Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • ASNR Foundation Special Collection
    • Most Impactful AJNR Articles
    • Photon-Counting CT
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • ASNR Foundation Special Collection
    • Most Impactful AJNR Articles
    • Photon-Counting CT
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR is seeking candidates for the AJNR Podcast Editor. Read the position description.

Review ArticleAdult Brain
Open Access

Spontaneous Intracranial Hypotension: Atypical Radiologic Appearances, Imaging Mimickers, and Clinical Look-Alikes

K.M. Bond, J.C. Benson, J.K. Cutsforth-Gregory, D.K. Kim, F.E. Diehn and C.M. Carr
American Journal of Neuroradiology August 2020, 41 (8) 1339-1347; DOI: https://doi.org/10.3174/ajnr.A6637
K.M. Bond
aFrom the Mayo Clinic School of Medicine (K.M.B.), Rochester, Minnesota
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for K.M. Bond
J.C. Benson
bDepartments of Radiology (J.C.B., D.K.K., F.E.D., C.M.C.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for J.C. Benson
J.K. Cutsforth-Gregory
cNeurology (J.K.C.-G.), Mayo Clinic, Rochester, Minnesota.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for J.K. Cutsforth-Gregory
D.K. Kim
bDepartments of Radiology (J.C.B., D.K.K., F.E.D., C.M.C.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for D.K. Kim
F.E. Diehn
bDepartments of Radiology (J.C.B., D.K.K., F.E.D., C.M.C.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for F.E. Diehn
C.M. Carr
bDepartments of Radiology (J.C.B., D.K.K., F.E.D., C.M.C.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for C.M. Carr
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. 1.↵
    1. Kranz PG,
    2. Gray L,
    3. Amrhein TJ
    . Spontaneous intracranial hypotension: 10 myths and misperceptions. Headache 2018;58:948–59 doi:10.1111/head.13328 pmid:29797515
    CrossRefPubMed
  2. 2.↵
    1. Schievink WI
    . Spontaneous spinal cerebrospinal fluid leaks and intracranial hypotension. JAMA 2006;295:2286–96 doi:10.1001/jama.295.19.2286 pmid:16705110
    CrossRefPubMedWeb of Science
  3. 3.↵
    1. Schievink WI,
    2. Meyer FB,
    3. Atkinson JL, et al
    . Spontaneous spinal cerebrospinal fluid leaks and intracranial hypotension. J Neurosurg 1996;84:598–60 doi:10.3171/jns.1996.84.4.0598 pmid:8613851
    CrossRefPubMedWeb of Science
  4. 4.↵
    1. Kranz PG,
    2. Amrhein TJ,
    3. Gray L
    . CSF venous fistulas in spontaneous intracranial hypotension: imaging characteristics on dynamic and CT myelography. AJR Am J Roentgenol 2017;209:1360–66 doi:10.2214/AJR.17.18351 pmid:29023155
    CrossRefPubMed
  5. 5.↵
    1. Schievink WI,
    2. Moser FG,
    3. Maya MM
    . CSF-venous fistula in spontaneous intracranial hypotension. Neurology 2014;83:472–73 doi:10.1212/WNL.0000000000000639 pmid:24951475
    Abstract/FREE Full Text
  6. 6.↵
    1. Kranz PG,
    2. Tanpitukpongse TP,
    3. Choudhury KR, et al
    . Imaging signs in spontaneous intracranial hypotension: prevalence and relationship to CSF pressure. AJNR Am J Neuroradiol 2016;37:1374–78 doi:10.3174/ajnr.A4689 pmid:26869465
    Abstract/FREE Full Text
  7. 7.↵
    1. Sencakova D,
    2. Mokri B,
    3. McClelland RL
    . The efficacy of epidural blood patch in spontaneous CSF leaks. Neurology 2001;57:1921–23 doi:10.1212/wnl.57.10.1921 pmid:11723293
    Abstract/FREE Full Text
  8. 8.↵
    1. Schievink WI
    . A novel technique for treatment of intractable spontaneous intracranial hypotension: lumbar dural reduction surgery. Headache 2009;49:1047–51 doi:10.1111/j.1526-4610.2009.01450.x pmid:19473279
    CrossRefPubMed
  9. 9.↵
    1. Schievink WI
    . Misdiagnosis of spontaneous intracranial hypotension. Arch Neurol 2003;60:1713–18 doi:10.1001/archneur.60.12.1713 pmid:14676045
    CrossRefPubMedWeb of Science
  10. 10.↵
    1. Kranz PG,
    2. Amrhein TJ,
    3. Schievink WI, et al
    . The “hyperdense paraspinal vein” sign: a marker of CSF-venous fistula. AJNR Am J Neuroradiol 2016;37:1379–81 doi:10.3174/ajnr.A4682 pmid:26869470
    Abstract/FREE Full Text
  11. 11.↵
    1. Mokri B,
    2. Piepgras DG,
    3. Miller GM
    . Syndrome of orthostatic headaches and diffuse pachymeningeal gadolinium enhancement. Mayo Clin Proc 1997;72:400–13 doi:10.4065/72.5.400 pmid:9146681
    CrossRefPubMedWeb of Science
  12. 12.↵
    1. Dobrocky T,
    2. Grunder L,
    3. Breiding PS, et al
    . Assessing spinal cerebrospinal fluid leaks in spontaneous intracranial hypotension with a scoring system based on brain magnetic resonance imaging findings. JAMA Neurol 2019;76:580–87 doi:10.1001/jamaneurol.2018.4921 pmid:30776059
    CrossRefPubMed
  13. 13.↵
    1. Kumar N,
    2. Cohen-Gadol AA,
    3. Wright RA, et al
    . Superficial siderosis. Neurology 2006;66:1144–52 doi:10.1212/01.wnl.0000208510.76323.5b pmid:16636229
    Abstract/FREE Full Text
  14. 14.↵
    1. Spelle L,
    2. Boulin A,
    3. Pierot L, et al
    . Spontaneous intracranial hypotension: MRI and radionuclide cisternography findings. J Neurol Neurosurg Psychiatry 1997;62:291–92 doi:10.1136/jnnp.62.3.291 pmid:9069493
    FREE Full Text
  15. 15.↵
    1. Sehgal AK,
    2. Sethi RS,
    3. Raghavan S, et al
    . Radionuclide cisternography: a prudent investigation in diagnosing spontaneous intracranial hypotension. Indian J Nucl Med 2013;28:42–44 doi:10.4103/0972-3919.116815 pmid:24019678
    CrossRefPubMed
  16. 16.↵
    1. Yoo HM,
    2. Kim SJ,
    3. Choi CG, et al
    . Detection of CSF leak in spinal CSF leak syndrome using MR myelography: correlation with radioisotope cisternography. AJNR Am J Neuroradiol 2008;29:649–54 doi:10.3174/ajnr.A0920 pmid:18202233
    Abstract/FREE Full Text
  17. 17.↵
    1. Watanabe A,
    2. Horikoshi T,
    3. Uchida M, et al
    . Diagnostic value of spinal MR imaging in spontaneous intracranial hypotension syndrome. AJNR Am J Neuroradiol 2009;30:147–51 doi:10.3174/ajnr.A1277 pmid:18768717
    Abstract/FREE Full Text
  18. 18.↵
    1. Kranz PG,
    2. Stinnett SS,
    3. Huang KT, et al
    . Spinal meningeal diverticula in spontaneous intracranial hypotension: analysis of prevalence and myelographic appearance. AJNR Am J Neuroradiol 2013;34:1284–89 doi:10.3174/ajnr.A3359 pmid:23221945
    Abstract/FREE Full Text
  19. 19.↵
    1. Meadows J,
    2. Kraut M,
    3. Guarnieri M, et al
    . Asymptomatic Chiari type I malformations identified on magnetic resonance imaging. J Neurosurg 2000;92:920–26 doi:10.3171/jns.2000.92.6.0920 pmid:10839250
    CrossRefPubMedWeb of Science
  20. 20.↵
    1. Morris Z,
    2. Whiteley WN,
    3. Longstreth WT, Jr., et al
    . Incidental findings on brain magnetic resonance imaging: systematic review and meta-analysis. BMJ 2009;339:b3016–16 doi:10.1136/bmj.b3016 pmid:19687093
    Abstract/FREE Full Text
  21. 21.↵
    1. Langridge B,
    2. Phillips E,
    3. Choi D
    . Chiari malformation type 1: a systematic review of natural history and conservative management. World Neurosurg 2017;104:213–19 doi:10.1016/j.wneu.2017.04.082 pmid:28435116
    CrossRefPubMed
  22. 22.↵
    1. Atkinson JL,
    2. Weinshenker BG,
    3. Miller GM, et al
    . Acquired Chiari I malformation secondary to spontaneous spinal cerebrospinal fluid leakage and chronic intracranial hypotension syndrome in seven cases. J Neurosurg 1998;88:237–42 doi:10.3171/jns.1998.88.2.0237 pmid:9452230
    CrossRefPubMed
  23. 23.↵
    1. Holbrook J,
    2. Saindane AM
    . Imaging of intracranial pressure disorders. Neurosurgery 2017;80:341–54 doi:10.1227/NEU.0000000000001362 pmid:27471977
    CrossRefPubMed
  24. 24.↵
    1. Sainani NI,
    2. Lawande MA,
    3. Pungavkar SA, et al
    . Spontaneous intracranial hypotension: a study of six cases with MR findings and literature review. Australas Radiol 2006;50:419–23 doi:10.1111/j.1440-1673.2006.01615.x pmid:16981936
    CrossRefPubMed
  25. 25.↵
    1. Wald JT,
    2. Diehn FE
    . Spontaneous intracranial hypotension. Applied Radiol 2018;47:18–22
  26. 26.↵
    1. Smith RM,
    2. Garza I,
    3. Robertson CE
    . Chronic CSF leak causing syringomyelia and pseudo-Arnold-Chiari malformation. Neurology 2015;85:1994 doi:10.1212/WNL.0000000000002178 pmid:26628487
    Abstract/FREE Full Text
  27. 27.↵
    1. Luxon LM,
    2. Harrison MJ
    . Chronic subdural haematoma. Q J Med 1979;48:43–53 pmid:482590
    PubMed
  28. 28.↵
    1. Schievink WI,
    2. Maya MM,
    3. Pikul BK, et al
    . Spontaneous spinal cerebrospinal fluid leaks as the cause of subdural hematomas in elderly patients on anticoagulation: report of 3 cases. J Neurosurg 2010;112:295–99 doi:10.3171/2008.10.JNS08428 pmid:19199465
    CrossRefPubMedWeb of Science
  29. 29.↵
    1. Huang YH,
    2. Yang KY,
    3. Lee TC, et al
    . Bilateral chronic subdural hematoma: what is the clinical significance? Int J Surg 2013;11:544–48 doi:10.1016/j.ijsu.2013.05.007 pmid:23707986
    CrossRefPubMed
  30. 30.↵
    1. Schievink WI,
    2. Maya MM,
    3. Moser FG, et al
    . Spectrum of subdural fluid collections in spontaneous intracranial hypotension. J Neurosurg 2005;103:608–13 doi:10.3171/jns.2005.103.4.0608 pmid:16266041
    CrossRefPubMedWeb of Science
  31. 31.↵
    1. de Noronha RJ,
    2. Sharrack B,
    3. Hadjivassiliou M, et al
    . Subdural haematoma: a potentially serious consequence of spontaneous intracranial hypotension. J Neurol Neurosurg Psychiatry 2003;74:752–55 doi:10.1136/jnnp.74.6.752 pmid:12754345
    Abstract/FREE Full Text
  32. 32.↵
    1. Chen YC,
    2. Wang YF,
    3. Li JY, et al
    . Treatment and prognosis of subdural hematoma in patients with spontaneous intracranial hypotension. Cephalalgia 2016;36:225–31 doi:10.1177/0333102415585095 pmid:25944817
    CrossRefPubMed
  33. 33.↵
    1. Rettenmaier LA,
    2. Park BJ,
    3. Holland MT, et al
    . Value of targeted epidural blood patch and management of subdural hematoma in spontaneous intracranial hypotension: case report and review of the literature. World Neurosurg 2017;97:27–38 doi:10.1016/j.wneu.2016.09.076 pmid:27693247
    CrossRefPubMed
  34. 34.↵
    1. Stone JH,
    2. Zen Y,
    3. Deshpande V
    . IgG4-related disease. N Engl J Med 2012;366:539–51 doi:10.1056/NEJMra1104650 pmid:22316447
    CrossRefPubMedWeb of Science
  35. 35.↵
    1. Lu LX,
    2. Della-Torre E,
    3. Stone JH, et al
    . IgG4-related hypertrophic pachymeningitis: clinical features, diagnostic criteria, and treatment. JAMA Neurol 2014;71:785–93 doi:10.1001/jamaneurol.2014.243 pmid:24733677
    CrossRefPubMed
  36. 36.↵
    1. Smith JK,
    2. Matheus MG,
    3. Castillo M
    . Imaging manifestations of neurosarcoidosis. AJR Am J Roentgenol 2004;182:289–95 doi:10.2214/ajr.182.2.1820289 pmid:14736648
    CrossRefPubMedWeb of Science
  37. 37.↵
    1. Pickuth D,
    2. Spielmann RP,
    3. Heywang-Köbrunner SH
    . Role of radiology in the diagnosis of neurosarcoidosis. Eur Radiol 2000;10:941–44 doi:10.1007/s003300051042 pmid:10879708
    CrossRefPubMedWeb of Science
  38. 38.↵
    1. Zajicek JP,
    2. Scolding NJ,
    3. Foster O, et al
    . Central nervous system sarcoidosis: diagnosis and management. QJM 1999;92:103–17 doi:10.1093/qjmed/92.2.103 pmid:10209662
    CrossRefPubMedWeb of Science
  39. 39.↵
    1. Otsuka M,
    2. Fujiwara T,
    3. Kuwata Y, et al
    . A case of rheumatoid pachymeningitis [in Japanese]. Rinsho Shinkeigaku 1997;37:834–40 pmid:9431000
    PubMed
  40. 40.↵
    1. Micheli F,
    2. Scorticati MC,
    3. Pikielny R, et al
    . Pachymeningeal thickening in rheumatoid arthritis. Eur Neurol 1993;33:397–98 doi:10.1159/000116980 pmid:8243519
    CrossRefPubMedWeb of Science
  41. 41.↵
    1. Marano E,
    2. D'Armiento FP,
    3. Scarano V, et al
    . Focal hypertrophic cranial pachymeningitis associated with temporal arteritis: a new case report. J Neurol 2003;250:98–100 doi:10.1007/s00415-003-0914-6 pmid:12528001
    CrossRefPubMedWeb of Science
  42. 42.↵
    1. Wen JH,
    2. Wang C,
    3. Jin YY, et al
    . Radiological and clinical findings of isolated meningeal Rosai-Dorfman disease of the central nervous system. Medicine (Baltimore) 2019;98:e15365 doi:10.1097/MD.0000000000015365 pmid:31083164
    CrossRefPubMed
  43. 43.↵
    1. Z'Graggen WJ,
    2. Sturzenegger M,
    3. Mariani L, et al
    . Isolated Rosai-Dorfman disease of intracranial meninges. Pathol Res Pract 2006;202:165–70 doi:10.1016/j.prp.2005.11.004 pmid:16377100
    CrossRefPubMed
  44. 44.↵
    1. Kumar P,
    2. Singh A,
    3. Gamanagatti S, et al
    . Imaging findings in Erdheim-Chester disease: what every radiologist needs to know. Pol J Radiol 2018;83:E54–62 doi:10.5114/pjr.2018.73290 pmid:30038679
    CrossRefPubMed
  45. 45.↵
    1. Parks NE,
    2. Goyal G,
    3. Go RS, et al
    . Neuroradiologic manifestations of Erdheim-Chester disease. Neurol Clin Pract 2018;8:15–20 doi:10.1212/CPJ.0000000000000422 pmid:29517068
    Abstract/FREE Full Text
  46. 46.↵
    1. Chin JH
    . Tuberculous meningitis: diagnostic and therapeutic challenges. Neurol Clin Pract 2014;4:199–205 doi:10.1212/CPJ.0000000000000023 pmid:25110618
    Abstract/FREE Full Text
  47. 47.↵
    1. Thurtell MJ,
    2. Keed AB,
    3. Yan M, et al
    . Tuberculous cranial pachymeningitis. Neurology 2007;68:298–300 doi:10.1212/01.wnl.0000252367.99393.34 pmid:17242338
    Abstract/FREE Full Text
  48. 48.↵
    1. Fonseka CL,
    2. Kanakkahewa TE,
    3. Singhapura S, et al
    . Tuberculous pachymeningitis presenting as a diffused dural thickening in a patient with chronic headache and recurrent neurological abnormalities for more than a decade: a case report and a review of the literature. Case Rep Infect Dis 2018;2018:3012034 doi:10.1155/2018/3012034 pmid:30364129
    CrossRefPubMed
  49. 49.↵
    1. Goyal M,
    2. Sharma A,
    3. Mishra NK, et al
    . Imaging appearance of pachymeningeal tuberculosis. AJR Am J Roentgenol 1997;169:1421–24 doi:10.2214/ajr.169.5.9353472 pmid:9353472
    CrossRefPubMed
  50. 50.↵
    1. Blazekovic A,
    2. Ozretic D,
    3. Habek M, et al
    . Neurosyphilis: the shape of a rising threat. Int J Infect Dis 2018;76:1–3 doi:10.1016/j.ijid.2018.07.022 pmid:30081207
    CrossRefPubMed
  51. 51.↵
    1. Rosa M Jr.,
    2. de Almeida Cacador T,
    3. Biasutti C, et al
    . Teaching NeuroImages: skull and dural lesions in neurosyphilis. Neurology 2016;87:e129–30 doi:10.1212/WNL.0000000000003133 pmid:27647589
    Abstract/FREE Full Text
  52. 52.↵
    1. Mekinian A,
    2. Maisonobe L,
    3. Boukari L, et al
    . Characteristics, outcome and treatments with cranial pachymeningitis: a multicenter French retrospective study of 60 patients. Medicine (Baltimore) 2018;97:e11413 doi:10.1097/MD.0000000000011413 pmid:30045263
    CrossRefPubMed
  53. 53.↵
    1. Cutsforth-Gregory JK,
    2. Sandroni P
    . Clinical neurophysiology of postural tachycardia syndrome. Handb Clin Neurol 2019;161:429–45 doi:10.1016/B978-0-444-64142-7.00066-7 pmid:31307619
    CrossRefPubMed
  54. 54.↵
    1. Graf N,
    2. Fernandes Santos AM,
    3. Ulrich CT, et al
    . Clinical symptoms and results of autonomic function testing overlap in spontaneous intracranial hypotension and postural tachycardia syndrome. Cephalalgia Reports 2018;1:251581631877377 doi:10.1177/2515816318773774
    CrossRef
  55. 55.↵
    1. Mokri B,
    2. Low PA
    . Orthostatic headaches without CSF leak in postural tachycardia syndrome. Neurology 2003;61:980–82 doi:10.1212/01.wnl.0000085868.37963.7d pmid:14557573
    Abstract/FREE Full Text
  56. 56.↵
    1. Raj SR
    . The postural tachycardia syndrome (POTS): pathophysiology, diagnosis and management. Indian Pacing Electrophysiol J 2006;6:84–99 pmid:16943900
    PubMed
  57. 57.↵
    1. Bleasdale-Barr KM,
    2. Mathias CJ
    . Neck and other muscle pains in autonomic failure: their association with orthostatic hypotension. J R Soc Med 1998;91:355–59 doi:10.1177/014107689809100704 pmid:9771493
    CrossRefPubMedWeb of Science
  58. 58.↵
    1. Naschitz JE,
    2. Rosner I
    . Orthostatic hypotension: framework of the syndrome. Postgrad Med J 2007;83:568–74 doi:10.1136/pgmj.2007.058198 pmid:17823222
    Abstract/FREE Full Text
  59. 59.↵
    Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition. Cephalalgia 2018; 38:1–211 doi:10.1177/0333102417738202 pmid:29368949
    CrossRefPubMed
  60. 60.↵
    1. Furman JM,
    2. Marcus DA,
    3. Balaban CD
    . Vestibular migraine: clinical aspects and pathophysiology. Lancet Neurol 2013;12:706–15 doi:10.1016/S1474-4422(13)70107-8 pmid:23769597
    CrossRefPubMedWeb of Science
  61. 61.↵
    1. Montenegro MM,
    2. Cutsforth-Gregory JK
    . Orthostatic headache after suboccipital craniectomy without CSF leak: two case reports. Headache 2018;58:1238–43 doi:10.1111/head.13346 pmid:29920678
    CrossRefPubMed
  62. 62.↵
    1. Schievink WI,
    2. Maya MM
    . Cerebral venous thrombosis in spontaneous intracranial hypotension. Headache 2008;48:1511–19 doi:10.1111/j.1526-4610.2008.01251.x pmid:19076649
    CrossRefPubMedWeb of Science
  63. 63.↵
    1. Stam J
    . Thrombosis of the cerebral veins and sinuses. N Engl J Med 2005;352:1791–98 doi:10.1056/NEJMra042354 pmid:15858188
    CrossRefPubMedWeb of Science
  64. 64.↵
    1. Zhang D,
    2. Wang J,
    3. Zhang Q, et al
    . Cerebral venous thrombosis in spontaneous intracranial hypotension: a report on 4 cases and a review of the literature. Headache 2018;58:1244–55 doi:10.1111/head.13413 pmid:30238694
    CrossRefPubMed
  65. 65.↵
    1. Kataoka H,
    2. Tanizawa E,
    3. Ueno S
    . Spontaneous intracranial hypotension is associated with a risk of venous sinus thrombosis and subdural hematoma. Cerebrovasc Dis 2007;23:315–17 doi:10.1159/000098446 pmid:17213717
    CrossRefPubMed
  66. 66.↵
    1. Mokri B
    . The Monro-Kellie hypothesis: applications in CSF volume depletion. Neurology 2001;56:1746–48 doi:10.1212/wnl.56.12.1746 pmid:11425944
    Abstract/FREE Full Text
  67. 67.↵
    1. Rice CM,
    2. Renowden SA,
    3. Sandeman DR, et al
    . Spontaneous intracranial hypotension and venous sinus thrombosis. Pract Neurol 2013;13:120–24 doi:10.1136/practneurol-2012-000257 pmid:23468563
    FREE Full Text
  68. 68.↵
    1. Yoon KW,
    2. Cho MK,
    3. Kim YJ, et al
    . Sinus thrombosis in a patient with intracranial hypotension: a suggested hypothesis of venous stasis. A case report. Interv Neuroradiol 2011;17:248–51 doi:10.1177/159101991101700218 pmid:21696667
    CrossRefPubMed
  69. 69.↵
    1. Costa P,
    2. Del Zotto E,
    3. Giossi A, et al
    . Headache due to spontaneous intracranial hypotension and subsequent cerebral vein thrombosis. Headache 2012;52:1592–96 doi:10.1111/j.1526-4610.2012.02261.x pmid:23046074
    CrossRefPubMed
  70. 70.↵
    1. Savoiardo M,
    2. Armenise S,
    3. Spagnolo P, et al
    . Dural sinus thrombosis in spontaneous intracranial hypotension: hypotheses on possible mechanisms. J Neurol 2006;253:1197–1202 doi:10.1007/s00415-006-0194-z pmid:16680559
    CrossRefPubMedWeb of Science
  71. 71.↵
    1. Richard S,
    2. Kremer S,
    3. Lacour JC, et al
    . Cerebral venous thrombosis caused by spontaneous intracranial hypotension: two cases. Eur J Neurol 2007;14:1296–98 doi:10.1111/j.1468-1331.2007.01947.x pmid:17868278
    CrossRefPubMed
  72. 72.↵
    1. Berroir S,
    2. Grabli D,
    3. Heran F, et al
    . Cerebral sinus venous thrombosis in two patients with spontaneous intracranial hypotension. Cerebrovasc Dis 2004;17:9–12 doi:10.1159/000073892 pmid:14530632
    CrossRefPubMedWeb of Science
  73. 73.↵
    1. Neary D,
    2. Snowden JS,
    3. Gustafson L, et al
    . Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. Neurology 1998;51:1546–54 doi:10.1212/wnl.51.6.1546 pmid:9855500
    Abstract/FREE Full Text
  74. 74.↵
    1. Neary D,
    2. Snowden JS,
    3. Northen B, et al
    . Dementia of frontal lobe type. J Neurol Neurosurg Psychiatry 1988;51:353–61 doi:10.1136/jnnp.51.3.353 pmid:3258902
    Abstract/FREE Full Text
  75. 75.↵
    1. Hong M,
    2. Shah GV,
    3. Adams KM, et al
    . Spontaneous intracranial hypotension causing reversible frontotemporal dementia. Neurology 2002;58:1285–87 doi:10.1212/wnl.58.8.1285 pmid:11971102
    Abstract/FREE Full Text
  76. 76.↵
    1. Mostofi E,
    2. Schievink WI,
    3. Sim VL
    . Dural reduction surgery: a treatment option for frontotemporal brain sagging syndrome. Can J Neurol Sci 2016;43:593–95 doi:10.1017/cjn.2016.3 pmid:26972054
    CrossRefPubMed
  77. 77.↵
    1. Wicklund MR,
    2. Mokri B,
    3. Drubach DA, et al
    . Frontotemporal brain sagging syndrome: an SIH-like presentation mimicking FTD. Neurology 2011;76:1377–82 doi:10.1212/WNL.0b013e3182166e42 pmid:21502595
    Abstract/FREE Full Text
  78. 78.↵
    1. Schievink WI,
    2. Maya MM,
    3. Barnard ZR, et al
    . Behavioral variant frontotemporal dementia as a serious complication of spontaneous intracranial hypotension. Oper Neurosurg (Hagerstown) 2018;15:505–15 doi:10.1093/ons/opy029 pmid:29534203
    CrossRefPubMed
  79. 79.↵
    1. Firat AK,
    2. Karakas HM,
    3. Firat Y, et al
    . Spontaneous intracranial hypotension with pituitary adenoma. J Headache Pain 2006;7:47–50 doi:10.1007/s10194-006-0269-3 pmid:16485075
    CrossRefPubMed
  80. 80.↵
    1. Tapia DQ,
    2. Pardo J,
    3. Serrano JM, et al
    . Spontaneous intracranial hypotension: use of unenhanced MRI. Neuroradiology 2000;42:529–31 doi:10.1007/s002340000327 pmid:10952188
    CrossRefPubMed
  81. 81.↵
    1. Tsui EY,
    2. Ng SH,
    3. Cheung YK, et al
    . Spontaneous intracranial hypotension with diffuse dural enhancement of the spinal canal and transient enlargement of the pituitary gland. Eur J Radiol 2001;38:59–63 doi:10.1016/s0720-048x(01)00288-1 pmid:11287167
    CrossRefPubMed
  82. 82.↵
    1. Leung GK,
    2. Ho J,
    3. Pu JK
    . Pituitary enlargement in spontaneous intracranial hypotension: a diagnostic pitfall. Acta Neurochir (Wien) 2011;153:2445–46 doi:10.1007/s00701-011-1099-x pmid:21800104
    CrossRefPubMed
  83. 83.↵
    1. Luna J,
    2. Khanna I,
    3. Cook FJ, et al
    . Sagging brain masquerading as a pituitary adenoma. J Clin Endocrinol Metab 2014;99:3043–43 doi:10.1210/jc.2014-1397 pmid:24947035
    CrossRefPubMed
  84. 84.↵
    1. Fearnley JM,
    2. Stevens JM,
    3. Rudge P
    . Superficial siderosis of the central nervous system. Brain 1995;118(Pt 4):1051–66 doi:10.1093/brain/118.4.1051 pmid:7655881
    CrossRefPubMedWeb of Science
  85. 85.↵
    1. Levy M,
    2. Turtzo C,
    3. Llinas RH
    . Superficial siderosis: a case report and review of the literature. Nat Clin Pract Neurol 2007;3:54–58 doi:10.1038/ncpneuro0356 pmid:17205075
    CrossRefPubMedWeb of Science
  86. 86.↵
    1. Linn J,
    2. Herms J,
    3. Dichgans M, et al
    . Subarachnoid hemosiderosis and superficial cortical hemosiderosis in cerebral amyloid angiopathy. AJNR Am J Neuroradiol 2008;29:184–86 doi:10.3174/ajnr.A0783 pmid:17947366
    Abstract/FREE Full Text
  87. 87.↵
    1. Beck J,
    2. Häni L,
    3. Ulrich CT, et al
    . Diagnostic challenges and therapeutic possibilities in spontaneous intracranial hypotension. Clinical and Translational Neuroscience 2018;2:2514183X1878737 doi:10.1177/2514183X18787371
    CrossRef
  88. 88.↵
    1. Webb AJ,
    2. Flossmann E,
    3. Armstrong RJ
    . Superficial siderosis following spontaneous intracranial hypotension. Pract Neurol 2015;15:382–84 doi:10.1136/practneurol-2015-001169 pmid:26139598
    FREE Full Text
  89. 89.↵
    1. Schievink WI,
    2. Maya MM
    . Spinal meningeal diverticula, spontaneous intracranial hypotension, and superficial siderosis. Neurology 2017;88:916–17 doi:10.1212/WNL.0000000000003665 pmid:28130464
    Abstract/FREE Full Text
  90. 90.↵
    1. Kumar N
    . Neuroimaging in superficial siderosis: an in-depth look. AJNR Am J Neuroradiol 2010;31:5–14 doi:10.3174/ajnr.A1628 pmid:19729538
    Abstract/FREE Full Text
  91. 91.↵
    1. Kumar N,
    2. Lane JI,
    3. Piepgras DG
    . Superficial siderosis: sealing the defect. Neurology 2009;72:671–73 doi:10.1212/01.wnl.0000342457.22536.af pmid:19221303
    FREE Full Text
  92. 92.↵
    1. Kumar N,
    2. McKeon A,
    3. Rabinstein AA, et al
    . Superficial siderosis and CSF hypovolemia: the defect (dural) in the link. Neurology 2007;69:925–26 doi:10.1212/01.wnl.0000267847.69896.be pmid:17724297
    FREE Full Text
  93. 93.↵
    1. Schievink WI,
    2. Wasserstein P,
    3. Maya MM
    . Intraspinal hemorrhage in spontaneous intracranial hypotension: link to superficial siderosis? Report of 2 cases. J Neurosurg Spine 2016;24:454–56 doi:10.3171/2015.6.SPINE15428 pmid:26588500
    CrossRefPubMed
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 41 (8)
American Journal of Neuroradiology
Vol. 41, Issue 8
1 Aug 2020
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Spontaneous Intracranial Hypotension: Atypical Radiologic Appearances, Imaging Mimickers, and Clinical Look-Alikes
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
K.M. Bond, J.C. Benson, J.K. Cutsforth-Gregory, D.K. Kim, F.E. Diehn, C.M. Carr
Spontaneous Intracranial Hypotension: Atypical Radiologic Appearances, Imaging Mimickers, and Clinical Look-Alikes
American Journal of Neuroradiology Aug 2020, 41 (8) 1339-1347; DOI: 10.3174/ajnr.A6637

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Spontaneous Intracranial Hypotension: Atypical Radiologic Appearances, Imaging Mimickers, and Clinical Look-Alikes
K.M. Bond, J.C. Benson, J.K. Cutsforth-Gregory, D.K. Kim, F.E. Diehn, C.M. Carr
American Journal of Neuroradiology Aug 2020, 41 (8) 1339-1347; DOI: 10.3174/ajnr.A6637
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • CONCLUSIONS
    • Acknowledgments
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Spinal CSF Leaks: The Neuroradiologist Transforming Care
  • Skull Base CSF Leaks: Potential Underlying Pathophysiology and Evaluation of Brain MR Imaging Findings Associated with Spontaneous Intracranial Hypotension
  • Natural history of spontaneous intracranial hypotension: a clinical and imaging study
  • Likelihood of Discovering a CSF Leak Based on Intracranial MRI Findings in Patients without a Spinal Longitudinal Extradural Collection: A New Probabilistic Scoring System
  • The Monro-Kellie Doctrine: A Review and Call for Revision
  • Case of spontaneous intracranial hypotension: clinical, neuroimaging and treatment approach
  • Crossref (29)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Spontaneous intracranial hypotension: searching for the CSF leak
    Tomas Dobrocky, Patrick Nicholson, Levin Häni, Pasquale Mordasini, Timo Krings, Waleed Brinjikji, Jeremy K Cutsforth-Gregory, Ralph Schär, Christoph Schankin, Jan Gralla, Vitor M Pereira, Andreas Raabe, Richard Farb, Jürgen Beck, Eike I Piechowiak
    The Lancet Neurology 2022 21 4
  • International Consensus Statement: Spontaneous Cerebrospinal Fluid Rhinorrhea
    Christos Georgalas, Amanda Oostra, Shahzada Ahmed, Paolo Castelnuovo, Iacopo Dallan, Wouter van Furth, Richard J. Harvey, Philippe Herman, Dimitrios Kombogiorgas, Davide Locatelli, Cem Meco, Jim N. Palmer, Otavio Piltcher, Anshul M. Sama, Hesham Saleh, Raj Sindwani, Thibaut Van Zele, Bradford A. Woodworth
    International Forum of Allergy & Rhinology 2021 11 4
  • The Monro-Kellie Doctrine: A Review and Call for Revision
    J.C. Benson, A.A. Madhavan, J.K. Cutsforth-Gregory, D.R. Johnson, C.M. Carr
    American Journal of Neuroradiology 2023 44 1
  • Skull Base CSF Leaks: Potential Underlying Pathophysiology and Evaluation of Brain MR Imaging Findings Associated with Spontaneous Intracranial Hypotension
    Ian T. Mark, Jeremy Cutsforth-Gregory, Patrick Luetmer, Ajay A. Madhavan, Michael Oien, Paul Farnsworth, Girish Bathla, Steve Messina, Michael Link, Jamie Van Gompel
    American Journal of Neuroradiology 2024 45 10
  • ACR Appropriateness Criteria® Headache: 2022 Update
    Pallavi S. Utukuri, Robert Y. Shih, Amna A. Ajam, Kathryn E. Callahan, Doris Chen, Jeffrey W. Dunkle, Christopher H. Hunt, Jana Ivanidze, Luke N. Ledbetter, Ryan K. Lee, Omojo Malu, Jeffrey S. Pannell, Jeffrey M. Pollock, Sonja X. Potrebic, Michael Setzen, Richard D. Shih, Bruno P. Soares, Michael D. Staudt, Lily L. Wang, Judah Burns
    Journal of the American College of Radiology 2023 20 5
  • Cerebrospinal Fluid Leaks, Spontaneous Intracranial Hypotension, and Chiari I Malformation
    Rahul Kumar, Jeremy K. Cutsforth-Gregory, Waleed Brinjikji
    Neurosurgery Clinics of North America 2023 34 1
  • Likelihood of Discovering a CSF Leak Based on Intracranial MRI Findings in Patients without a Spinal Longitudinal Extradural Collection: A New Probabilistic Scoring System
    John C. Benson, Ajay A. Madhavan, Ian T. Mark, Jeremy K. Cutsforth-Gregory, Waleed Brinjikji, Jared T. Verdoorn
    American Journal of Neuroradiology 2023 44 11
  • Natural history of spontaneous intracranial hypotension: a clinical and imaging study
    James Williams, Waleed Brinjikji, Jeremy K Cutsforth-Gregory
    Journal of NeuroInterventional Surgery 2023 15 11
  • Outcome of epidural blood patch for imaging-negative spontaneous intracranial hypotension
    So Youn Choi, Minjung Seong, Eung Yeop Kim, Michelle Sojung Youn, Soohyun Cho, Hyemin Jang, Mi Ji Lee
    Cephalalgia 2023 43 2
  • Spontaneous Intracranial Hypotension - A Dilemma
    Dhaval Shukla, Nishanth Sadashiva, Jitender Saini, Sriganesh Kamath
    Neurology India 2021 69 Suppl 2

More in this TOC Section

  • Diagnostic Neuroradiology of Monoclonal Antibodies
  • Clinical Outcomes After Chiari I Decompression
  • Segmentation of Brain Metastases with BLAST
Show more Adult Brain

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

Special Collections

  • AJNR Awards
  • ASNR Foundation Special Collection
  • Most Impactful AJNR Articles
  • Photon-Counting CT
  • Spinal CSF Leak Articles (Jan 2020-June 2024)

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire