementary information for determining brain AVM recurrence and should be interpreted in conjunction.
Siddiqui, A.H.
- InterventionalYou have accessFlow-Pattern Details in an Aneurysm Model Using High-Speed 1000-Frames-per-Second AngiographyJ.M. Krebs, A. Shankar, S.V. Setlur Nagesh, J.M. Davies, K.V. Snyder, E.I. Levy, L.N. Hopkins, M. Mokin, D.R. Bednarek, A.H. Siddiqui and S. RudinAmerican Journal of Neuroradiology July 2019, 40 (7) 1197-1200; DOI: https://doi.org/10.3174/ajnr.A6090
Sincomb, S.
- SpineYou have accessSubject-Specific Studies of CSF Bulk Flow Patterns in the Spinal Canal: Implications for the Dispersion of Solute Particles in Intrathecal Drug DeliveryW. Coenen, C. Gutiérrez-Montes, S. Sincomb, E. Criado-Hidalgo, K. Wei, K. King, V. Haughton, C. Martínez-Bazán, A.L. Sánchez and J. C. LasherasAmerican Journal of Neuroradiology July 2019, 40 (7) 1242-1249; DOI: https://doi.org/10.3174/ajnr.A6097
Smith, M.L.
- PediatricsYou have accessFunctional Connectivity Associated with Health-Related Quality of Life in Children with Focal EpilepsyH. Nawani, M.L. Smith, A.L. Wheeler and E. WidjajaAmerican Journal of Neuroradiology July 2019, 40 (7) 1213-1220; DOI: https://doi.org/10.3174/ajnr.A6106
Smith, S.A.
- SpineYou have accessQuantification of DTI in the Pediatric Spinal Cord: Application to Clinical Evaluation in a Healthy Patient PopulationB.B. Reynolds, S. By, Q.R. Weinberg, A.A. Witt, A.T. Newton, H.R. Feiler, B. Ramkorun, D.B. Clayton, P. Couture, J.E. Martus, M. Adams, J.C. Wellons, S.A. Smith and A. BhatiaAmerican Journal of Neuroradiology July 2019, 40 (7) 1236-1241; DOI: https://doi.org/10.3174/ajnr.A6104
Snyder, B.S.
- Adult BrainOpen AccessQuantitative Delta T1 (dT1) as a Replacement for Adjudicated Central Reader Analysis of Contrast-Enhancing Tumor Burden: A Subanalysis of the American College of Radiology Imaging Network 6677/Radiation Therapy Oncology Group 0625 Multicenter Brain Tumor TrialK.M. Schmainda, M.A. Prah, Z. Zhang, B.S. Snyder, S.D. Rand, T.R. Jensen, D.P. Barboriak and J.L. BoxermanAmerican Journal of Neuroradiology July 2019, 40 (7) 1132-1139; DOI: https://doi.org/10.3174/ajnr.A6110
Snyder, K.V.
- InterventionalYou have accessFlow-Pattern Details in an Aneurysm Model Using High-Speed 1000-Frames-per-Second AngiographyJ.M. Krebs, A. Shankar, S.V. Setlur Nagesh, J.M. Davies, K.V. Snyder, E.I. Levy, L.N. Hopkins, M. Mokin, D.R. Bednarek, A.H. Siddiqui and S. RudinAmerican Journal of Neuroradiology July 2019, 40 (7) 1197-1200; DOI: https://doi.org/10.3174/ajnr.A6090
Sun, B.
- Adult BrainOpen AccessAssociation of Fractional Flow on 3D-TOF-MRA with Cerebral Perfusion in Patients with MCA StenosisX. Ge, H. Zhao, Z. Zhou, X. Li, B. Sun, H. Wu, J. Wan, J. Xu, J.P. Villablanca and X. LiuAmerican Journal of Neuroradiology July 2019, 40 (7) 1124-1131; DOI: https://doi.org/10.3174/ajnr.A6095
Sun, J.
- Adult BrainOpen AccessNormal-Appearing Cerebellar Damage in Neuromyelitis Optica Spectrum DisorderJ. Sun, N. Zhang, Q. Wang, X. Zhang, W. Qin, L. Yang, F.-D. Shi and C. YuAmerican Journal of Neuroradiology July 2019, 40 (7) 1156-1161; DOI: https://doi.org/10.3174/ajnr.A6098
Sure, U.
- Adult BrainYou have accessWall Contrast Enhancement of Thrombosed Intracranial Aneurysms at 7T MRIT. Sato, T. Matsushige, B. Chen, O. Gembruch, P. Dammann, R. Jabbarli, M. Forsting, A. Junker, S. Maderwald, H.H. Quick, M.E. Ladd, U. Sure and K.H. WredeAmerican Journal of Neuroradiology July 2019, 40 (7) 1106-1111; DOI: https://doi.org/10.3174/ajnr.A6084
T
Tummala, R.P.
- Extracranial VascularYou have accessComparison of Carotid Endarterectomy and Stenting for Symptomatic Internal Carotid Artery Near-OcclusionJ. Kim, S. Male, D. Damania, B.S. Jahromi and R.P. TummalaAmerican Journal of Neuroradiology July 2019, 40 (7) 1207-1212; DOI: https://doi.org/10.3174/ajnr.A6085
V
van der Schaaf, I.C.
- Adult BrainYou have accessGadolinium Enhancement of the Aneurysm Wall in Unruptured Intracranial Aneurysms Is Associated with an Increased Risk of Aneurysm Instability: A Follow-Up StudyM.D.I. Vergouwen, D. Backes, I.C. van der Schaaf, J. Hendrikse, R. Kleinloog, A. Algra and G.J.E. RinkelAmerican Journal of Neuroradiology July 2019, 40 (7) 1112-1116; DOI: https://doi.org/10.3174/ajnr.A6105
Ventura, E.
- EDITOR'S CHOICEAdult BrainYou have accessBrain Tumor-Enhancement Visualization and Morphometric Assessment: A Comparison of MPRAGE, SPACE, and VIBE MRI TechniquesL. Danieli, G.C. Riccitelli, D. Distefano, E. Prodi, E. Ventura, A. Cianfoni, A. Kaelin-Lang, M. Reinert and E. PravatàAmerican Journal of Neuroradiology July 2019, 40 (7) 1140-1148; DOI: https://doi.org/10.3174/ajnr.A6096
Fifty-four contrast-enhancing tumors (38 gliomas and 16 metastases) were assessed using MPRAGE, VIBE, and SPACE techniques randomly acquired after gadolinium-based contrast agent administration on a 3T scanner. Enhancement conspicuity was assessed quantitatively by calculating the contrast rate and contrast-to-noise ratio, and qualitatively, by consensus visual comparative ratings. Compared with MPRAGE, both SPACE and VIBE obtained higher contrast rate, contrast-to-noise ratio, and visual conspicuity ratings in both gliomas and metastases. The authors conclude that superior conspicuity for brain tumor enhancement can be achieved using SPACE and VIBE techniques, compared with MPRAGE.
Vergouwen, M.D.I.
- Adult BrainYou have accessGadolinium Enhancement of the Aneurysm Wall in Unruptured Intracranial Aneurysms Is Associated with an Increased Risk of Aneurysm Instability: A Follow-Up StudyM.D.I. Vergouwen, D. Backes, I.C. van der Schaaf, J. Hendrikse, R. Kleinloog, A. Algra and G.J.E. RinkelAmerican Journal of Neuroradiology July 2019, 40 (7) 1112-1116; DOI: https://doi.org/10.3174/ajnr.A6105
Villablanca, J.P.
- Adult BrainOpen AccessAssociation of Fractional Flow on 3D-TOF-MRA with Cerebral Perfusion in Patients with MCA StenosisX. Ge, H. Zhao, Z. Zhou, X. Li, B. Sun, H. Wu, J. Wan, J. Xu, J.P. Villablanca and X. LiuAmerican Journal of Neuroradiology July 2019, 40 (7) 1124-1131; DOI: https://doi.org/10.3174/ajnr.A6095
Vitiello, L.
- LETTERYou have accessOptic Nerve Evaluation in Idiopathic Intracranial HypertensionM. De Bernardo, L. Vitiello and N. RosaAmerican Journal of Neuroradiology July 2019, 40 (7) E36; DOI: https://doi.org/10.3174/ajnr.A6091
W
Wan, J.
- Adult BrainOpen AccessAssociation of Fractional Flow on 3D-TOF-MRA with Cerebral Perfusion in Patients with MCA StenosisX. Ge, H. Zhao, Z. Zhou, X. Li, B. Sun, H. Wu, J. Wan, J. Xu, J.P. Villablanca and X. LiuAmerican Journal of Neuroradiology July 2019, 40 (7) 1124-1131; DOI: https://doi.org/10.3174/ajnr.A6095
Wang, Q.
- Adult BrainOpen AccessNormal-Appearing Cerebellar Damage in Neuromyelitis Optica Spectrum DisorderJ. Sun, N. Zhang, Q. Wang, X. Zhang, W. Qin, L. Yang, F.-D. Shi and C. YuAmerican Journal of Neuroradiology July 2019, 40 (7) 1156-1161; DOI: https://doi.org/10.3174/ajnr.A6098
Weber, A.M.
- PediatricsYou have accessQuantitative Analysis of Punctate White Matter Lesions in Neonates Using Quantitative Susceptibility Mapping and R2* RelaxationY. Zhang, A. Rauscher, C. Kames and A.M. WeberAmerican Journal of Neuroradiology July 2019, 40 (7) 1221-1226; DOI: https://doi.org/10.3174/ajnr.A6114
Wei, K.
- SpineYou have accessSubject-Specific Studies of CSF Bulk Flow Patterns in the Spinal Canal: Implications for the Dispersion of Solute Particles in Intrathecal Drug DeliveryW. Coenen, C. Gutiérrez-Montes, S. Sincomb, E. Criado-Hidalgo, K. Wei, K. King, V. Haughton, C. Martínez-Bazán, A.L. Sánchez and J. C. LasherasAmerican Journal of Neuroradiology July 2019, 40 (7) 1242-1249; DOI: https://doi.org/10.3174/ajnr.A6097
Weinberg, Q.R.
- SpineYou have accessQuantification of DTI in the Pediatric Spinal Cord: Application to Clinical Evaluation in a Healthy Patient PopulationB.B. Reynolds, S. By, Q.R. Weinberg, A.A. Witt, A.T. Newton, H.R. Feiler, B. Ramkorun, D.B. Clayton, P. Couture, J.E. Martus, M. Adams, J.C. Wellons, S.A. Smith and A. BhatiaAmerican Journal of Neuroradiology July 2019, 40 (7) 1236-1241; DOI: https://doi.org/10.3174/ajnr.A6104
Wellons, J.C.
- SpineYou have accessQuantification of DTI in the Pediatric Spinal Cord: Application to Clinical Evaluation in a Healthy Patient PopulationB.B. Reynolds, S. By, Q.R. Weinberg, A.A. Witt, A.T. Newton, H.R. Feiler, B. Ramkorun, D.B. Clayton, P. Couture, J.E. Martus, M. Adams, J.C. Wellons, S.A. Smith and A. BhatiaAmerican Journal of Neuroradiology July 2019, 40 (7) 1236-1241; DOI: https://doi.org/10.3174/ajnr.A6104
Wheeler, A.L.
- PediatricsYou have accessFunctional Connectivity Associated with Health-Related Quality of Life in Children with Focal EpilepsyH. Nawani, M.L. Smith, A.L. Wheeler and E. WidjajaAmerican Journal of Neuroradiology July 2019, 40 (7) 1213-1220; DOI: https://doi.org/10.3174/ajnr.A6106
Widjaja, E.
- PediatricsYou have accessFunctional Connectivity Associated with Health-Related Quality of Life in Children with Focal EpilepsyH. Nawani, M.L. Smith, A.L. Wheeler and E. WidjajaAmerican Journal of Neuroradiology July 2019, 40 (7) 1213-1220; DOI: https://doi.org/10.3174/ajnr.A6106
Wisniewski, T.
- FELLOWS' JOURNAL CLUBAdult BrainOpen Access3T MRI Whole-Brain Microscopy Discrimination of Subcortical Anatomy, Part 2: Basal ForebrainM.J. Hoch, M.T. Bruno, A. Faustin, N. Cruz, A.Y. Mogilner, L. Crandall, T. Wisniewski, O. Devinsky and T.M. ShepherdAmerican Journal of Neuroradiology July 2019, 40 (7) 1095-1105; DOI: https://doi.org/10.3174/ajnr.A6088
The authors applied an optimized TSE T2 sequence to washed whole postmortem brain samples (n=13) to demonstrate and characterize the detailed anatomy of the basal forebrain using a clinical 3T MR imaging scanner. Theyidentified most basal ganglia and diencephalon structures using serial axial, coronal, and sagittal planes relative to the intercommissural plane. Specific oblique image orientations demonstrated the positions and anatomic relationships for selected structures of interest to functional neurosurgery.
Witt, A.A.
- SpineYou have accessQuantification of DTI in the Pediatric Spinal Cord: Application to Clinical Evaluation in a Healthy Patient PopulationB.B. Reynolds, S. By, Q.R. Weinberg, A.A. Witt, A.T. Newton, H.R. Feiler, B. Ramkorun, D.B. Clayton, P. Couture, J.E. Martus, M. Adams, J.C. Wellons, S.A. Smith and A. BhatiaAmerican Journal of Neuroradiology July 2019, 40 (7) 1236-1241; DOI: https://doi.org/10.3174/ajnr.A6104
Wrede, K.H.
- Adult BrainYou have accessWall Contrast Enhancement of Thrombosed Intracranial Aneurysms at 7T MRIT. Sato, T. Matsushige, B. Chen, O. Gembruch, P. Dammann, R. Jabbarli, M. Forsting, A. Junker, S. Maderwald, H.H. Quick, M.E. Ladd, U. Sure and K.H. WredeAmerican Journal of Neuroradiology July 2019, 40 (7) 1106-1111; DOI: https://doi.org/10.3174/ajnr.A6084
Wu, H.
- Adult BrainOpen AccessAssociation of Fractional Flow on 3D-TOF-MRA with Cerebral Perfusion in Patients with MCA StenosisX. Ge, H. Zhao, Z. Zhou, X. Li, B. Sun, H. Wu, J. Wan, J. Xu, J.P. Villablanca and X. LiuAmerican Journal of Neuroradiology July 2019, 40 (7) 1124-1131; DOI: https://doi.org/10.3174/ajnr.A6095
X
Xu, J.
- Adult BrainOpen AccessAssociation of Fractional Flow on 3D-TOF-MRA with Cerebral Perfusion in Patients with MCA StenosisX. Ge, H. Zhao, Z. Zhou, X. Li, B. Sun, H. Wu, J. Wan, J. Xu, J.P. Villablanca and X. LiuAmerican Journal of Neuroradiology July 2019, 40 (7) 1124-1131; DOI: https://doi.org/10.3174/ajnr.A6095
Y
Yang, L.
- Adult BrainOpen AccessNormal-Appearing Cerebellar Damage in Neuromyelitis Optica Spectrum DisorderJ. Sun, N. Zhang, Q. Wang, X. Zhang, W. Qin, L. Yang, F.-D. Shi and C. YuAmerican Journal of Neuroradiology July 2019, 40 (7) 1156-1161; DOI: https://doi.org/10.3174/ajnr.A6098
Young, E.B.
- Adult BrainYou have accessExtent of Surgical Resection in Lower-Grade Gliomas: Differential Impact Based on Molecular SubtypeS.H. Patel, A.G. Bansal, E.B. Young, P.P. Batchala, J.T. Patrie, M.B. Lopes, R. Jain, C.E. Fadul and D. SchiffAmerican Journal of Neuroradiology July 2019, 40 (7) 1149-1155; DOI: https://doi.org/10.3174/ajnr.A6102
Yu, C.
- Adult BrainOpen AccessNormal-Appearing Cerebellar Damage in Neuromyelitis Optica Spectrum DisorderJ. Sun, N. Zhang, Q. Wang, X. Zhang, W. Qin, L. Yang, F.-D. Shi and C. YuAmerican Journal of Neuroradiology July 2019, 40 (7) 1156-1161; DOI: https://doi.org/10.3174/ajnr.A6098
Z
Zhang, N.
- Adult BrainOpen AccessNormal-Appearing Cerebellar Damage in Neuromyelitis Optica Spectrum DisorderJ. Sun, N. Zhang, Q. Wang, X. Zhang, W. Qin, L. Yang, F.-D. Shi and C. YuAmerican Journal of Neuroradiology July 2019, 40 (7) 1156-1161; DOI: https://doi.org/10.3174/ajnr.A6098
Zhang, X.
- Adult BrainOpen AccessNormal-Appearing Cerebellar Damage in Neuromyelitis Optica Spectrum DisorderJ. Sun, N. Zhang, Q. Wang, X. Zhang, W. Qin, L. Yang, F.-D. Shi and C. YuAmerican Journal of Neuroradiology July 2019, 40 (7) 1156-1161; DOI: https://doi.org/10.3174/ajnr.A6098
Zhang, Y.
- PediatricsYou have accessQuantitative Analysis of Punctate White Matter Lesions in Neonates Using Quantitative Susceptibility Mapping and R2* RelaxationY. Zhang, A. Rauscher, C. Kames and A.M. WeberAmerican Journal of Neuroradiology July 2019, 40 (7) 1221-1226; DOI: https://doi.org/10.3174/ajnr.A6114
Zhang, Z.
- Adult BrainOpen AccessQuantitative Delta T1 (dT1) as a Replacement for Adjudicated Central Reader Analysis of Contrast-Enhancing Tumor Burden: A Subanalysis of the American College of Radiology Imaging Network 6677/Radiation Therapy Oncology Group 0625 Multicenter Brain Tumor TrialK.M. Schmainda, M.A. Prah, Z. Zhang, B.S. Snyder, S.D. Rand, T.R. Jensen, D.P. Barboriak and J.L. BoxermanAmerican Journal of Neuroradiology July 2019, 40 (7) 1132-1139; DOI: https://doi.org/10.3174/ajnr.A6110
Zhao, H.
- Adult BrainOpen AccessAssociation of Fractional Flow on 3D-TOF-MRA with Cerebral Perfusion in Patients with MCA StenosisX. Ge, H. Zhao, Z. Zhou, X. Li, B. Sun, H. Wu, J. Wan, J. Xu, J.P. Villablanca and X. LiuAmerican Journal of Neuroradiology July 2019, 40 (7) 1124-1131; DOI: https://doi.org/10.3174/ajnr.A6095
Zhou, Z.
- Adult BrainOpen AccessAssociation of Fractional Flow on 3D-TOF-MRA with Cerebral Perfusion in Patients with MCA StenosisX. Ge, H. Zhao, Z. Zhou, X. Li, B. Sun, H. Wu, J. Wan, J. Xu, J.P. Villablanca and X. LiuAmerican Journal of Neuroradiology July 2019, 40 (7) 1124-1131; DOI: https://doi.org/10.3174/ajnr.A6095
Zuber, K.
- FELLOWS' JOURNAL CLUBAdult BrainYou have accessDiagnosis and Prediction of Relapses in Susac Syndrome: A New Use for MR Postcontrast FLAIR Leptomeningeal EnhancementS. Coulette, A. Lecler, E. Saragoussi, K. Zuber, J. Savatovsky, R. Deschamps, O. Gout, C. Sabben, J. Aboab, A. Affortit, F. Charbonneau and M. ObadiaAmerican Journal of Neuroradiology July 2019, 40 (7) 1184-1190; DOI: https://doi.org/10.3174/ajnr.A6103
From January 2011 to December 2017, nine consecutive patients with Susac syndrome and a control group of 73 patients with multiple sclerosis or clinically isolated syndrome were included. Two neuroradiologists blinded to the clinical and ophthalmologic data independently reviewed MRIs and assessed leptomeningeal enhancement and parenchymal abnormalities. Follow-up MRIs of patients with Susac syndrome were reviewed and compared with clinical and retinal fluorescein angiographic data evaluated by an independent ophthalmologist. Patients with Susac syndrome were significantly more likely to present with leptomeningeal enhancement: 5/9 (56%) versus 6/73 (8%) in the control group. They had a significantly higher leptomeningeal enhancement burden with ≥3 lesions in 5/9 patients versus 0/73. Regions of leptomeningeal enhancement were significantly more likely to be located in the posterior fossa. The authors conclude that leptomeningeal enhancement occurs frequently in Susac syndrome and could be helpful for diagnosis and prediction of clinical relapse.