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Middle Interhemispheric Variant of Holoprosencephaly Associated with Diffuse Polymicrogyria

Jun-ichi Takanashi, A. James Barkovich, Nancy J. Clegg and Mauricio R. Delgado
American Journal of Neuroradiology March 2003, 24 (3) 394-397;
Jun-ichi Takanashi
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A. James Barkovich
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Nancy J. Clegg
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Mauricio R. Delgado
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    Fig 1.

    MR images obtained when the patient was aged 3 weeks.

    A and B, Fast spin-echo T2-weighted (TR/TE/NEX, 5460/106/2) (A) and spin-echo T1-weighted (540/14/1) (B) images show interhemispheric fusion of the gray matter and white matter (arrow in A) and an absence of the IHF in the posterior frontal and parietal lobes. The gyral pattern is abnormal, showing an increased cortical thickness and extensive irregularity of the cortical–white matter junction in the bilateral frontal and parietal lobes.

    C, Coronal fast spin-echo T2-weighted image shows interhemispheric fusion of the gray and white matter (arrow) and subcortical heterotopia (arrowhead).

    D, Sagittal spin-echo T1-weighted image shows a hypoplastic basis pontis.

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American Journal of Neuroradiology: 24 (3)
American Journal of Neuroradiology
Vol. 24, Issue 3
1 Mar 2003
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Cite this article
Jun-ichi Takanashi, A. James Barkovich, Nancy J. Clegg, Mauricio R. Delgado
Middle Interhemispheric Variant of Holoprosencephaly Associated with Diffuse Polymicrogyria
American Journal of Neuroradiology Mar 2003, 24 (3) 394-397;

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Middle Interhemispheric Variant of Holoprosencephaly Associated with Diffuse Polymicrogyria
Jun-ichi Takanashi, A. James Barkovich, Nancy J. Clegg, Mauricio R. Delgado
American Journal of Neuroradiology Mar 2003, 24 (3) 394-397;
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