Article Figures & Data
Figures
- Fig 1.
Imaging characteristics of IDH1-wild type and IDH1-mutant gliomas. A, A 24-year-old woman with an IDH1-wild type lower grade glioma (anaplastic astrocytoma, World Health Organization grade III). The imaging features are as follows: a lobar location, proportion of enhancing tumor of >33%, and poorly defined nonenhancing margin. B, A 42-year-old man with an IDH1-mutant lower grade glioma (anaplastic astrocytoma, WHO grade III). The imaging features are as follows: a lobar location with focal distribution, proportion of enhancing tumor of <33%, and well-defined nonenhancing margin.
- Fig 2.
Imaging characteristics of IDH1-mutant, no 1p/19q-codeletion and IDH1-mutant, 1p/19q-codeleted gliomas. A, A 34-year-old man with an IDH1-mutant, no 1p/19q-codeletion glioma (diffuse astrocytoma, World Health Organization grade II). The nonenhancing T2 hyperintense mass shows increased diffusivity. B, A 49-year-old woman with an IDH1-mutant, 1p/19q-codeleted glioma (oligodendroglioma, WHO grade II). The infiltrative T2 hyperintense mass shows a mixed pattern of high and intermediate ADC values.
Tables
- Table 1:
Prediction for an IDH1-mutation status in lower grade gliomas using the LASSO procedure
Imaging Parameters Adjusted Odds Ratio for IDH-Wild Type LGGs (WHO grade II/III gliomas) Nonlobar location 2.38 Proportion of enhancing tumor of >33% 1.66 Multifocal/multicentric distribution 2.93 Poor definition of nonenhancing margin 1.30 WHO grade II gliomas Side of tumor epicenter (central) 1.36 Multifocal/multicentric distribution 7.00 Pial invasion 1.48 Ependymal involvement 1.62 WHO grade III gliomas Nonlobar location 2.33 Proportion of enhancing tumor of >33% 1.25 Multifocal/multicentric distribution 2.27 Cortical involvement 0.99
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