Research ArticleAdult Brain
Open Access
MRI-Based Deep-Learning Method for Determining Glioma MGMT Promoter Methylation Status
C.G.B. Yogananda, B.R. Shah, S.S. Nalawade, G.K. Murugesan, F.F. Yu, M.C. Pinho, B.C. Wagner, B. Mickey, T.R. Patel, B. Fei, A.J. Madhuranthakam and J.A. Maldjian
American Journal of Neuroradiology May 2021, 42 (5) 845-852; DOI: https://doi.org/10.3174/ajnr.A7029
C.G.B. Yogananda
aFrom the Advanced Neuroscience Imaging Research Lab (C.G.B.Y., B.R.S., S.S.N., G.K.M., F.F.Y., M.C.P., B.C.W., A.J.M., J.A.M.), Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas
B.R. Shah
aFrom the Advanced Neuroscience Imaging Research Lab (C.G.B.Y., B.R.S., S.S.N., G.K.M., F.F.Y., M.C.P., B.C.W., A.J.M., J.A.M.), Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas
S.S. Nalawade
aFrom the Advanced Neuroscience Imaging Research Lab (C.G.B.Y., B.R.S., S.S.N., G.K.M., F.F.Y., M.C.P., B.C.W., A.J.M., J.A.M.), Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas
G.K. Murugesan
aFrom the Advanced Neuroscience Imaging Research Lab (C.G.B.Y., B.R.S., S.S.N., G.K.M., F.F.Y., M.C.P., B.C.W., A.J.M., J.A.M.), Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas
F.F. Yu
aFrom the Advanced Neuroscience Imaging Research Lab (C.G.B.Y., B.R.S., S.S.N., G.K.M., F.F.Y., M.C.P., B.C.W., A.J.M., J.A.M.), Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas
M.C. Pinho
aFrom the Advanced Neuroscience Imaging Research Lab (C.G.B.Y., B.R.S., S.S.N., G.K.M., F.F.Y., M.C.P., B.C.W., A.J.M., J.A.M.), Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas
B.C. Wagner
aFrom the Advanced Neuroscience Imaging Research Lab (C.G.B.Y., B.R.S., S.S.N., G.K.M., F.F.Y., M.C.P., B.C.W., A.J.M., J.A.M.), Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas
B. Mickey
bDepartment of Neurological Surgery (B.M., T.R.P.), University of Texas Southwestern Medical Center, Dallas, Texas
T.R. Patel
bDepartment of Neurological Surgery (B.M., T.R.P.), University of Texas Southwestern Medical Center, Dallas, Texas
B. Fei
cDepartment of Bioengineering (B.F.), University of Texas at Dallas, Richardson, Texas
A.J. Madhuranthakam
aFrom the Advanced Neuroscience Imaging Research Lab (C.G.B.Y., B.R.S., S.S.N., G.K.M., F.F.Y., M.C.P., B.C.W., A.J.M., J.A.M.), Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas
J.A. Maldjian
aFrom the Advanced Neuroscience Imaging Research Lab (C.G.B.Y., B.R.S., S.S.N., G.K.M., F.F.Y., M.C.P., B.C.W., A.J.M., J.A.M.), Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas

Article Information
vol. 42 no. 5 845-852
PubMed
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History
- Received June 24, 2020
- Accepted after revision November 21, 2020
- Published online May 12, 2021.
Article Versions
- Latest version (March 4, 2021 - 08:56).
- You are viewing the most recent version of this article.
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© 2021 by American Journal of Neuroradiology Indicates open access to non-subscribers at www.ajnr.org
Author Information
- C.G.B. Yoganandaa,
- B.R. Shaha,
- S.S. Nalawadea,
- G.K. Murugesana,
- F.F. Yua,
- M.C. Pinhoa,
- B.C. Wagnera,
- B. Mickeyb,
- T.R. Patelb,
- B. Feic,
- A.J. Madhuranthakama and
- J.A. Maldjiana
- aFrom the Advanced Neuroscience Imaging Research Lab (C.G.B.Y., B.R.S., S.S.N., G.K.M., F.F.Y., M.C.P., B.C.W., A.J.M., J.A.M.), Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas
- bDepartment of Neurological Surgery (B.M., T.R.P.), University of Texas Southwestern Medical Center, Dallas, Texas
- cDepartment of Bioengineering (B.F.), University of Texas at Dallas, Richardson, Texas
- Please address correspondence to Joseph A. Maldjian, MD, Department of Radiology, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-9178; e-mail: joseph.maldjian{at}utsouthwestern.edu
Funding
NIH/NCI
U01CA207091
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C.G.B. Yogananda, B.R. Shah, S.S. Nalawade, G.K. Murugesan, F.F. Yu, M.C. Pinho, B.C. Wagner, B. Mickey, T.R. Patel, B. Fei, A.J. Madhuranthakam, J.A. Maldjian
MRI-Based Deep-Learning Method for Determining Glioma MGMT Promoter Methylation Status
American Journal of Neuroradiology May 2021, 42 (5) 845-852; DOI: 10.3174/ajnr.A7029
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MRI-Based Deep-Learning Method for Determining Glioma MGMT Promoter Methylation Status
C.G.B. Yogananda, B.R. Shah, S.S. Nalawade, G.K. Murugesan, F.F. Yu, M.C. Pinho, B.C. Wagner, B. Mickey, T.R. Patel, B. Fei, A.J. Madhuranthakam, J.A. Maldjian
American Journal of Neuroradiology May 2021, 42 (5) 845-852; DOI: 10.3174/ajnr.A7029
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