Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • ASNR Foundation Special Collection
    • Most Impactful AJNR Articles
    • Photon-Counting CT
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • ASNR Foundation Special Collection
    • Most Impactful AJNR Articles
    • Photon-Counting CT
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR is seeking candidates for the AJNR Podcast Editor. Read the position description.

Research ArticleBRAIN

Combination of Single-Voxel Proton MR Spectroscopy and Apparent Diffusion Coefficient Calculation in the Evaluation of Common Brain Tumors

Nail Bulakbasi, Murat Kocaoglu, Fatih Örs, Cem Tayfun and Taner Üçöz
American Journal of Neuroradiology February 2003, 24 (2) 225-233;
Nail Bulakbasi
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Murat Kocaoglu
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Fatih Örs
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Cem Tayfun
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Taner Üçöz
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. ↵
    Bruhn H, Frahm J, Gyngell ML, et al. Noninvasive differentiation of tumors with use of localized H-1 MR spectroscopy in vivo: initial experience in patients with cerebral tumors. Radiology 1989;172:541–548
    PubMedWeb of Science
  2. ↵
    Segebarth CM, Baleriaux DF, Luyten PR, den Hollander JA. Detection of metabolic heterogeneity of human intracranial tumors in vivo by H-1 NMR spectroscopic imaging. Magn Reson Med 1990;13:62–76
    PubMedWeb of Science
  3. ↵
    Fulham MJ, Bizzi A, Dietz MJ, et al. Mapping of brain tumor metabolites with proton MR spectroscopic imaging: clinical relevance. Radiology 1992;185:675–686
    PubMed
  4. Baker PB, Glickson JD, Brayn RN. In vivo magnetic resonance spectroscopy of human brain tumors. Top Magn Reson Imaging 1993;5:32–45
    PubMed
  5. ↵
    Poptani H, Gupta RK, Roy R, Pandey R, Jain VK, Chhabra DK. Characterization of intracranial mass lesions with in vivo proton MR spectroscopy. AJNR Am J Neuroradiol 1995;16:1593–1603
    Abstract
  6. ↵
    Castillo M, Kwock L, Mukherji SK. Clinical applications of MR spectroscopy. AJNR Am J Neuroradiol 1996;17:1–15
    PubMedWeb of Science
  7. Krouwer HGJ, Kim TA, Rand SD, et al. Single-voxel proton MR spectroscopy of nonneoplastic brain lesions suggestive of a neoplasm. AJNR Am J Neuroradiol 1998;19:1695–1703
    Abstract
  8. ↵
    Castillo M, Kwock L. Proton MR spectroscopy of common brain tumors. Neuroimaging Clin North Am 1998;8:733–752
  9. ↵
    Meyerand ME, Pipas JM, Mamourian A, Tosteson TD, Dunn JF. Classification of biopsy-confirmed brain tumors using single-voxel MR spectroscopy. AJNR Am J Neuroradiol 1999;20:117–123
    Abstract/FREE Full Text
  10. Nelson SJ, Vigneron DB, Dillon WP. Serial evaluation of patients with brain tumors using volume MRI and 3D 1-H MRSI. NMR Biomed 1999;12:123–128
    CrossRefPubMed
  11. ↵
    Castillo M, Kwock L. Clinical applications of proton magnetic resonance spectroscopy in the evaluation of common intracranial tumors. Top Magn Reson Imaging 1999;10:104–113
    PubMed
  12. Grand S, Passaro G, Ziegler A, et al. Necrotic tumor versus brain abscess: importance of amino acids detected at 1-H MR spectroscopy—initial results. Radiology 1999;213:785–793
    CrossRefPubMedWeb of Science
  13. ↵
    Burtscher IM, Skagerberg G, Geijer B, Englund E, Ståhlberg F, Holtås S. Proton MR spectroscopy and preoperative diagnostic accuracy: an evaluation of intracranial mass lesions characterized by stereotactic biopsy findings. AJNR Am J Neuroradiol 2000;21:84–93
    Abstract/FREE Full Text
  14. ↵
    Shimizu H, Kumabe T, Shirane R, Yoshimoto T. Correlation between choline level measured by proton MR spectroscopy and Ki-67 labeling index in gliomas. AJNR Am J Neuroradiol 2000;21:659–665
    Abstract/FREE Full Text
  15. ↵
    Castillo M, Smith JK, Kwock L. Correlation of myo-inositol levels and grading of cerebral astrocytomas. AJNR Am J Neuroradiol 2000;21:1645–1649
    Abstract/FREE Full Text
  16. ↵
    Bendszus M, Warmuth-Metz M, Klein R, et al. MR spectroscopy in gliomatosis cerebri. AJNR Am J Neuroradiol 2000;21:375–380
    Abstract/FREE Full Text
  17. ↵
    Butzen J, Prost R, Chetty V, et al. Discrimination between neoplastic and nonneoplastic brain lesions by use of proton MR spectroscopy: the limits of accuracy with logical regression model. AJNR Am J Neuroradiol 2000;21:1213–1219
    Abstract/FREE Full Text
  18. ↵
    Kimura T, Sako K, Gotoh T, Tanaka K, Tanaka T. In vivo single-voxel proton MR spectroscopy in brain lesions with ring-like enhancement. NMR Biomed 2001;14:339–349
    CrossRefPubMedWeb of Science
  19. ↵
    Dowling C, Bollen AW, Noworolski SM, et al. Preoperative proton MR spectroscopic imaging of brain tumors: correlation with histopathologic analysis of resection specimens. AJNR Am J Neuroradiol 2001;22:604–612
    Abstract/FREE Full Text
  20. ↵
    Schlemmer HP, Bachert P, Herfarth KK, Zuna I, Debus J, van Kaick G. Proton MR spectroscopic evaluation of suspicious brain lesions after stereotactic radiotherapy. AJNR Am J Neuroradiol 2001;22:1316–1324
    Abstract/FREE Full Text
  21. Tzika AA, Cheng LL, Goumnerova L, et al. Biochemical characterization of pediatric brain tumors by using in vivo and ex vivo magnetic resonance spectroscopy. J Neurosurg 2002;96:1023–1031
    PubMed
  22. ↵
    Tzika AA, Zarifi MK, Goumnerova L, et al. Neuroimaging in pediatric brain tumors: Gd-DTPA-enhanced, hemodynamic, and diffusion MR imaging compared with MR spectroscopic imaging. AJNR Am J Neuroradiol 2002;23:322–333
    Abstract/FREE Full Text
  23. ↵
    Moller-Hartmann W, Herminghaus S, Krings T, et al. Clinical application of proton magnetic resonance spectroscopy in the diagnosis of intracranial mass lesions. Neuroradiology 2002;44:371–381
    CrossRefPubMedWeb of Science
  24. ↵
    Sener RN. Longstanding tectal tumors: proton MR spectroscopy and diffusion MRI findings. Comput Med Imaging Graph 2002;26:25–31
    PubMed
  25. ↵
    Krabbe K, Gideon P, Wang P, Hansen U, Thomsen C, Madsen F. MR diffusion imaging of human intracranial tumors. Neuroradiology 1977;39:483–489
  26. ↵
    Le Bihan D, Breton E, Lallemand D, Grenier P, Cabanis E, Laval-Jeantet M. MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders. Radiology 1986;161:401–407
    PubMedWeb of Science
  27. ↵
    Hajnal JV, Doran M, Hall AS, et al. MR imaging of anisotropically restricted diffusion of water in the nervous system: technical, anatomic, and pathologic considerations. J Comput Assist Tomogr 1991;15:1–18
    PubMedWeb of Science
  28. ↵
    Tien RD, Felsberg GJ, Friedman H, Brown M, MacFall J. MR imaging of high-grade cerebral gliomas: value of diffusion-weighted echoplanar pulse sequences. AJR Am J Roentgenol 1994;162:671–677
    PubMedWeb of Science
  29. ↵
    Brunberg JA, Chenevert TL, McKeever PE, et al. In vivo MR determination of water diffusion coefficients and diffusion anisotropy: correlation with structural alteration in gliomas of the cerebral hemispheres. AJNR Am J Neuroradiol 1995;16:361–371
    Abstract/FREE Full Text
  30. ↵
    Noguchi K, Watanabe N, Nagayoshi T, et al. Role of diffusion-weighted echo-planar MRI in distinguishing between brain abscess and tumour: a preliminary report. Neuroradiology 1999;41:171–174
    CrossRefPubMed
  31. ↵
    Stadnik TW, Chaskis C, Michotte A, et al. Diffusion-weighted MR imaging of intracerebral masses: comparison with conventional MR imaging and histologic findings. AJNR Am J Neuroradiol 2001;22:969–976
    Abstract/FREE Full Text
  32. ↵
    Kono K, Inoue Y, Nakayama K, et al. The role of diffusion-weighted imaging in patients with brain tumors. AJNR Am J Neuroradiol 2001;22:1081–1088
    Abstract/FREE Full Text
  33. ↵
    Filippi CG, Edgar MA, Uluǧ AM, Prowda JC, Heier LA, Zimmerman RD. Appearance of meningiomas on diffusion-weighted images: Correlating diffusion constants with histopathologic findings. AJNR Am J Neuroradiol 2001;22:65–72
    Abstract/FREE Full Text
  34. ↵
    Le Bihan D, Douek P, Argyropoulou M, Turner R, Patronas N, Fulham M. Diffusion and perfusion magnetic resonance imaging in brain tumors. Top Magn Reson Imaging 1993;5:25–31
    PubMed
  35. Eis M, Els T, Hoehn-Berlage M, Hossman KA. Quantitative diffusion MR imaging of cerebral tumor and edema. Acta Neurochir Suppl (Wien) 1994;60:344–346
    PubMed
  36. ↵
    Castillo M, Smith JK, Kwock L, Wilber K. Apparent diffusion coefficients in the evaluation of high-grade cerebral gliomas. AJNR Am J Neuroradiol 2001;22:60–64
    Abstract/FREE Full Text
  37. ↵
    Maier SE, Bogner P, Bajzik G, et al. Normal brain and brain tumor: multicomponent apparent diffusion coefficient line scan imaging. Radiology 2001;219:842–849
    CrossRefPubMedWeb of Science
  38. ↵
    Sinha S, Bastin ME, Whittle IR, Wardlaw JM. Diffusion tensor MR imaging of high-grade cerebral gliomas. AJNR Am J Neuroradiol 2002;23:520–527
    Abstract/FREE Full Text
  39. ↵
    Law M, Cha S, Knopp EA, Johnson G, Arnett J, Litt AW. High-grade gliomas and solitary metastases: differentiation by using perfusion and proton spectroscopic MR imaging. Radiology 2002;222:715–721
    PubMedWeb of Science
  40. ↵
    Sijens PE, Knopp MV, Brunetti A, et al. H-1 spectroscopy in patients with metastatic brain tumors: a multicenter study. Magn Reson Med 1995;33:818–826
    CrossRefPubMedWeb of Science
  41. Negendank WG, Sauter R, Brown TR, et al. Proton magnetic resonance spectroscopy in patients with glial tumors: a multicenter study. J Neurosurg 1996;84:449–458
    CrossRefPubMedWeb of Science
  42. Pruel MC. Accurate noninvasive diagnosis of human brain tumors by using proton magnetic resonance spectroscopy. Nature Med 1996;2:323–325
    CrossRefPubMedWeb of Science
  43. Tedeschi G, Lundbom N, Raman R, et al. Increased choline signal coinciding with malignant degeneration of cerebral gliomas: a serial proton magnetic resonance spectroscopy imaging study. J Neurosurg 1997;87:516–524
    PubMedWeb of Science
  44. ↵
    Rand SD, Prost R, Haughton V, et al. Accuracy of single-voxel proton MR spectroscopy in distinguishing neoplastic from non-neoplastic brain lesions. AJNR Am J Neuroradiol 1997;18:1695–1704
    Abstract
  45. ↵
    Remy C, Grand S, Lai ES, et al. 1H MRS of human brain abscesses in vivo and in vitro. Magn Reson Med 1995;34:508–514
    PubMed
  46. ↵
    Gupta RK, Vatsal DK, Husain N, et al. Differentiation of tuberculous from pyogenic brain abscesses with in vivo proton MR spectroscopy and magnetization transfer MR imaging. AJNR Am J Neuroradiol 2001;22:1503–1509
    Abstract/FREE Full Text
  47. ↵
    Jayasundar R, Singh VP, Raghunathan P, Jain K, Banerji AK. Inflammatory granulomas: evaluation with proton MRS. NMR Biomed 1999;12:139–144
    CrossRefPubMedWeb of Science
  48. ↵
    Lee DY, Chung CK, Hwang YS, et al. Dysembryoplastic neuroepithelial tumor: radiological findings (including PET, SPECT, and MRS) and surgical strategy. J Neurooncol 2000;47:167–174
    CrossRefPubMed
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 24 (2)
American Journal of Neuroradiology
Vol. 24, Issue 2
1 Feb 2003
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Combination of Single-Voxel Proton MR Spectroscopy and Apparent Diffusion Coefficient Calculation in the Evaluation of Common Brain Tumors
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
Nail Bulakbasi, Murat Kocaoglu, Fatih Örs, Cem Tayfun, Taner Üçöz
Combination of Single-Voxel Proton MR Spectroscopy and Apparent Diffusion Coefficient Calculation in the Evaluation of Common Brain Tumors
American Journal of Neuroradiology Feb 2003, 24 (2) 225-233;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Combination of Single-Voxel Proton MR Spectroscopy and Apparent Diffusion Coefficient Calculation in the Evaluation of Common Brain Tumors
Nail Bulakbasi, Murat Kocaoglu, Fatih Örs, Cem Tayfun, Taner Üçöz
American Journal of Neuroradiology Feb 2003, 24 (2) 225-233;
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Methods
    • Results
    • Discussion
    • Conclusion
    • Acknowledgments
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Extra-axial tentorial medulloblastoma: a rare presentation of a common posterior fossa tumour
  • Diffusion-Weighted Imaging and Diffusion Tensor Imaging for Differentiating High-Grade Glioma from Solitary Brain Metastasis: A Systematic Review and Meta-Analysis
  • MR Fingerprinting of Adult Brain Tumors: Initial Experience
  • MRI Grading versus Histology: Predicting Survival of World Health Organization Grade II-IV Astrocytomas
  • Methodology of diffusion-weighted, diffusion tensor and magnetisation transfer imaging
  • MR Spectroscopy in Radiation Injury
  • Usefulness of diffusion/perfusion-weighted MRI in patients with non-enhancing supratentorial brain gliomas: a valuable tool to predict tumour grading?
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Usefulness of Quantitative Susceptibility Mapping for the Diagnosis of Parkinson Disease
  • White Matter Alterations in the Brains of Patients with Active, Remitted, and Cured Cushing Syndrome: A DTI Study
  • Qualitative and Quantitative Analysis of MR Imaging Findings in Patients with Middle Cerebral Artery Stroke Implanted with Mesenchymal Stem Cells
Show more BRAIN

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

Special Collections

  • AJNR Awards
  • ASNR Foundation Special Collection
  • Most Impactful AJNR Articles
  • Photon-Counting CT
  • Spinal CSF Leak Articles (Jan 2020-June 2024)

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire