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Abstract
SUMMARY: The 3D edge-enhancing gradient-echo (EDGE) MR imaging sequence offers superior contrast-to-noise ratio in the detection of focal cortical dysplasia. EDGE could benefit from 7T MR imaging but also faces challenges such as image inhomogeneity and low acquisition efficiency. We propose an EDGE-MP2RAGE sequence that can provide both EDGE and T1-weighted contrast, simultaneously, improving data-acquisition efficiency. We demonstrate that with sequence optimization, EDGE images with sufficient uniformity and T1-weighted images with high gray-to-white matter contrast can be achieved.
ABBREVIATIONS:
- CNR
- contrast-to-noise ratio
- EDGE
- edge-enhancing gradient-echo
- FCD
- focal cortical dysplasia
- INV
- inversion imaging
- © 2023 by American Journal of Neuroradiology
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