Diagnostic Accuracy of Arterial Spin-Labeling MR Imaging in Detecting the Epileptogenic Zone: Systematic Review and Meta-analysis

Results of the QUADAS-2 tool. Risk of bias and applicability concerns summary (upper table). Risk of bias and applicability concerns graph (lower table).

Forest plot showing the sensitivity for each specific study on the right y-axis and the specificity of the accuracy of ASL for detecting the epileptogenic zone.

Summary receiver operating characteristic curves with prediction and confidence contour, 95% confidence contour, and 95% prediction contour for all included studies for analyzing the accuracy of ASL in detecting the epileptogenic zone (n = 6). SENS indicates sensitivity; SPEC, specificity; AUC, area under the curve; SROC, summary receiver operating characteristic.

Forest plot showing the negative and positive likelihood ratios of the accuracy of ASL for each specific study on the right y-axis and in detecting the epileptogenic zone.

Subgroup analysis of the effect of age, measurement methods, and seizure phase on the detection of the epileptogenic zone using ASL.