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Research ArticleAdult Brain

Edge-Enhancing Gradient-Echo MP2RAGE for Clinical Epilepsy Imaging at 7T

S. Tao, X. Zhou, E. Greco, V. Gupta, B.E. Freund, E.M. Westerhold, A.M. Feyissa, W.O. Tatum, S. Grewal, V. Patel and E.H. Middlebrooks
American Journal of Neuroradiology March 2023, 44 (3) 268-270; DOI: https://doi.org/10.3174/ajnr.A7782
S. Tao
aFrom the Departments of Radiology (S.T., X.Z., E.G., V.G., E.M.W., V.P., E.H.M.)
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X. Zhou
aFrom the Departments of Radiology (S.T., X.Z., E.G., V.G., E.M.W., V.P., E.H.M.)
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E. Greco
aFrom the Departments of Radiology (S.T., X.Z., E.G., V.G., E.M.W., V.P., E.H.M.)
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V. Gupta
aFrom the Departments of Radiology (S.T., X.Z., E.G., V.G., E.M.W., V.P., E.H.M.)
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B.E. Freund
bNeurology (B.E.F., A.M.F., W.O.T.)
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E.M. Westerhold
aFrom the Departments of Radiology (S.T., X.Z., E.G., V.G., E.M.W., V.P., E.H.M.)
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A.M. Feyissa
bNeurology (B.E.F., A.M.F., W.O.T.)
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W.O. Tatum
bNeurology (B.E.F., A.M.F., W.O.T.)
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S. Grewal
cNeurosurgery (S.G., E.H.M.), Mayo Clinic, Jacksonville, Florida
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V. Patel
aFrom the Departments of Radiology (S.T., X.Z., E.G., V.G., E.M.W., V.P., E.H.M.)
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E.H. Middlebrooks
aFrom the Departments of Radiology (S.T., X.Z., E.G., V.G., E.M.W., V.P., E.H.M.)
cNeurosurgery (S.G., E.H.M.), Mayo Clinic, Jacksonville, Florida
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    FIG 1.

    Examples of WM and GM longitudinal magnetizations (Mz) evolution in a repetition period (TR) for the EDGE (A) and EDGE-MP2RAGE (B) sequences. With EDGE contrast (A), the center of the data-acquisition window, which coincides with the k-space center (ie, k = 0), is placed when WM and GM have comparable signal intensity but opposite polarity. With EDGE-MP2RAGE (B), the first acquisition (ie, INV 1) is designed to provide the EDGE contrast. A.U. indicates arbitrary unit.

  • FIG 2.
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    FIG 2.

    Examples of EDGE (INV 1, A–C) images and T1-weighted (T1w) images (D–F) acquired with the EDGE-MP2RAGE reformatted into sagittal, axial, and coronal planes. The ROI (red circles in A–C) for WM and GM signal intensity measurements are also shown.

Tables

  • Figures
  • EDGE-MP2RAGE sequence parameters

    Acquisition PlaneTR (Sec)TI1/TI2 (Sec)FA1/FA2BW (Hz/px)AccelerationFOV (mm2)MatrixResolution (mm3)
    Sagittal4.50.8/2.75°/4°2003×230 × 230 × 154296 × 296 × 1920.8 × 0.8 × 0.8
    • Note:—FA indicates flip angle; BW, bandwidth.

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American Journal of Neuroradiology: 44 (3)
American Journal of Neuroradiology
Vol. 44, Issue 3
1 Mar 2023
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Cite this article
S. Tao, X. Zhou, E. Greco, V. Gupta, B.E. Freund, E.M. Westerhold, A.M. Feyissa, W.O. Tatum, S. Grewal, V. Patel, E.H. Middlebrooks
Edge-Enhancing Gradient-Echo MP2RAGE for Clinical Epilepsy Imaging at 7T
American Journal of Neuroradiology Mar 2023, 44 (3) 268-270; DOI: 10.3174/ajnr.A7782

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Edge-Enhancing MP2RAGE for Epilepsy at 7T
S. Tao, X. Zhou, E. Greco, V. Gupta, B.E. Freund, E.M. Westerhold, A.M. Feyissa, W.O. Tatum, S. Grewal, V. Patel, E.H. Middlebrooks
American Journal of Neuroradiology Mar 2023, 44 (3) 268-270; DOI: 10.3174/ajnr.A7782
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