Research ArticleBRAIN
Age-Related Total Gray Matter and White Matter Changes in Normal Adult Brain. Part II: Quantitative Magnetization Transfer Ratio Histogram Analysis
Yulin Ge, Robert I. Grossman, James S. Babb, Marcie L. Rabin, Lois J. Mannon and Dennis L. Kolson
American Journal of Neuroradiology September 2002, 23 (8) 1334-1341;
Yulin Ge
Robert I. Grossman
James S. Babb
Marcie L. Rabin
Lois J. Mannon

References
- ↵Reiss AL, Abrams MT, Singer HS, Ross JL, Denckla MB. Brain development, gender and IQ in children: a volumetric imaging study. Brain 1996;119:1763–1774
- ↵Giedd JN, Snell JW, Lange N, et al. Quantitative magnetic resonance imaging of human brain development: ages 4–18. Cereb Cortex 1996;6:551–560
- ↵Coffey CE, Wilkinson WE, Parashos IA, et al. Quantitative cerebral anatomy of the aging human brain: a cross-sectional study using magnetic resonance imaging. Neurology 1992;42:527–536
- Murphy DGM, DeCarli C, Schapiro MB, Rapoport SI, Horwitz B. Age-related differences in volumes of subcortical nuclei, brain matter, and cerebrospinal fluid in healthy men as measured with magnetic resonance imaging. Arch Neurol 1992;49:839–845
- Kikinis R, Shenton ME, Gerig G, et al. Routine quantitative analysis of brain and cerebrospinal fluid spaces with MR imaging. J Magn Reson Imaging 1992;2:619–629
- ↵Filipek PA, Richelme C, Kenndy DN, Caviness VS Jr. The young adult human brain: an MRI-based morphometric analysis. Cereb Cortex 1994;4:344–360
- ↵Salonen O, Autti T, Raininko R, Ylikoski A, Erkinjuntti T. MRI of the brain in neurologically healthy middle-aged and elderly individuals. Neuroradiology 1997;39:537–545
- ↵Jack CR Jr., Petersen RC, Xu Y, et al. Rate of medial temporal lobe atrophy in typical aging and Alzheimer’s disease. Neurology 1998;51:993–999
- ↵Barber R, Scheltens P, Gholkar A, et al. White matter lesions on magnetic resonance imaging in dementia with Lewy bodies, Alzheimer’s disease, vascular dementia, and normal aging. J Neurol Neurosurg Psychiatry 1999;67:66–72
- ↵Loevner LA, Grossman RI, Cohen JA, Lexa FJ, Kessler D, Kolson DL. Microscopic disease in normal-appearing white matter on conventional MR images in patients with multiple sclerosis: assessment with magnetization-transfer measurements. Radiology 1995;196:511–515
- Prager JM, Rosenblum JD, Huddle DC, Diamond CK, Metz CE. The magnetization transfer effect in cerebral infarction. AJNR Am J Neuroradiol 1994;15:1497–1500
- ↵Kasner SE, Galetta SL, McGowan JC, Grossman RI. Magnetization transfer imaging in progressive multifocal leukoencephalopathy. Neurology 1997;48:534–536
- ↵Boorstein JM, Wong KT, Grossman RI, Bolinger L, McGowan JC. Metastatic lesions of the brain: imaging with magnetization transfer. Radiology 1994;191:799–803
- ↵Wong KT, Grossman RI, Boorstein JM, Lexa FJ, McGowan JC. Magnetization transfer imaging of periventricular hyperintense white matter in the elderly. AJNR Am J Neuroradiol 1995;16:253–258
- ↵van Buchem MA, McGowan JC, Kolson DL, Polsansky M, Grossman RI. Quantitative volumetric magnetization transfer analysis in multiple sclerosis: estimation of macroscopic and microscopic disease burden. Magn Reson Med 1996;36:632–636
- ↵Phillips MD, Grossman RI, Miki Y, et al. Comparison of T2 lesion volume on magnetization transfer ratio histogram analysis and of lesion burden in patients with multiple sclerosis. AJNR Am J Neuroradiol 1998;19:1055–1060
- ↵Ge Y, Grossman RI, Babb JS, Rabin ML, Mannon LJ, Kolson DL. Age-related gray matter and white matter changes with aging in healthy adults, I: Quantitative volumetric MR imaging analysis. AJNR. •••.
- ↵Forsen S, Hoffman RA. Study of moderately rapid chemical exchange reactions by means of nuclear magnetic double resonance. J Chem Phys 1964;39:2892–2901
- ↵Wolff SD, Balaban RS. Magnetization transfer imaging: practical aspects and clinical applications. Radiology 1994;192:593–599
- ↵Engelbrecht V, Rassek M, Presis S, Wald C, Modder U. Age-dependent changes in magnetization transfer contrast of white matter in the pediatric brain. AJNR Am J Neuroradiol 1998;19:1923–1929
- ↵Dobbing J, Sands J. Quantitative growth and development of human brain. Arch Dis Child 1973;48:757–767
- ↵Kinney HC, Karthigasan J, Borenshteyn NI, Flax JD, Kirschner DA. Myelination in the developing human brain: biochemical correlates. Neurochem Res 1994;19:983–996
- ↵Hofman PA, Kemerink GJ, Jolles J, Wilmink JT. Quantitative analysis of magnetization transfer images of the brain: effect of closed head injury, age and sex on white matter. Magn Reson Med 1999;42:803–806
- ↵Tanabe JL, Ezekiel F, Jagust WJ, et al. Magnetization transfer ratio of white matter hyperintensities in subcortical ischemic vascular dementia. AJNR Am J Neuroradiol 1999;20:839–844
- ↵Pfefferbaum A, Sullivan EV, Heduhus M, Lim KO, Adalsteinsson EA, Moseley M. Age-related decline in brain white matter anisotropy measured with spatially corrected echo-planar diffusion tensor imaging. Magn Reson Med 2000;44:259–268
- ↵Mehta RC, Pike GB, Enzman DR. Magnetization transfer MR of the normal adult brain. AJNR Am J Neuroradiol 1995;16:2085–2091
- ↵Finelli DA. Magnetization transfer in neuroimaging. Magn Reson Imaging Clin North Am 1998;6:31–52
- ↵
- ↵Melhem ER, Benson ML, Beauchamp NJ, Lee RR. Cervical spondylosis: three-dimensional gradient-echo MR with magnetization transfer. AJNR Am J Neuroradiol 1996;17:705–711
- ↵Rovaris M, Viti B, Ciboddo G, et al. Brain involvement in systemic immune mediated diseases: magnetic resonance and magnetisation transfer imaging study. J Neurol Neurosurg Psychiatry 2000;68:170–177
- ↵Filippi M. Magnetization transfer imaging to monitor the evolution of individual multiple sclerosis lesions. Neurology 1999;53:S18–S22
- ↵Ge Y, Grossman RI, Udupa JK, Babb JS, Kolson DL, McGowan JC. Magnetization transfer ratio histogram analysis of gray matter in relapsing-remitting multiple sclerosis. AJNR Am J Neuroradiol 2001;22:470–475
- ↵Alavi A, Newberg AB, Souder E, Berlin JA. Quantitative analysis of PET and MRI data in normal aging and Alzheimer’s disease: atrophy weighted total brain metabolism and absolute whole brain metabolism as reliable discriminators. J Nucl Med 1993;34:1681–1687
- ↵Lundbom N. Determination of magnetization transfer contrast in tissue: an MR imaging study of brain tumors. AJR Am J Roentgenol 1992;159:1279–1285
- ↵Ge Y, Grossman RI, Udupa JK, Babb JS, Mannon LJ, McGowan JC. Magnetization transfer ratio histogram analysis of normal-appearing gray matter and normal-appearing white matter in multiple sclerosis. J Comput Assist Tomogr 2002;26:62–68
- ↵Yakovlev PI, Lecours AR. The myelogenetic cycles of regional maturation of the brain. In: Minkrowski A, ed. Regional Development of the Brain in Early Life. Oxford, England: Blackwell;1967 :3–70
- ↵Courchesne E, Chisum HJ, Townsend J, et al. Normal brain development and aging: quantitative analysis at in vivo MR imaging in healthy volunteers. Radiology 2000;216:672–682
- Breger RK, Yetkin FZ, Fischer ME, Papke RA, Haughton VM, Rimm AA. T1 and T2 in the cerebrum: correlation with age, gender and demographic factors. Radiology 1991;181:545–547
- ↵Sullivan EV, Adalsteinsson E, Hedehus M, et al. Equivalent disruption of regional white matter microstructure in ageing healthy men and women. Neuroreport 2001;12:99–104
In this issue
Advertisement
Yulin Ge, Robert I. Grossman, James S. Babb, Marcie L. Rabin, Lois J. Mannon, Dennis L. Kolson
Age-Related Total Gray Matter and White Matter Changes in Normal Adult Brain. Part II: Quantitative Magnetization Transfer Ratio Histogram Analysis
American Journal of Neuroradiology Sep 2002, 23 (8) 1334-1341;
0 Responses
Age-Related Total Gray Matter and White Matter Changes in Normal Adult Brain. Part II: Quantitative Magnetization Transfer Ratio Histogram Analysis
Yulin Ge, Robert I. Grossman, James S. Babb, Marcie L. Rabin, Lois J. Mannon, Dennis L. Kolson
American Journal of Neuroradiology Sep 2002, 23 (8) 1334-1341;
Jump to section
Related Articles
- No related articles found.
Cited By...
- Anatomical characterization of the inferior petrosal sinus and adjacent cerebellopontine angle cistern for development of an endovascular transdural cerebrospinal fluid shunt
- Proximal nerve magnetization transfer MRI relates to disability in Charcot-Marie-Tooth diseases
- Magnetization Transfer Imaging in Premanifest and Manifest Huntington Disease: A 2-Year Follow-Up
- Aortic Pulse Wave Velocity Predicts Focal White Matter Hyperintensities in a Biracial Cohort of Older Adults
- Mapping Infant Brain Myelination with Magnetic Resonance Imaging
- The Impact of Sex and Vascular Risk Factors on Brain Tissue Changes with Aging: Magnetization Transfer Imaging Results of the Austrian Stroke Prevention Study
- Magnetization Transfer Imaging Shows Tissue Abnormalities in the Reversible Penumbra
- Diffusion tensor magnetic resonance imaging at 3.0 tesla shows subtle cerebral grey matter abnormalities in patients with migraine
- Influence of aging on brain gray and white matter changes assessed by conventional, MT, and DT MRI
- Fatigue and primary biliary cirrhosis: association of globus pallidus magnetisation transfer ratio measurements with fatigue severity and blood manganese levels
- Magnetization transfer and diffusion tensor MRI show gray matter damage in neuromyelitis optica
This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.
More in this TOC Section
Similar Articles
Advertisement